Denosyl is a nutritional supplement that helps minimize a variety of liver problems in dogs and cats. It has also been shown to improve liver health and function by protecting and repairing liver cells. It is recommended to improve hepatic glutathione levels in dogs and cats. For optimal absorption, give your dog or cat Denosyl on an empty stomach, at least an hour before feeding.
FELINE AND CANINE DENOSYL ADMINISTRATION GUIDE
Total daily administration
and tablet size
Up to 12 pounds (5.5 kg)
One tablet of 90 mg
13 to 34 pounds (6-15.5 kg)
One tablet of 225mg
35 to 65 pounds (16 to 29.5 kg)
One tablet of 425 mg
66 to 120 pounds (30 to 54.5 kg)
Two tablets of 425 mg
Over 120 pounds (54.5 kg +)
Three tablets of 425 mg
The number of tablets can be gradually reduced or may be increased at any time depending on the pet's needs.
Denosyl, a nutritional supplement, is the pure and stabilized salt of S-Adenosylmethionine for veterinary use only. It is the only brand researched in medical trials for veterinary use in dogs and cats.
S-Adenosylmethionine is an endogenous molecule synthesized by cells throughout the body and is formed from the amino acid methionine and ATP. It is an essential part of three major chemical pathways in the body.
Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidants that protects hepatic (liver) cells from toxins. A study found that low liver glutathione concentrations are common in dog and cats with decreased liver function.
For optimal absorption, tablets should be given on an empty stomach, at least 1 hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulties administering tablets to their pets, this medication maybe disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach in cats, but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the table into the stomach. Denosyl 9- mg tablets are ideal for cats because of their small size.
Storage: Store in a cool, dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.
What does the liver do?
The liver participates in many activities within the body. It helps the digestion of food through production of bile and helps change digested foods into substances used by the body for energy and growth. The liver also helps process some medications into material(s) that can be used by the body; the liver may assist in eliminating medications from the body once they have had their effect. The liver stores vitamins and minerals and works with sugar (carbohydrates, glucose), fats and proteins. It also helps maintain proper blood clotting and removes many body toxins from the blood. Without proper liver function, the pet's health is compromised.
Because it does so much, the liver may be subject to many things: injury, both direct and indirect, infection, and toxicity. Some of the signs and symptoms of compromised liver function in pets may include: weakness, vomiting, poor appetite, and/or seizures. But if there is mild or early stage liver compromise, the pet can appear normal. If you notice any of these symptoms or your pet is just acting differently, you should contact your veterinarian. Many veterinarians run screening tests for middle aged and older patients during the annual examination to ensure that organ function is normal.
DISCLAIMER: The results described on the testimonials on this site, are the individual experiences and personal opinions of those who have purchased and used the products. These testimonials are not intended to make any claims that the products can be used to diagnose, treat, mitigate, cure or prevent any disease or medical condition.Click here to see all reviews
4.82 rating based on 78 reviews
denosyl 225 mg & hexedine soap by Judy from Oak Lawn, IL10/23/2012
You have the best price on both the denosyl and hexedine. You have prompt service as far as the shipping. I am more than pleased and will continue to use you
by from 06/28/2013
My dog, Molly, was diagnosed with liver disease over three years ago. She was not expected to live two years.
with by others from andThis
the by best from price."Entirely
by from 05/16/2014
Product exactly as described...inexpensive and shipped fast A+++++
little by boy from Timmy,We
denosyl by none04/29/2013
excellent low price, on time delivery as promised and product was in correct manufacturers packaging. will absolutely use ya'll again.
denosyl for liver by Moongoon03/03/2014
My dog was put on this by our vet many years ago when he had to take phenobarb for seisures. It is to protect his liver.
Great Product by Tsmom01/30/2014
My dog has a liver shunt and this product is much cheaper than the price that his vet charges. Thank you for such a great product.
Save my Dog by Christine01/17/2008
Denosyl saved my dogs life. My Sheltie is epileptic and the meds for his seizures damaged his liver. He was a very sick dog but my Vet suggested Denosyl and Marin and within a week I noticed major improvement. In a months time his liver fuction is back to normal and he feels great! I highly recommend this product.
Denosyl by Rose12/09/2012
My Beagle's liver numbers were 4 times out of normal range and became normal after using this product daily for a number of months. Seems like she will have to take it for the rest of her life to keep the numbers in a normal range.
by from 06/21/2013
I ordered this online because I was in a rush and to get to the vet would, one, take forever, and two, be more expensive. I ordered the Denosyl on here and had it within a few days. It was a little cheaper and saved me time.
RTD4 by from Thank
Great 1st purchase experience by Laurie from Marysville, CA04/25/2012
Great price compared to other sites and quick delivery. Will definitely make future purchases from Entirely Pets.
Amazing Product by Mona from Ellijay, Ga.09/24/2014
Denosyl for dogs saved my little Ginger. Great product. I would recommend it to anyone who has a pet with liver disease.
The service is prompt and the prices are good and the drug companies are known to me.
Only GOOD things to say about your company!
Great product by Vinny from Las Vegas, NV10/30/2012
Is greatly helping to keep my dog's liver functioning well.
Wonderful Lifesaving Product by Underthemattress from Northwestern US04/15/2012
Our 13 yr. old female mini schnauzer has been into emergency vet 4 times now for pancreatitis related issues. Since starting Denosyl and Marin, her liver values have greatly improved and no more tummy issues. Highly recommend and we will in all probability keep her on this for the rest of her life.
missing product by ken from graham washington04/27/2014
i ordered denosyl and you did not have marin in stock .so i never recieved the marin. you said it was backordered, i am still waiting. Ken
by from 05/23/2013
When my vet told me my precious pet needed this medication for her liver condition and what the charge was, I was floored.
my by beautiful from dogYou
Helps my dog's liver problems by Mel from Edmond, OK09/05/2014
My dog had an abnormally high liver enzymes reading at her last annual physical. After taking Denosyl for several months, her latest checkup showed her liver enzyme levels were much lower.
Denosyl at HALF the price! by RTDfour08/30/2013
This product is a liver function pill that our vet requires our terrier to be on. At the vet it costs us over $60 and through EntirelyPets we get it at HALF that price! When you have older dogs that take several medications, it adds up. This site saves us a lot of money! THANK YOU!!
Best purchase by Shelley10/11/2011
Excellent customer service and prompt delivery of brand name products. Prices very competitive also. Explanations of product very informative and clear regarding doasge and usage.
Helps the old girl hold her own by LikesArt from Atlanta07/28/2014
My 12-year-old rat terrier has been taking this for years per the vet's orders. It seems to be helping keep her pancreatitis stable.
Rejuvenates you best buddy by Hootenanny01/13/2012
My pal had three bouts of pancreatitis and elevated liver readings that were off the chart. Even though it's difficult to get my sweetie to have an empty stomach (which is needed to take this medicine), it's been a life saver. Thank you, Denosyl.
Used in conjunction with Prednisone and Actigal for feline pancreatitis. So far lower GI symptoms have stopped, however only half-way through entire course of treatment.
Denosyl 225mg Tablets by Phyllis from Trussville, Alabama09/13/2011
I am so thankful for Entirely Pets. My dog had her gallbladder removed and had to start using Denosyl daily. Two different area vets wanted $80-$90 for this same product. When I found out I could order this from Entirely Pets, I have been very satisfied since my first order. They were efficient, cost effective and quick to send it through the mail. I would recommend Entirely Pets to anyone who wants great service and reasonable prices for their products.