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Dermal-Soothe Anti-Itch Spray for Dogs & Cats is an amazing way to relieve itching and heal dry, sensitive skin on dogs and cats.

 You'll love how effectively this skin solution heals your pets and how easy it is to use. Simply apply this shampoo topically as one would during a normal bath and notice the improvements to your pet's skin and coat.

Dermal Soothe Anti-Itch Shampoo for Dogs & Cats (1 Gal)
Dermal Soothe Anti-Itch Shampoo for Dogs & Cats (1 Gal)

($185.99)  $142.99
Dermal Soothe Anti-Itch Spray for Dogs & Cats (12 oz)
Dermal Soothe Anti-Itch Spray for Dogs & Cats (12 oz)

($20.99)  $15.99
Micro Pearls Dermal-Soothe Anti-Itch Cream Rinse (8 oz)
Micro Pearls Dermal-Soothe Anti-Itch Cream Rinse (8 oz)

($14.99)  $11.49
Dermal Soothe Anti-Itch Shampoo for Dogs & Cats (8 oz)
Dermal Soothe Anti-Itch Shampoo for Dogs & Cats (8 oz)

($18.99)  $13.99
This item is Currently Out of Stock and Should be Shipped 4-6 Weeks.

Dermal Soothe Anti-Itch Spray for Dogs & Cats (1 Gal) is a remarkable breakthrough in animal health care technology. Dermal-Soothe™ Anti-Itch Shampoo contains itch relieving Pramoxine HCl and NOVASOME® microvesicles designed to deliver long-lasting moisture factors to the hair and epidermal layers in a luxurious shampoo. The result is an itch relieving shampoo that leaves your pet a coat that is soft, supple and lustrous. Safe for use on dogs, cats and horses.


A luxurious conditioning shampoo for relieving itching and dry skin. Excellent for use on animals with normal, dry or sensitive skin.


1% Pramoxine HCL in a concentrated shampoo base with Novasome microvesicles, Colloidal Oatmeal and Skin Respiratory Factor.

4.80 rating based on 5 reviews
Featured Reviews for Dermal Soothe Anti-Itch Spray for Dogs & Cats (12 oz)
regular use by Delilah from Las Cruces, New Mexico09/02/2013

We used this product every two days to relieve itching on a dog with chronic skin allergies. Have used for over 4 years with great results.

Perfect For Itchy Terrier by Annie11/24/2012

Love this spray. Our very sensitive and alergy - prone terrier appreciates the relief and we like spray's pleasant smell. Takes care of itchiness between our weekly bath time.

itching by China08/07/2014

My dog has allergies with grass. She is itching on her feet and back. This med is working great it helps a lot . I well continue to use for her comfort.

DON'T BUY IT by mar03/21/2014

I am a Veterinarian not in practice; this product is slimy, does NOT provide any itching relief, and entirely pets makes you pay the shipping fees for returns - go someplace else, and look for Dermacool by Virbac.

Severe skin allerfies by Delilah Lab06/23/2012

Have used this product 3X weekly for over 5 years to reduce itching for our Labs severe skin allerigies. Has done as well as can be expected and reduced the number of infections and constant itching significantly.

Wonderful by Claudia Pines09/16/2009

This product smells so good too - I have (3) chihuahuas - makes their coat soft - use it often - will buy again.

Featured Reviews for Micro Pearls Dermal-Soothe Anti-Itch Cream Rinse (8 oz)
Wonderful stuff by Kirby the pug09/17/2011

Kirby our pug has very itchy skin, and adding this to his bath has been a good thing! It smells wonderful and really soothes the skin and softens his hair. We are very pleased with it!

Outstanding companion to Dermal-Soothe Shampoo by Noelle08/23/2013

If you have read my review of Micro Pearls Advantage Dermal-Soothe Anti-Itch Shampoo, you know that I strongly recommend this product as well. It is the companion product to the shampoo. I have used both products for eight years, and these products are exceptional--the ONLY products I will use! My dog's coat is not as dry; the scent is clean and pleasant; and being a black and white dog, his black glistens like a prism, and his white is the color of a first snow. I always receive compliments on the shine and quality of his coat. And, with continued use, the fourth week after his bath, his coat continues to look as pristine as the day he was bathed. I hope that if you try these two products you will be as impressed as I am.

by Nads02/09/2013

Ordered this before I got the name of another product, was told I could return if package was unopened. Ordered the item I entended to order in the first place both were delivered to my PO Box and I had no idea which was which......had to open so NO RETURN.....you guessed it I opened the package that contained this. We tried it.....and did not help with my dogs itching. Will order from Entirelypets.com again just not this product.

Left our pup so soft by Trishkers10/31/2011

Our 4 year old female Havanese suffers from allergies. This product left her so soft and smelling so clean. She did not itch after her grooming and looked like a totally cute ball of cotton. We will continue to use this after each grooming!

Sebboreah by Bsquared from Ridgefield, CT01/20/2014

This is the best product I have found to control my Scotties severe Sebboreah. He was scratching to death before, now it appears at least controllable with out the terrible crusts and scabs all over his underside.

Dermal Soothe by Cheechie from Pittsburgh, PA03/31/2012

Great Product for dry skin and allergies.

Featured Reviews for Dermal Soothe Anti-Itch Shampoo for Dogs & Cats (8 oz)
Great shampoo and conditioner by MICHELE from Lutz. FL03/16/2014

This shampoo and conditioner works great for my Lab, who has a lot of allergies and is on bi weekly injections. It's soothing to him and it's scent is good enough for us to use on ourselves. Great product. Just make sure to leave on your pets coat 10 mins or so. Very happy customer and pet.

Wonderful Product by pugluver from Richmond, VA10/25/2013

Great product. Used Relief shampoo, but didn't work as well as Dermal-Soothe. Following directions and leaving on for about 10 minutes is essential. Doesn't lather up a lot, but works great. Would highly recommend.

Contains dangerous chemicals by 3DogMom04/02/2014

I did NOT use and returned this product as the directions state that gloves need to be worn and there is a WARNING label stating that "This product contains chemicals known to the State of California to cause cancer." YIKES! No way I want this stuff in my house let alone on one of our beloved dogs!

The ONLY shampoo to use! by Noelle08/23/2013

Not long after I adopted my dog, I realized that ordinary pet store shampoo would not do. My veterinarian recommended this shampoo, and its companion cream rinse, and that is all we will ever use! His skin is not dry; he does not itch; the scent is pleasantly clean; and, being a black and white dog, his black richly glistens, and his white is the color of fresh snow. I am always receiving compliments on the condition and color of his coat. I have been using this product for eight years, and honestly, it is the best. I hope that if you try it you will be as impressed as I am.

Poor Service from Entirely Pets by Sally05/06/2014

While the shampoo was fine - delivery from Entirely Pets was very slow and then the delivered product had a quick turn around expiration date (4 months) on it. I was very disappointed with Entirely Pets.

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