EntirelyPets Online Pet Supply Retailer
Home > Health and Nutrition > Flea and Tick Medicine & Supplies > 

Advantage Flea Control for Dogs

Advantage Flea Control for DogsAdvantage flea control for dogs works fast on fleas. Advantage breaks the flea life cycle by killing flea larvae. Advantage can be used on puppies as young as 7 weeks old. Also, it is safe for dogs that are pregnant or nursing. Advantage is water-resistant, so it kills fleas even after shampooing and exposure to rain. Help keep your dog protected, buy Advantage Flea Control today.

Also Try: Advantage for Cats and FURminator.



4 MONTH Advantage Green: For Dogs under 10 lbs
4 MONTH Advantage Green: For Dogs under 10 lbs

($49.99)  $40.99
6 MONTH Advantage Flea Control Green: For Dogs under 10 lbs.
6 MONTH Advantage Flea Control Green: For Dogs under 10 lbs.

($69.99)  $52.99
12 MONTH Advantage Flea Control Green: For Dogs under 10lbs.
12 MONTH Advantage Flea Control Green: For Dogs under 10lbs.

($132.99)  $103.99
4 MONTH Advantage Flea Control Teal: For Dogs 11-20 lbs.
4 MONTH Advantage Flea Control Teal: For Dogs 11-20 lbs.

($78.25)  $57.59
4 MONTH Advantage Flea Control  Red: For Dogs 21-55 lbs.
4 MONTH Advantage Flea Control Red: For Dogs 21-55 lbs.

($54.99)  $39.99
4 MONTH Advantage Flea Control Blue:  For Dogs over 55 lbs.
4 MONTH Advantage Flea Control Blue: For Dogs over 55 lbs.

($106.33)  $78.29
Advantage Green kills fleas on dogs fast. Advantage kills 98% of fleas within 12 hours and continues to work for up to one month per application. It also breaks the flea life cycle by killing flea larvae. Advantage can be used on puppies as young as 7 weeks old. Also, it is safe for dogs that are pregnant or nursing. Advantage is water-resistant, so it kills fleas even after shampooing and exposure to rain. Advantage is applied between the shoulder blades on dogs.
Effective Flea Control . . . No Prescription Required!
  • Guaranteed US EPA approved.
  • Contains imidacloprid, the fastest flea preventive, which works within 12 hours
  • Long-lasting Over-The-Counter formula keeps working for up to 4 weeks
  • Easy-squeeze tube for easy application.
  • Water-resistant formula stays strong through baths and rain
  • Activity of imidacloprid against fleas
    When a flea is exposed to imidacloprid on a treated pet, the compound is absorbed through the insect's intersegmental membrane. Here, the compound comes into contact with the flea's nervous system. Imidacloprid then acts inside the synapse of the insect to disrupt transmission of the nervous impulse. Imidacloprid binds to post-synaptic nicotinic receptor sites inside the synapse, essentially "locking" the receptor in the open position thus hyperstimulating the cell. As this occurs throughout the nervous system, it leads to death of the insect. Furthermore, imidacloprid is highly selective in its activity. It only binds to insect nicotinic receptor sites, showing virtually no affinity for mammalian receptor sites. As an analogy, one may think of a lock and key, where the insect nicotinic receptor site is the lock and imidacloprid is the key. Imidacloprid only "fits" the right "lock," and does not fit similar receptor sites found in mammals.

    Why killing flea lavre is important
    Flea larvae live in the dog's environment on bedding, carpeting and anywhere the dog regularly sleeps or plays. By killing flea larvae in the dog's environment, imidacloprid kills potentially re-infesting fleas at the source, before they have a chance to reproduce to infest the pet and the home. This larvicidal activity in the environment, combined with the rapid adulticidal activity on the pet, eliminates existing flea infestations quickly and prevents new ones from developing, all without the use of environmental foggers, sprays, or insect growth regulators.

    Larvicidal activity
    Imidacloprid is the premier flea control product, in large part, due to its unsurpassed adulticidal activity. However, imidacloprid also possesses significant larvicidal activity. In fact, Advantage, ® and now K9 Advantix, ® are the only flea adulticides that can make a larvicidal claim.

    How imidacloprid kills flea larvae in the environment
    Once K9 Advantix ® is applied, both active ingredients (imidacloprid and permethrin) spread across the body. Imidacloprid, in particular, spreads rapidly. During this process, imidacloprid forms very fine particles that bind with the superficial lipid layer on the skin surface. This lipid material is slowly shed off of the animal, via the normal replenishing activity of the epidermis. This "dander," made up of bits of epidermal cells, lipid, hair fragments and such, also contains imidacloprid. Thus, the treated dog, in essence, treats its own environment. As imidacloprid is an extremely potent compound (i.e., very small amounts kill fleas and flea larvae), sufficient amounts are deposited to effectively kill flea larvae in the pet's surroundings.

    Inhibition of flea biting
    Studies conducted in Germany by Dr. Heinz Mehlhorn also demonstrate that imidacloprid possesses significant anti-feeding activity, and fleas that jump onto an imidacloprid-treated dog stop feeding in 3 to 5 minutes. Additional studies, conducted by Dr. Michael Rust at the University of California at Riverside, confirmed that imidacloprid demonstrates significant anti-feeding activity, even at very low doses. These results are significant as it is the feeding activity of fleas that elicits an allergic condition known as flea allergy dermatitis.

