• Frontline Plus for Dogs 23-44 lbs - BLUE, 12 MONTH

    Frontline Plus for Dogs 23-44 lbs - BLUE, 12 MONTH

    Regular Price: $206.99Sale Price: $158.99
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    Temporary Price Reduction! FRONTLINE Plus Blue for Dogs 23-44 lbs

    Recommended by veterinarians, FRONTLINE Plus Blue for Dogs 23-44 pounds is a powerful and easy-to-use formula designed to quickly and effectively kill fleas, ticks, and chewing lice. FRONTLINE Plus is specially formulated for dogs weighing 23 - 44 pounds. Available without a prescription, FRONTLINE Plus only needs to be applied once a month for thorough pest control.

    life cycle of the commom flea
    Flea life cycle.
    View larger.
    life cycle of ticks
    Tick life cycle.
    View larger.

    Quickly Kills Fleas, Ticks, and Chewing Lice

    This powerful formula kills up to 100 percent of existing fleas in the first 12 hours after application, and it continues to kill new fleas for at least one month afterward. FRONTLINE Plus prevents the development of new fleas by destroying flea eggs and larvae and by destroying adult fleas before they have a chance to lay eggs. FRONTLINE kills chewing lice and all four major ticks, including ticks that may carry Lyme disease, keeping both your pet and your family protected.

    Waterproof Formula

    Thanks to its waterproof formula, FRONTLINE Plus won't rinse off when you give your dog a bath or when your dog goes for a swim. The active ingredient in FRONTLINE, fipronil, is stored in the natural oils in your dog's coat, so your pet is sure to stay protected no matter how many puddles he or she tramps through.

    EPA Registered Logo

    This FRONTLINE Plus product is EPA approved and registered, so it's guaranteed to be the exact same product sold by your Veterinarian. Click here for more information on EPA-approved pet products.

    Package Contents

    Box includes three 1.34-milliliter tubes of FRONTLINE Plus for Dogs.

    FRONTLINE Plus Blue
    for Dogs 23 - 44 lbs
    • Kills fleas, flea eggs, ticks, and
      chewing lice
    • Fast-acting formula
    • Includes 12 one-month
    • Waterproof formula
    • Easy-to-use applicator
    • For dogs weighing 23-44
    • Per Dose: $11.58
    More Info
    Got Fleas?

    A product guide to flea
    and tick products.

    Flea Facts You Should Know

    Interesting flea facts to help your
    pets be pest free.

    Fleas: Understanding the Enemy

    All about fleas and prevention.


    Helpful information on ticks and your

    FAQs about Fleas and Ticks
    Frontline Plus for Dogs Lifestyle shot
    FRONTLINE Plus for Dogs is Available In:
    (0 - 22 pounds)
    (23 - 44 pounds)
    (45 - 88 pounds)
    (89 - 132 pounds)
    3 month
    6 month
    12 month
    3 month
    6 month
    12 month
    3 month
    6 month
    12 month
    3 month
    6 month
    12 month

    Usage Info

    How FRONTLINE Plus Works

    Use FRONTLINE Plus for fast-acting, long-lasting flea and tick control. When you apply FRONTLINE, fipronil, the active ingredient, is stored in the oil glands under your pet's skin. It's then distributed continuously to the skin and hair of your pet through the hair follicles. This way, FRONTLINE provides waterproof, month-long protection against future pests while breaking down the flea and tick life cycles.

    Simple Three-Step Application

    Applying FRONTLINE Plus to your pet is an easy three-step process. First, remove the Frontline Plus applicator from the child-resistant package and cut or lift off the plastic tab to expose the foil and then peel the foil down. Next, hold the applicator upright and away from your face and body and snap off the tip. Finally, place the Frontline Plus applicator tip on the skin between your pet's shoulder blades and squeeze the applicator to apply the entire contents in a single spot onto your pet's skin.

    To prevent harm to you and your pet, read the entire label and enclosed directions before each use. Follow all directions and precautionary statements carefully.


    To prevent harm to you and your pet, read the entire label and enclosed directions before each use. Follow all directions and precautionary statements carefully. Always point the applicator away from your face, especially your eyes, and wash your hands thoroughly after application. USE ON DOGS ONLY. Do not use on rabbits or other animals.

    Weight Dosage
    Up to 22 pounds Apply contents of one applicator (0.67 milliliter) once per month
    23 - 44 pounds Apply contents of one applicator (1.34 milliliters) once per month
    45 - 88 pounds Apply contents of one applicator (2.68 milliliters) once per month
    89 - 132 pounds Apply contents of one applicator (4.02 milliliters) once per month
    All weights Apply contents of one applicator (0.5 milliliter) once per month




    Fipronil is a manufactured insecticide that works on a cellular level on adult fleas and ticks. It seeps into an insect's cells and blocks chlorine molecules from passing through. This stops the nervous system from working and paralyzes the insect.

