Denosyl is a nutritional supplement that helps minimize a variety of liver problems in dogs and cats. It has also been shown to improve liver health and function by protecting and repairing liver cells. It is recommended to improve hepatic glutathione levels in dogs and cats. For optimal absorption, give your dog or cat Denosyl on an empty stomach, at least an hour before feeding.
FELINE AND CANINE DENOSYL SD4 ADMINISTRATION GUIDE
Total daily administration
and tablet size
Up to 12 pounds (5.5 kg)
One tablet of 90 mg
13 to 34 pounds (6-15.5 kg)
One tablet of 225mg
35 to 65 pounds (16 to 29.5 kg)
One tablet of 425 mg
66 to 120 pounds (30 to 54.5 kg)
Two tablets of 425 mg
Over 120 pounds (54.5 kg +)
Three tablets of 425 mg
The number of tablets can be gradually reduced or may be increased at any time depending on the pet's needs.
Denosyl, a nutritional supplement, is the pure and stabilized salt of S-Adenosylmethionine for veterinary use only. It is the only brand researched in medical trials for veterinary use in dogs and cats.
S-Adenosylmethionine is an endogenous molecule synthesized by cells throughout the body and is formed from the amino acid methionine and ATP. It is an essential part of three major chemical pathways in the body.
Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidants that protects hepatic (liver) cells from toxins. A study found that low liver glutathione concentrations are common in dog and cats with decreased liver function.
For optimal absorption, tablets should be given on an empty stomach, at least 1 hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulties administering tablets to their pets, this medication maybe disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach in cats, but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the table into the stomach. Denosyl 9- mg tablets are ideal for cats because of their small size.
Storage: Store in a cool, dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.
What does the liver do?
The liver participates in many activities within the body. It helps the digestion of food through production of bile and helps change digested foods into substances used by the body for energy and growth. The liver also helps process some medications into material(s) that can be used by the body; the liver may assist in eliminating medications from the body once they have had their effect. The liver stores vitamins and minerals and works with sugar (carbohydrates, glucose), fats and proteins. It also helps maintain proper blood clotting and removes many body toxins from the blood. Without proper liver function, the pet's health is compromised.
Because it does so much, the liver may be subject to many things: injury, both direct and indirect, infection, and toxicity. Some of the signs and symptoms of compromised liver function in pets may include: weakness, vomiting, poor appetite, and/or seizures. But if there is mild or early stage liver compromise, the pet can appear normal. If you notice any of these symptoms or your pet is just acting differently, you should contact your veterinarian. Many veterinarians run screening tests for middle aged and older patients during the annual examination to ensure that organ function is normal.
This product has regulated my cat's liver function. He is almost 19 and has taken this product for 6 yrs and is doing well.
improved liver function by Julie02/29/2008
My cat William had a poor prognosis when he was diagnosed with liver problems, cause unknown. He was immediately put on Denosyl and Marin, and after 6 months his liver values are almost normal!
Improved liver values by Dee01/07/2009
My dog Teddy has been on Denosyl for the last six years after being diagnosed by our Vet with poor liver values. His values improved to normal only after three months using the Denosyl. I started buying Denosyl from Entirelypets since it was almost half of what I paid the Vet for it. I kept him on one pill a day for maintenace and just recently increased him to two pills a day after a recent test showed his liver values were slightly elivated. After increasing to two pills a day his values are normal again. Teddy is now 16 going on 17 this year and I think the Denosyl has helped him live a longer, healthier life.
Necessary for dogs with lliver disease by Charlie10/18/2011
This product was recommended by my dogs veterinarian. She has liver disease and this is a great product to help reduce the changes of further liver damage.
Makes a Difference by Leesee10/30/2011
My geriatric kitty has been on Denosyl for the past four years and it has continued to make a positive difference in her liver enzyme values. The pills are easy for her to swallow and never seem to cause any sort of stomach upset as long as she takes them with a little bit of wet food. I highly recommend this product.
My dog is on this product for elevated liver enzymes and the enzymes are still elevated but have not increased. He is doing well.
DENOSYL by DEBBIE10/31/2011
This medicine was prescribed by my veternarian for my cat. Its works great. The vet was charging me $30.00 for a one month (30 Tabs) Supply. By ordering Denosyl from Entirely Pets I can get a 90 day supply (90 Tabs)for $51.99. which equals $17.33 per month instead of $30.00 the vet was charging. It is the exact same medicine that I was getting from the vet. I highly reccomend order from Entirely Pets. Items are delivered very quickly and are exactly what you ordered. I have been ordering for a while from them and I am highly satisfied.
Great company to do buniness with by Vicki04/19/2012
As always, great price for a great product! Will order again.
super quick service by gale12/15/2011
I recently ran out of denosyl for my little min pin, China. I waited to long to reorder. The product really does a great job for her, since she has liver problems. I ordered on a Thursday and did not really expect to see the package till Monday. To my surprise and gratitude, it showed up Saturday. I have ordered from another company, previously, and did not receive the product no where near as quickly. The price was not as good either. I will be getting her pills from Entirely Pets from now on. Thank you so much for your quick service.
Beats waiting at the vets office! by Misha10/19/2011
Order received quickly and much less money than the vets (and I didn't have to wait around for them to find it). I'll get my pet's supplements here in the future.
Best price by Francyn from St-Cesaire03/02/2012
Even my veterenean have your adresse now
by from 10/11/2011
Our 10 year old cat has had a liver problem for over 5 years. I usually buy 3 to 6 months worth of Denosyl for her. The costs are HALF what the vet wanted to charge for the exact same thing. Sales are always used when buy the products. Shipping in within a reasonable time frame too.