    Activity of imidacloprid against ticks
    The highly specific mode of action of imidacloprid makes it an ideal compound for insect control. However, it does limit its utility against ticks and mites because they are arachnids (the same class as spiders) rather than insects. Research has shown that imidacloprid does not bind as well to arachnid receptors as it does to insect receptors. For this reason, imidacloprid is not utilized as a stand-alone ingredient for canine tick control. Rather, its limited activity against ticks is best exploited to enhance the efficacy of other compounds, permethrin in particular.
    4.78 rating based on 32 reviews
    Featured Reviews for 4 MONTH Advantage Green: For Dogs under 10 lbs
    by Becka10/19/2011

    This product worked excellent. My puppy stopped scratching. I have not found fleas or fea dirt on her since. I'm in my second month treatment on her. So far, excellent product!

    Caused major problems in 2 small dogs by Nanci from SF Bay area07/27/2010

    Even though vets say this is safe, it is still and insecticide and it caused my 3 lb. chihuahua to have bubbling and oozing skin on her back and hair loss where I put 1/2 of the dose of Advantage. She had to get a steroid shot and an antibiotic. My other dog, a yorkie, had a severe immune reaction which triggered a neurological disease of her brain, GME. Now she has to be on steroids and chemo for almost 2 years!! I'm not taking any chances with my small dogs, it is too risky!!

    Best Flea Product AROUND by Shawnie01/30/2008

    I have to say that this is the best flea product around. I have tried others and nothing and I MEAN NOTHING. I tried this one day last summer and it is awesome and WORTH EVERY penny. I promote this to everyone I see with a dog. Just try it and you will agree....THANKS

    Featured Reviews for 6 MONTH Advantage Flea Control Green: For Dogs under 10 lbs.
    Best Flea Product AROUND by Shawnie06/11/2008

    I have to say that this is the best flea product around. I have tried others and nothing and I MEAN NOTHING. I tried this one day last summer and it is awesome and WORTH EVERY penny. I promote this to everyone I see with a dog. Just try it and you will agree....THANKS

    Featured Reviews for 12 MONTH Advantage Flea Control Green: For Dogs under 10lbs.
    Best Flea Product AROUND by Shawnie06/11/2008

    I have to say that this is the best flea product around. I have tried others and nothing and I MEAN NOTHING. I tried this one day last summer and it is awesome and WORTH EVERY penny. I promote this to everyone I see with a dog. Just try it and you will agree....THANKS

    Featured Reviews for 4 MONTH Advantage Flea Control Teal: For Dogs 11-20 lbs.
    A must have by Noni10/11/2011

    Great price for this product. Their delivery service is awesome.

    Love It! by Judi06/11/2008

    I have used this product for years. I found Entirely Pets by accident and have now saved $10 off the Vets price. It works great and the flea season started very early this year. I was thankful i could get it online. Thanks.

    Awesome by LZ from Ontario Canada06/28/2013

    This product is fantastic. It would cost twice as much if I went to the vet, and I would have to pay the $85.00 office visit. I will continue to buy from Entirely Pets. Only con-shipment time. It takes at least a week for the product to even get shipped out of the warehouse. If they improved on that, I would have nothing negative to say about the site!

    Best prices !! by wuzzlesnanny from northeastern NY10/13/2011

    I always get my pet products here at " Entirely pets" because they have te best prices and the shipping is very fast and never damaged. I have told many friends and they get alot of their pet needs here to. I recommend this company very highly.

    Featured Reviews for 4 MONTH Advantage Flea Control Red: For Dogs 21-55 lbs.
    Try This! by Kenny Skinner06/11/2008

    Very please with the time of arrival and the results it had on our dog in getting rid of his fleas.

    fleas fleas fleas by kalos from Findlay, Oh06/30/2011

    We bought this for our dog and was not pleased at all. She is still coated in fleas and now have to spend even more money to buy the flea med from the vet and not a store. I do not recommend this product, obviously it did not work.

    Featured Reviews for 4 MONTH Advantage Flea Control Blue: For Dogs over 55 lbs.
    Couldn't Live Without This! by Phyllis from Trussville, AL02/02/2012

    I have been using Advantix for every dog I've ever owned. This is a great product and I have never had problems with fleas, ticks, or mosquitoes. This is a necessity for all of my dogs to have because I want them to enjoy life without those pesky critters. Thanks for the great prices, and your quick delivery service! Your company rocks!

    Advantage by BROBILLE from Birmingham, AL10/18/2011

    When Frontline stopped working and my house filled with fleas, I switched to Advantage. Got rid of the fleas, the price was great, the service was great, and I always get the product before I thought I would. Good, you, Entirely Pets, you get 6 attaboys for your service.

    Best flea prevention by DJ04/04/2012

    Advantage is the best flea prevention for my dog and cats. I've been using it for over 10 years. Safe way to protect your dog without risk to your cat if they play. Once a month for the dog and as needed for my cats. Advantage is the best.

    Thank Dog for Advantage by D. Seaman06/11/2008

    Our outdoor area is suffering through a major flea infestation. Having tried frontline without success, we waited some time before trying Advantage. Worked like a charm.

    by from 07/27/2012



    Related Items
    Allergroom Shampoo by VIRBAC (8oz)
    Allergroom Shampoo (8oz)
    Liver Biscotti
    Liver Biscotti

    Stay Connected

    Copyright 1999 - 2014 EntirelyPets.com - All Rights Reserved
    Sitemap - Privacy Policy - Mobile Site - Contact Us


    CALL US TOLL FREE: 1-800-889-8967