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6 Pack Denosyl for dogs over 35 lbs (180 tablets) 425 mg

Item Number: DENO425MG6PK
Regular Price: $357.00Sale Price: $258.99
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#1 Veterinarian Recommended Liver Denosyl is a nutritional supplement that helps minimize a variety of liver problems in dogs and cats. It has also been shown to improve liver health and function by protecting and repairing liver cells. It is recommended to improve hepatic glutathione levels in dogs and cats. For optimal absorption, give your dog or cat Denosyl on an empty stomach, at least an hour before feeding.

Body weight Total daily administration and tablet size
35 to 65 pounds (16 - 29.5 kg) One tablet of 425 mg
66 to 120 pounds (30 - 54.5 kg) Two tablets of 425 mg
Over 120 pounds (30 - 54.5 kg) Three tablets of 425 mg

The number of tablets can be gradually reduced or may be increased at any time depending on the pet's needs.

Usage Information

Ingredients: S-Adenosylmethionine

Denosyl, a nutritional supplement, is the pure and stabilized salt of S-Adenosylmethionine for veterinary use only. It is the only brand researched in medical trials for veterinary use in dogs and cats.

S-Adenosylmethionine is an endogenous molecule synthesized by cells throughout the body and is formed from the amino acid methionine and ATP. It is an essential part of three major chemical pathways in the body.

Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidants that protects hepatic (liver) cells from toxins. A study found that low liver glutathione concentrations are common in dog and cats with decreased liver function.

For optimal absorption, tablets should be given on an empty stomach, at least 1 hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulties administering tablets to their pets, this medication maybe disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach in cats, but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the table into the stomach. Denosyl 9- mg tablets are ideal for cats because of their small size.

Storage: Store in a cool, dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.

What does the liver do? The liver participates in many activities within the body. It helps the digestion of food through production of bile and helps change digested foods into substances used by the body for energy and growth. The liver also helps process some medications into material(s) that can be used by the body; the liver may assist in eliminating medications from the body once they have had their effect. The liver stores vitamins and minerals and works with sugar (carbohydrates, glucose), fats and proteins. It also helps maintain proper blood clotting and removes many body toxins from the blood. Without proper liver function, the pet's health is compromised.

Because it does so much, the liver may be subject to many things: injury, both direct and indirect, infection, and toxicity. Some of the signs and symptoms of compromised liver function in pets may include: weakness, vomiting, poor appetite, and/or seizures. But if there is mild or early stage liver compromise, the pet can appear normal. If you notice any of these symptoms or your pet is just acting differently, you should contact your veterinarian. Many veterinarians run screening tests for middle aged and older patients during the annual examination to ensure that organ function is normal.

Customer Reviews

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4.84 rating based on 55 reviews
Denosyl for Dogs by robfitzh03/06/2013


Denosyl by Sick of waiting from So Cal06/23/2013

Hard to review a product that was back-ordered to MID JUNE when I ordered it on May 26 and as of June 23 is still showing as a 4-6 week backorder. But hey no worries its only my dog's ailing liver

Save Money by Jan07/11/2014

Purchasing Denosyl from Entirely Pets has saved us quite abit of money. Our dog is elderly and will probably be taking this product for the rest of her life. To purchase it from the Vet would cost us so much more.

by Ana from Brazil04/29/2013

My two scothish terriers take denosyl since 2011 and since than, their liver enzimes are stabilized. Their life quality is much better now.

Great product by Zwoman09/16/2014

Great product, great service and super fast shipping!!!

Denosyl by Danook03/19/2014

I give it to my my dogs for many years now and it help liver function and really less expensive than to buy it at the veterinary clinic!

Best Price-Product Works by granee from Apple Valley California12/05/2012

My dog has been using this product for several years. He is almost 16 and his liver problem has not gotten worse!

Worst Service Ever by Unhappy from Naples, florida06/26/2013

Ordered this back on 5/29/13. It's now 6/26/13. Still waiting. Would not recommend anyone to do business with Entirelypets.com.

Keeping him going by Deanie from Whitesburg, Ga.09/17/2013

Lupus treatment almost destroyed my pup's liver. Denosyl has gotten him back and his liver tests are now normal. thank you denosyl

Difficult.... by robfitzh06/22/2013

Products not yet delivered as still on back order......again - second time this has happened! Please sort this out

Lifesaver for My Dog by Jen from Middleburg, PA01/16/2015

My dog suffers from Copper Storage Disease which affects his liver. His ALP value was steadily increasing for the past year and nothing we tried would take it down. After 3 months of taking this, my dog's ALP and ALT liver values went down. I wish I tried it sooner. Thank you Entirely Pets for providing the product at a more affordable price than directly from the vet office.

by Lablover06/01/2013

I still don't have the product. It was on backorder and I have not received word when it may be in stock. When I called, I was told "next week". That week has come and gone and no word when it may be shipped. When I have received it in the past, the product was excellent.


Questions and Answers

Denosyl for dogs over 35 lbs (30 tablets) 425 mgDenosyl for dogs over 35 lbs (30 tablets) 425 mg
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