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3 Pack Denosyl for small dogs and cats (90 tablets) 90 mg

Item Number: DENO3PK90
Regular Price: $71.99Sale Price: $54.99
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#1 Veterinarian Recommended Liver Denosyl is a nutritional supplement that helps minimize a variety of liver problems in dogs and cats. It has also been shown to improve liver health and function by protecting and repairing liver cells. It is recommended to improve hepatic glutathione levels in dogs and cats. For optimal absorption, give your dog or cat Denosyl on an empty stomach, at least an hour before feeding.

Body weight Total daily administration and tablet size
Up to 12 pounds (5.5 kg) One tablet of 90 mg
13 to 34 pounds (6-15.5 kg) One tablet of 225mg
35 to 65 pounds (16 to 29.5 kg) One tablet of 425 mg
66 to 120 pounds (30 to 54.5 kg) Two tablets of 425 mg
Over 120 pounds (54.5 kg +) Three tablets of 425 mg
The number of tablets can be gradually reduced or may be increased at any time depending on the pet's needs.

Usage Information

Ingredients: S-Adenosylmethionine

Denosyl, a nutritional supplement, is the pure and stabilized salt of S-Adenosylmethionine for veterinary use only. It is the only brand researched in medical trials for veterinary use in dogs and cats.

S-Adenosylmethionine is an endogenous molecule synthesized by cells throughout the body and is formed from the amino acid methionine and ATP. It is an essential part of three major chemical pathways in the body.

Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidants that protects hepatic (liver) cells from toxins. A study found that low liver glutathione concentrations are common in dog and cats with decreased liver function.

For optimal absorption, tablets should be given on an empty stomach, at least 1 hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulties administering tablets to their pets, this medication maybe disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach in cats, but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the table into the stomach. Denosyl 9- mg tablets are ideal for cats because of their small size.

Storage: Store in a cool, dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.

What does the liver do? The liver participates in many activities within the body. It helps the digestion of food through production of bile and helps change digested foods into substances used by the body for energy and growth. The liver also helps process some medications into material(s) that can be used by the body; the liver may assist in eliminating medications from the body once they have had their effect. The liver stores vitamins and minerals and works with sugar (carbohydrates, glucose), fats and proteins. It also helps maintain proper blood clotting and removes many body toxins from the blood. Without proper liver function, the pet's health is compromised.

Because it does so much, the liver may be subject to many things: injury, both direct and indirect, infection, and toxicity. Some of the signs and symptoms of compromised liver function in pets may include: weakness, vomiting, poor appetite, and/or seizures. But if there is mild or early stage liver compromise, the pet can appear normal. If you notice any of these symptoms or your pet is just acting differently, you should contact your veterinarian. Many veterinarians run screening tests for middle aged and older patients during the annual examination to ensure that organ function is normal.

Customer Reviews

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4.88 rating based on 78 reviews
super quick service by gale12/15/2011

I recently ran out of denosyl for my little min pin, China. I waited to long to reorder. The product really does a great job for her, since she has liver problems. I ordered on a Thursday and did not really expect to see the package till Monday. To my surprise and gratitude, it showed up Saturday. I have ordered from another company, previously, and did not receive the product no where near as quickly. The price was not as good either. I will be getting her pills from Entirely Pets from now on. Thank you so much for your quick service.

by Louise12/10/2011

My dog is on this product for elevated liver enzymes and the enzymes are still elevated but have not increased. He is doing well.

denosyl by Judy03/07/2012

This product has regulated my cat's liver function. He is almost 19 and has taken this product for 6 yrs and is doing well.

Best price by Francyn from St-Cesaire03/02/2012

Even my veterenean have your adresse now

Makes a Difference by Leesee10/30/2011

My geriatric kitty has been on Denosyl for the past four years and it has continued to make a positive difference in her liver enzyme values. The pills are easy for her to swallow and never seem to cause any sort of stomach upset as long as she takes them with a little bit of wet food. I highly recommend this product.

Dog Meds by BichonLover09/23/2013

I always get my Denosyl, which has been helping her liver for years, from Entirely Pets. They send fast and are usually correct. Once, when they sent the wrong dosage for one box, they promptly sent another one to me and told me I could donate the other box to my vet.

Affordable by Snoopy from PItman, NJ09/04/2014

My Dog Schultz(Dachshund) has liver, gall bladder, Cushings, etc. This medicine was prescribed for him by his Dr. One box at the Vets office cost what 3 boxes your company charges. Schultz has been on this for 2 years and when blood work is done, 3x a yr, this supplement keeps his levels perfect.

liver disease in miniature dachshund by betsyjo from Dayton, ohio01/04/2014

Betsy is a miniature dachshund, she has been on phenobarbital for seizures most of her life. She is almost 15 years old. We discovered she had liver disease shortly after she turned 14, Vet attempted to remove her from Phenobarbital with out success. However denosyl did lower her liver enzymes a significant amount. We had to put her back on phenobarbital after a major seizure. and her enzyme level once again rose but denosyl is keeping numbers from getting higher. She is perky and eats foods for her liver health.We did not want to lose her yet. but mostly do not want her to suffer. denosyl has worked wonders for her.

by from 11/28/2012

This product has been a life saver for my little dog. The customer service has been very helpful as well. I was having trouble with a Groupon and your staff was very good at making it work!!!

