• 3 PACK Denosyl for dogs over 25 lbs (90 tablets) 225 mg

    3 PACK Denosyl for dogs over 25 lbs (90 tablets) 225 mg

    SKU: DENO225PK3
    Regular Price: $98.99Sale Price: $75.89
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    #1 Veterinarian Recommended LiverDenosyl is a nutritional supplement that helps minimize a variety of liver problems in dogs and cats. It has also been shown to improve liver health and function by protecting and repairing liver cells. It is recommended to improve hepatic glutathione levels in dogs and cats. For optimal absorption, give your dog or cat Denosyl on an empty stomach, at least an hour before feeding.

    Body weight Total daily administration and tablet size
    Up to 12 pounds (5.5 kg) One tablet of 90 mg
    13 to 34 pounds (6-15.5 kg) One tablet of 225mg
    35 to 65 pounds (16 to 29.5 kg) One tablet of 425 mg
    66 to 120 pounds (30 to 54.5 kg) Two tablets of 425 mg
    Over 120 pounds (54.5 kg +) Three tablets of 425 mg
    The number of tablets can be gradually reduced or may be increased at any time depending on the pet's needs.
    3-Pack Denosyl is a limited time offer

    Usage Information

    Ingredients: S-Adenosylmethionine

    Denosyl, a nutritional supplement, is the pure and stabilized salt of S-Adenosylmethionine for veterinary use only. It is the only brand researched in medical trials for veterinary use in dogs and cats.

    S-Adenosylmethionine is an endogenous molecule synthesized by cells throughout the body and is formed from the amino acid methionine and ATP. It is an essential part of three major chemical pathways in the body.

    Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidants that protects hepatic (liver) cells from toxins. A study found that low liver glutathione concentrations are common in dog and cats with decreased liver function.

    For optimal absorption, tablets should be given on an empty stomach, at least 1 hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulties administering tablets to their pets, this medication maybe disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach in cats, but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the table into the stomach. Denosyl 9- mg tablets are ideal for cats because of their small size.

    Storage: Store in a cool, dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.

    What does the liver do? The liver participates in many activities within the body. It helps the digestion of food through production of bile and helps change digested foods into substances used by the body for energy and growth. The liver also helps process some medications into material(s) that can be used by the body; the liver may assist in eliminating medications from the body once they have had their effect. The liver stores vitamins and minerals and works with sugar (carbohydrates, glucose), fats and proteins. It also helps maintain proper blood clotting and removes many body toxins from the blood. Without proper liver function, the pet's health is compromised.

    Because it does so much, the liver may be subject to many things: injury, both direct and indirect, infection, and toxicity. Some of the signs and symptoms of compromised liver function in pets may include: weakness, vomiting, poor appetite, and/or seizures. But if there is mild or early stage liver compromise, the pet can appear normal. If you notice any of these symptoms or your pet is just acting differently, you should contact your veterinarian. Many veterinarians run screening tests for middle aged and older patients during the annual examination to ensure that organ function is normal.

    Customer Reviews

    DISCLAIMER: The results described on the testimonials on this site, are the individual experiences and personal opinions of those who have purchased and used the products. These testimonials are not intended to make any claims that the products can be used to diagnose, treat, mitigate, cure or prevent any disease or medical condition.
    Click here to see all reviews
    Denosyl by Hope09/17/2013

    Great product at an even better price! Thanks

    great deal by nae11/12/2012

    This product has worked great for our dog has proably saved her life.

    Seems to be helping by LikesArt from Atlanta07/01/2013

    My rat terrier has been on this for several years (vet recommended) for liver support and it seems to be keeping her stable.

    Worked wonder by June from Upstate New York08/27/2013

    Denosyl, prescribed by my vet, is an excellent product. I buy fromEntirely Pets because of the low price offered and am very happy with their company.

    Good Product by DannieRae from Southeast, MO11/06/2012

    Denosyl is a supplement that my little dog is required to take daily for liver disfunction. The product is excellent along with the price. My problem is with the packaging. The boxes are often broken and bent when I receive them. Instead of packing these items in a mailing enevelope it would be much better to put them in a box. I have complained aabout this before. Also, be sure you check the date on the boxes as I have received them when they are out of date.