    Fipronil kills adult fleas and ticks on contact or when consumed, and it can be spread from one insect to another.


    Because fipronil is so strong, it only needs to be applied once a month to continuously kill fleas and ticks. Once it is applied with an oily liquid to keep it on the skin of your dog, it slowly seeps into the hair follicles and oil glands where the fleas and ticks live.

    Main Purpose

    To kill adult fleas and ticks.


    Methoprene is an insect growth regulator, which means it works by affecting the eggs and larvae of fleas. It interrupts normal levels of growth hormone, preventing a juvenile flea from growing and molting, leading to death.


    Specifically designed to target developing larvae and eggs, methoprene prevents a flea population from increasing.

    Main Purpose

    To break the flea life cycle and stop further infestation.

    Active Ingredients % by Weight
    Fipronil 9.8%
    (S)-Methoprene 8.8%
    Inert Ingredients 81.4%
    Total 100%

    Some animals are sensitive or allergic to the ingredients in FRONTLINE, so be sure to watch for any signs of allergic reaction. If your pet shows signs of itching, restlessness, nausea, lethargy, or breathing difficulty, seek veterinary attention immediately.

    Net Contents

    Twelve tubes, each 0.046 fluid ounces (1.34 milliliters)

    Frontline Plus for Dogs 23-44 lbs - BLUE, 3 MONTHFrontline Plus for Dogs 23-44 lbs - BLUE, 3 MONTHReg price: $53.99
    Sale price: $40.99
    Frontline Plus for Dogs 23-44 lbs - BLUE, 6 MONTHFrontline Plus BlueReg price: $102.99
    Sale price: $78.99
    Frontline Plus for Dogs 45-88 lbs - PURPLE, 3 MONTHFrontline Plus for Dogs 45-88 lbs - PURPLE, 3 MONTHReg price: $54.99
    Sale price: $41.99
    Frontline Plus for Dogs 45-88 lbs - PURPLE, 6 MONTH6 Mo Frontline Plus LgReg price: $106.99
    Sale price: $81.99
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    Customer Reviews

    DISCLAIMER: The results described on the testimonials on this site, are the individual experiences and personal opinions of those who have purchased and used the products. These testimonials are not intended to make any claims that the products can be used to diagnose, treat, mitigate, cure or prevent any disease or medical condition.
    Click here to see all reviews
    Kills ticks by 4bostons from Chesapeake, VA01/24/2013

    This works very good for fleas, but we use it because of ticks. It provides good protection from ticks for 3-4 weeks.

    Great purchase by Shelby01/08/2013

    The vet recommended this product. It has worked great for my two dogs!

    Worth the money! by Zena11/29/2011

    You need to keep your pets on Frontline! The alternative will cost you much more in vet bills for lyme and/or ridding your house of fleas not to mention the comfort your pet receives from not having ticks and fleas. Don't even think twice about it! You have to use preventative!

    Entirley Satisfied by Floyd12/29/2012

    We started using Frontline on our Bichon "Buddy" with great results when he was just a puppy. His vet talked me into trying an oral tablet but it made him sick and we went back to Frontline. He tolerates it well and has had no fleas or ticks in the almost five years we have had him. The most economical way to buy it is purchasing a years supply from Entirley Pets online.

    Frontline plus vs pet armour by Tux from Chesapeake, va05/30/2012

    Frontline wins. We use frontline for protection against ticks. We have shorthaired dogs and found frontline stays on longer. Don't know why, maybe doesn't wash off as easily?

    flea meds. by gary from shenandoah,virgnia03/10/2014

    the same thing is was getting at the vets for a cheaper price .

    Don't let your best friend go without it by hallesmom from Greenville, SC11/13/2013

    I use Frontline for all my dogs...I have NEVER found a flea or tick on either of them..Best product on the market!

    great price - great product by happy customer from Bridgeport, WV05/03/2012

    You don't have to worry about fleas if you use this product monthly.

    This Product Works! by Dusty's mom from Pensacola, FL04/17/2012

    I couldn't be happier with this product. Easy to use and it works wonderfully!

    Really works by Nat from Renton, WA12/01/2011

    We use this for both of our pugs and we have zero flea problems.

    Good price performer by Owned by a Sheltie08/20/2014

    We've used Frontline Plus for many years and been happy with the results. Entirely Pets has the best price I've found.