Chehalis, WA by from Thanks"


Necessary for dogs with lliver disease by Charlie10/18/2011

This product was recommended by my dogs veterinarian. She has liver disease and this is a great product to help reduce the changes of further liver damage.

Good value by Cocoa03/13/2013

This product provides additional protection to my pet because she takes phenobarbital for seizures.

denosyl by drjk from new jersey06/28/2013

so far very satisfied with both product and pricing...

Never received Product by Popeye12/24/2012

I can't give a review since the company never sent me the product.

what I expected by quiltlady07/21/2012

The item was as advertised and arrived in a timely manner. Thank you.

denysol by pet lover07/17/2013

helps my dog able to live a normal life. Easy to administer.

So Grateful for Entirely Pets! by Terri from Idaho10/25/2012

I have been a customer of Entirely Pets for many years. In comparing prices, they always come out the winner. I receive orders promptly. Their customer service is excellent and they are always available to answer questions. I highly recommend Entirely Pets!

Beats waiting at the vets office! by Misha10/19/2011

Order received quickly and much less money than the vets (and I didn't have to wait around for them to find it). I'll get my pet's supplements here in the future.

by from 08/07/2012

This is a good product at an excellant price. Unfortunately the manufacturer is behind on delivery of this as well as Denamarin.

the by best from youEntirelypets


Commitment Kept by Jim K03/08/2013

The order was correct and timely ... that's what counts!

Angel feels great! by cheriberry from Grass Valley, CA02/08/2014

Purchased this product on the advice of my vet. My dog is peppy and very happy.

Improved liver values by Dee01/07/2009

My dog Teddy has been on Denosyl for the last six years after being diagnosed by our Vet with poor liver values. His values improved to normal only after three months using the Denosyl. I started buying Denosyl from Entirelypets since it was almost half of what I paid the Vet for it. I kept him on one pill a day for maintenace and just recently increased him to two pills a day after a recent test showed his liver values were slightly elivated. After increasing to two pills a day his values are normal again. Teddy is now 16 going on 17 this year and I think the Denosyl has helped him live a longer, healthier life.

Wonderful by GW4407/30/2013

A pleasure doing business with this Co., very fast shipping and great prices, buy often, thankyou!

improved liver function by Julie02/29/2008

My cat William had a poor prognosis when he was diagnosed with liver problems, cause unknown. He was immediately put on Denosyl and Marin, and after 6 months his liver values are almost normal!

Easy effortless purchase by Hatlover from upstate, NY02/26/2013

So happy to find Denosyl at Entirely Pets. Saves me time and money instead of a trip to the vet. Love having it delivered right to my door.

Best Service You Could Ask For by Buddy from Central New Jersey05/30/2012

The product was delivered in a short time, the packaging and product was the same as I get at the Vet for half the cost. I am extremely satisfied with Entirely Pets.

DENOSYL by DEBBIE10/31/2011

This medicine was prescribed by my veternarian for my cat. Its works great. The vet was charging me $30.00 for a one month (30 Tabs) Supply. By ordering Denosyl from Entirely Pets I can get a 90 day supply (90 Tabs)for $51.99. which equals $17.33 per month instead of $30.00 the vet was charging. It is the exact same medicine that I was getting from the vet. I highly reccomend order from Entirely Pets. Items are delivered very quickly and are exactly what you ordered. I have been ordering for a while from them and I am highly satisfied.

Denosyl by Teddy12/10/2012

I never received this order. Was told it was on backorder.

by from 11/06/2012

price wise you can't beat this. my dog is doing so good on this and he is looking great.

is by i from canthe


Great company to do buniness with by Vicki04/19/2012

As always, great price for a great product! Will order again.

by Dusty07/22/2013

Wonderful, quick shipping, great company to deal with

by from 06/25/2013

Denosyl which is Sam-E only is a great product, especially as 100 mg size is not possible to buy in human form.

Entirely by Pets from sellsThe


by from 10/11/2011

Our 10 year old cat has had a liver problem for over 5 years. I usually buy 3 to 6 months worth of Denosyl for her. The costs are HALF what the vet wanted to charge for the exact same thing. Sales are always used when buy the products. Shipping in within a reasonable time frame too.

Pets by to from allI


Denosyl for cats by cat owner03/15/2013

My vet prescribed Denosyl for my 13 year old cat with chronic pancreatitis. As far as I can tell, it is helping maintain her pancreatitic enzyme level at a normal level. She is no longer experiencing pain from elevated numbers.

Just like the one at the vet by danhart10/25/2012

I bought Denosyl from Entirely Pets and I paid less than half what I pay at the vet for the exact same thing!

Great Purchase by Flshirl from Port St. Lucie, FL02/22/2013

Entirely Pets not only had the Denosyl for small dogs that I needed for my little Yorkie available, but the shipping was very fast as well. I am very pleased with this transaction and will order from this store again.


Questions and Answers

Denosyl®  for Dogs Professional Line (30 Chewable Tabs)Denosyl® for Dogs Professional Line (30 Chewable Tabs)
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Denosyl for small dogs and cats (30 tablets) 90 mgDenosyl for small dogs and cats (30 tablets) 90 mg
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6 Pack Denosyl for small dogs and cats (180 tablets) 90 mg6 Pack Denosyl for small dogs and cats (180 tablets) 90 mg
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Denosyl for dogs over 25 lbs (30 tablets) 225 mgDenosyl for dogs over 25 lbs (30 tablets) 225 mg
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