Denosyl S-Adenosylmethionine Chewables (30 Tablets) 225 mg by. Nutramax Laboratories, Inc. is a nutritional supplement that helps minimize a variety of liver problems in dogs. It has also been shown to improve liver health and function by protecting and repairing liver cells. It is recommended to improve hepatic glutathione levels in dogs. For optimal absorption, give your dog Denosyl on an empty stomach, at least an hour before feeding.
CANINE DENOSYL ADMINISTRATION GUIDE
Body weight (lbs)
Total daily administration
and tablet size
Up - 6
7 - 15
16 - 30
31 - 45
46 - 60
61 - 75
76 - 90
91 - 105
The number of tablets can be gradually reduced or may be increased at any time at the recommendation.
Denosyl, a nutritional supplement, is the pure and stabilized salt of S-Adenosylmethionine for veterinary use only. It is the only brand researched in medical trials for veterinary use in dogs and cats.
S-Adenosylmethionine is an endogenous molecule synthesized by cells throughout the body and is formed from the amino acid methionine and ATP. It is an essential part of three major chemical pathways in the body.
Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidants that protects hepatic (liver) cells from toxins. A study found that low liver glutathione concentrations are common in dog and cats with decreased liver function.
For optimal absorption, tablets should be given on an empty stomach, at least 1 hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulties administering tablets to their pets, this medication maybe disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach in cats, but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the table into the stomach. Denosyl 9- mg tablets are ideal for cats because of their small size.
Storage: Store in a cool, dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.
What does the liver do?
The liver participates in many activities within the body. It helps the digestion of food through production of bile and helps change digested foods into substances used by the body for energy and growth. The liver also helps process some medications into material(s) that can be used by the body; the liver may assist in eliminating medications from the body once they have had their effect. The liver stores vitamins and minerals and works with sugar (carbohydrates, glucose), fats and proteins. It also helps maintain proper blood clotting and removes many body toxins from the blood. Without proper liver function, the pet's health is compromised.
Because it does so much, the liver may be subject to many things: injury, both direct and indirect, infection, and toxicity. Some of the signs and symptoms of compromised liver function in pets may include: weakness, vomiting, poor appetite, and/or seizures. But if there is mild or early stage liver compromise, the pet can appear normal. If you notice any of these symptoms or your pet is just acting differently, you should contact your veterinarian. Many veterinarians run screening tests for middle aged and older patients during the annual examination to ensure that organ function is normal.
My dog needs to be on this medication for life, so it is only natural I am looking for the best quality and price. I checked this medication out with my local vet and I got the thumbs up.
EntirelyPets had the best price and the service they provide is exceptional. They stand behind their products and provide quick delivery.
Believe me, I have put them through the test for delivery and they came through.
Dog loves it! by Barney's Mom03/12/2009
I've been giving my 16 year old dog Denosyl for a couple years now. As long as his blood tests show it's working I will continue... however there was one thing about the denosyl tablets that I loathed, it was their sizel It's an orange horse pill. Which means I need to hide it in a piece of food to get him to take it. Of all the pills he takes per day this and Atopica are the two I dreaded because they can't be easily disguised. He'd wised up to what I was doing and work the pill out of the food and drop the pill to the floor. I kept changing what I hid it to fool him but he soon figured that out as well. Some times he was so obstinant I'd have to stick it in his throat which stressed us both out. Those were the times when I'd think to myself, WHY can't they make this easy on us and just make this pill chewable! Well they finally did and I am greatful for it. We're just about done with the first bottle so I can say with confidence that this pill must taste good because my finicky dog loves it and has never spit it out. It costs more per pill than the original but it makes life a little bit easier so for me it's worth it. Now if only Atopica did the same I'd be a happy camper. I'll never go back to the non-chewable, this is just what I wished for.
Fast Service by Whatnot10/17/2011
Ordered online and within 2 days the shipment arrived. It was really fast. Good job.
by from 04/10/2012
Our two blue heelers both had poor liver funtion. Since starting both on Denosyl, both dog's liver function is now within normal range. Vet says they need to continue on Denosyl indefinitely.
Nancy by San Angelo, TX from Great
Improved liver function
Great Product by izzyb03/01/2012
My cairn, Tait, had a tumor removed from her liver. Successful surgery, and my vet recommended Denosyl on a daily basis. She is like a puppy and she is 11 yrs young. Thank you to everyone and finding this product.
Effective and easy to administer by Emily's buddy from Baltimore, MD11/05/2011
My vet recommended this product because the SAM-e in Denosyl would help to normalize my dog's liver functions. Other products contained additional ingredients that upset her stomach. She tolerates Denosyl very well and, as an additional benefit, she is happy to chew these tablets up as if they were candy! Most importantly, her liver functions are almost normal now.
Easy To Give Liver Protection by Bob from Shreveport, LA10/20/2011
This product was prescribed by my vet for Heidi, a thirteen year old Dachshund with acute pancreatitus. More time will be needed to determine if the medication is working. The chewable form is much easier to give than the bad tasting tablet. Heidi thinks it is a treat.
Great-Tasting Meds by Auzzie's Mum from Los Angeles02/17/2012
Very pleasing taste (according to my dog) --- just like treats!
A Good Value by RC from Phoenix, AZ12/16/2011
I am very happy with this product. Our little Wire Hair enjoys them as if they were a treat. Its hard to tell how well they work in keeping his liver healthy we don't have another checkup from the vet due for a while. I read it is as effective as Sam-e or a Vet prescribed formulary.
Denosyl by ridgerunner10/15/2011
My dog is on this medication for the rest of her life. I started out paying $45 per 30 tablets. Then $37. Found EntirelyPets and paid $23 per 30 tablets. Thought I would try it out and when I got the shipment they were close to expiration date but would be used before then and was no problem for me. I will continue to order from EntirelyPets for this supplement if the price stays low.