    Frontline Plus Blue by Pat from Brooksville, Fl03/05/2012

    We live in Florida. So the problem with ticks and fleas is year round. We have had 3 dogs, now 2 and have never had a problem with either. After searching the internet we continue to purchase from Entirely Pets for the best prices.

    Great Product Best Price by meandmypets04/06/2012

    My dogs have been treated with Frontline Plus since they were puppies. They have remained flea and tick free. One of my dogs has severe allergies. Frontline Plus has never caused him an allergic reaction. While the product is rather expensive, the 12 month pack from EntirelyPets was the most reasonable price I could find. Great product, best price, free shipping - good stuff.

    flea by laurie06/11/2008

    i love this product i use on all my pets i have 2 dogs and 1 cat it works wonderful and easy to use

    using frontline plus for my cats and dog by ju from houston, tx11/06/2012

    use this product over 10 years for all of my pets. Do not have any problem.

    Dependable by 2Aussies from Youngsville NC10/25/2012

    I have used Frontline for years and my pets have been free of problems. I started using Entirely Pets about 5 years ago and their service and prices are great. I always check them first when I need something for my Aussies.

    Completely Satisfied by dihof3 from Georgia12/30/2012

    I have purchased Frontline Plus Blue several times from Entirely Pets. I always receive the product in a timely manner and feel that the price is the lowest that I can find.

    FrontlinePlus by furbabies mom from Hendersonville,NC03/28/2012

    I give this website 5 stars+..I ordered & recieved my order of Frontline Plus for my two Aussie's & am delighted to say the order was filled & sent to me in just 5 days. The price for this product is great & about half of what my Vet has been charging me, I am happy to get the low price for the Fronline Plus. I have used this website, Entirely Pets.com for many years, now with these two Aussies & for 6 yrs for my Husky who passed on 4 yrs ago. I did get all of her meds here & saved quite a bit of money from using EntirelyPets.com. Thanks for keeping your prices low & your service is great. Furbabies Mom

    by from 10/30/2011

    by dls07/18/2014

    the product is fine, I have used this since we have our dog.

    flea and tick control by caroline hannold02/28/2014

    I've been using frontline plus as per my special vet Dr. Judy Morgan Clayton Veterinary Asso. We have five adopted animals and have used this product for 30 or more years with great success. We would not use anything else for our dear furry friends. Its the best!

    The Best by jeani01/07/2014

    I have had dogs for about 40 years. Not sure how long I have used frontline but I have no desire to change to another being frontline does its job. Living in the country we have tons of ticks with all the wildlife passing through the surrounding area. Great product

    Frontline Plus Blue for Dogs by pin11/15/2012

    great and I like being able to get in 6 months supply

    Frontline Plus Blue.23 to 44 pounds by Debster from Lakeland, Fla05/30/2012

    I have always used Frontline Plus, on rare occasions, I have used Comfortis during a particularly bad flea time, but Frontline Plus is my go to flea medicine of choice.

    Great Service! by Jersey Jo01/01/2013

    Found Entirely Pets to have the best price for Frontline Plus products and received fast and free delivery!

    Best Price Online by DogMom5504/11/2013

    It was as described, and a great price. With the free-shipping, I was saved a lot of money by buying Frontline on Entirely Pets.

    Have the fleas become resistant? by CG10/29/2011

    We've been buying Frontline Plus for years, and never saw fleas on our dogs until last month. Our three terriers were suddenly covered with fleas and we switched to Comfortis, a prescription oral flea killer, and the fleas died within a day. The veterinary staff told us they had heard similar stories from other clients, so I'm wondering if there is a resistant strain of fleas emerging.

    Frontline Plus BLUE for Dogs 23-44 lbs, 12 MONTH by dihof3 from Georgia05/30/2012

    I was very pleased with my order. I have already recommended Entirely Pets to my friends and told them about the quality product at a good price.

    Excellent flea protection by 18thstlocal02/17/2014

    We've been using frontline for years with our dog and never had a problem with fleas.

    Ready for good weather by Jack&Jesse from Syracuse, ny04/16/2013

    good timing for a sale. now all set for spring & summer with flea and tick protection.

    Frontline by CP08/07/2012

    I've used it for years and never had flea problems.

    very disappointed by dogfriend04/25/2012

    I have several dogs and each one without exception continues to have fleas after application. This product does not last 30 days as a matter of fact it is not even effective for one day. It is way over priced for what it claims to do. I called the help line and they were of no help either.

    Works like it should by pupmom from westerville, oh03/17/2012

    I have been using Frontline for years and it does a great job keeping fleas and ticks off my pups.

    Excellent Protection by Lindsey from Bel Air, MD01/07/2014

    I have been using this product for years. It works great. Kills fleas and ticks!


    Questions and Answers

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