    Denosyl for dogs by malbee1023 from Batavia, NY05/13/2013

    I saved literally $20 per box by ordering here rather than getting it through the vet. It arrived 2 days after I placed my order, pretty fast. The blood work on my dog since taking it has improved.

    Denosyl by Sandi R.02/19/2013

    My sheltie went from complete liver failure to normal liver function in less than two weeks. She was on hepatic health dog food and took a denosyl every night. The vet said it was a miracle and couldn't believe her health change. She is back to normal food but still takes the denosyl. It's a small price to see her happy face when I get home!

    Does what's needed by jamie from New Jersey04/30/2013

    I've used this product for several years since my dog was diagnosed with "some liver problems". Apparently, it's working because Jamie no longer is at risk for liver disease. It's a supplement and doesn't seem to have any adverse affect. Worth a try!

    Best Purchase Ever by Fran from Brookfield, MA08/21/2012

    This product is great. I find the ordering process the best and most efficient, reliable and dependable. That is what I needed and that is what I received. Customer Service is outstanding.

    denosyl by sandy from Westchester NY10/23/2012

    Product is fantastic. Has maintained my dog's liver in a reasonalbly healthy state. She is on Phenobarbital which can distroy the liver. Have used denosyl for 5 years. My dog is now 15 yrs. old and going strong.

    My vet recommended Denosyl by pj from Baltimore10/16/2013

    My dog has Cushings disease and this is supposed to help aid her liver function. I can't really tell how well it works. She's been on it for 5 years. I only buy it at Entirely Pets, though I search the web for deal every few months. Entirely Pets always has the best price to be found for Denosyl.

    Great product, price! by Carol P10/12/2011

    My vet prescribed Denosyl for my dog, who has mild liver failure due to diabetes. This med has greatly improved his liver function. Entirly Pets has the best price for his product and delivers it promptly to your home.

    by Ro03/07/2013

    This product is wonderful...I have used it for my pet Polo for nine years....sadly I just lost him at 14 to his liver issues...but this procuct did help over the years to rebuild his liver function

    Best Purchase Ever by Puggie01/31/2012

    Since we have been giving this product to our dog, there has been a significant improvement with his health. (We know this through his recent test results.)

    Excellent product! by JoeB from Vancouver, WA02/05/2013

    This is a great product. Adds years to the life of your dog.

    For Health's Sake by Roses1 from California05/30/2012

    My senior aged dog has had elevated liver enzymes for the past few years. With Denosyl the health of her liver has stabilized. Great product.

    Good price for a 3 pack by Soosie06/09/2012

    Good service and prices. My dog takes Denosyl all the time so it was important to find a reasonable source for me to purchase on a regular basis. Thanks for being there.

    Great Value by Baldwin's Mom04/01/2012

    My Boston Terrier must take Denosyl, probably for the rest of his life. Entirely Pets saves me a bundle. I love my vet, but medication prices are ridiculous. I like having this product shipped right to our home, at a fair price. Thanks.

    EntirelyPets is a good value by Soosie from St. Louis, Mo.01/28/2012

    The best price for our dog's pills. A good website to order from and there are lots of other good values in pet care products.

    by from 05/28/2008

    My dog has been taking denosyl for over 1yr after he had a bout with pancreatitis...he's doing so well now you'd never know he even suffered from it.

    a by special from dietIn


    Great Purchase by Rose from Virginia11/05/2012

    I purchased this product at a great price & deliverly was awesome. Will definitely purchase again.

    Best price for these meds by IfNotForSitsWhyWarm from Lexington, KY04/01/2013

    This was prescribed by our vet for our older cocker spaniel. She takes it every day, so I have had to find the best price to make the cost hit lower. I assume it works as expected since our vet continues to prescribe it.

    Denosyl by ds02/10/2012

    A great product. My 17 year old Welsh Terrier dog's blood work proves it.

    Liver Supplement by If vet recommended from Shelton Washington02/18/2014

    Our vet suggested we buy this product online to save money. I have been buying it from Entirely Pets for several years and am very satisfied with the company.

    Saved my dogs life by TaraTriniti from Lafayette La06/21/2013

    I could not have asked for a better product!!!!!!

    Excellent product by sunsetreef from Redington shores Florida10/28/2011

    Our dog has been taking this product for some time now and he is improving every day.

    Great price... by mrsclean02/09/2013

    I have not found a better price or better service. Very happy I found EntirelyPets.

    by Murph04/05/2013

    The cost is lowest I have seen and I received the medication in a very timely manner.

    by kit12/05/2011

    these seem to effectively improve my beagle's liver function. have been using them for a couple of years now.

    Seems to help. by Nan03/24/2013

    My Miniature Schnauzer was suffering from multiple seizures a day. Since starting her on Denosyl she has not experienced any seizures.It might be coincidence, but If its not the Densoyl "helping", it's not hurting either.

    denosyl for dogs by frang from Virginia Beach,VA.06/05/2012

    great price, fast shipping.....best of both worlds.

    Excellent value by Savanna from Waterford, Mi.07/28/2012

    I love the option of buying a three pack. I have two dogs who take the same dose so one pack only lasts me fifteen days. With the three pack it's convenient and economical. I wish the product would be offered in chewables three pack as the dogs don't like the taste so I put them in Pill Pockets.

    by Huck11/16/2011


    Better Buy by TerryL from North East Alabama07/01/2013

    I was so relieved to find Denosyl at a better price. My Welsh Cardigan Corgi has liver disease and needs this product daily. I ordered the exact same product that I was getting at my vet's but at nearly a 50% savings. Since I recently lost my job, finding Denosyl at EntirelyPets.com was a big relief.

    Denasyl for Medium Dogs by Rayjay12/07/2011

    Good product, excellent service and good price. Very satisfied with purchase on line.

    liver support by kit1308 from Tucson, AZ03/17/2012

    Our elderly dog is on phenobarbitol for seizures. These provide liver support for him and keep his numbers close to the normal zone.

    by Mel from Singapore06/19/2012

    Product is ok. But we were supposed to purchase the CHEWABLE form.

    Great product by DrD1953 from Carbondale, IL05/28/2011

    I have two 14 year old Shih-Tzus (litter mates)who have liver problems. One, Cocoa, would vomit after eating. Since her liver enzymes were off, the vet recommended Denosyl. She started eating and not vomitting, her energy levels returned to normal energy. I stopped after about 3 months and she again began to vomit after eating I went back to giving her Denosyl and she again stopped vomitting after eating. A few months later, her sister, Molly, began refusing to eat at regular times, she would refuse some meals and then eat after she had missed a couple of meals. She was eating about 1/3 or her normal diet and was losing weight. She looked very ill. I had her checked at the vet, but they couldn't find anything wrong except some liver enzymes being too high. I tried Denosyl and she has returned to her normal appetite and diet. I don't usually write reviews, but this product has been a life safer to my aging Shih-Tzus!

    Denosyl by Gumbeaux03/15/2013

    Always buy from Entirely Pets---best prices and prompt delivery!

    Helps protect liver by KitS from Tucson, AZ06/12/2012

    Our beagle has epilepsy and takes phenobarbital. The denosyl was recommended by our vet to protect his liver several years ago. He is now 17 and doing quite well.


    Questions and Answers

    6 Pack Denosyl for small dogs and cats (180 tablets) 90 mg6 Pack Denosyl for small dogs and cats (180 tablets) 90 mg
    Reg price: $141.99
    Sale price: $108.99
    Denosyl for dogs over 25 lbs (30 tablets) 225 mgDenosyl for dogs over 25 lbs (30 tablets) 225 mg
    Reg price: $36.99
    Sale price: $27.99
    6 Pack Denosyl for dogs over 25 lbs (180 tablets) 225 mg6 Pack Denosyl for dogs over 25 lbs (180 tablets) 225 mg
    Reg price: $197.99
    Sale price: $151.79
    Denosyl for dogs over 35 lbs (30 tablets) 425 mgDenosyl for dogs over 35 lbs (30 tablets) 425 mg
    Reg price: $63.99
    Sale price: $48.99

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