• 6 MONTH Frontline Top Spot Orange: For Dogs up to 22 lbs.

6 MONTH Frontline Top Spot Orange: For Dogs up to 22 lbs.

SKU: 10011
Regular Price: $94.99Sale Price: $81.98
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This item has been manufacturer discontinued. We recommend trying Effitix for Dogs Up to 22.9 lbs. - 6 Months

Temporary Price Reduction! FRONTLINE Top Spot Orange for Dogs up to 22 lbs

Frontline Top Spot Orange for dogs and puppies provides flea and tick protection for at least one month. It is applied topically and each packet has 6 applications providing 6 months of protection.

Effective Flea & Tick Control . . . No Prescription Required!
Kills Fleas

FRONTLINE Top Spot Orange for Dogs 0-22 lbs is a powerful and easy-to-use formula designed to quickly and effectively kill fleas, ticks, and chewing lice. FRONTLINE Top Spot is specially formulated for dogs and puppies over 2 months of age or older, weighing less than 22 lbs. Do not reapply FRONTLINE for 30 days.

Quickly Kills Fleas, Ticks, and Chewing Lice
Kills Ticks

Frontline contains the active ingredient fipronil that effectively targets fleas, ticks and chewing lice. Fipronil collects in the oils of the skin and hair follicles, and continues to be released from hair follicles onto the skin and coat, resulting in long-lasting activity

Waterproof Formula

Thanks to its waterproof formula, FRONTLINE Top Spot won't rinse off when you give your dog a bath or when your dog goes for a swim. The active ingredient in FRONTLINE, fipronil, is stored in the natural oils in your dog's coat, so your pet is sure to stay protected no matter how many puddles he or she tramps through.

Fipronil 9.8%
(S)-methoprene 8.8%
Inert Ingredients 81.4%

This FRONTLINE Top Spot product is EPA approved and registered. It's guaranteed to be the exact same product sold by your Veterinarian. Click here for more information on EPA-approved pet products.

FRONTLINE Top Spot Orange
for Dogs 0-22 lbs
  • Guaranteed US EPA approved.
  • Over-The-Counter topical kills fleas & ticks in under 48 hours
  • Protect against Lyme disease!
  • Easy to apply monthly preventive
  • Per Dose: $10.33
More Info
Got Fleas?

A product guide to flea and tick products.

Flea Facts You Should Know

Interesting flea facts to help your pets be pest-free.

Fleas: Understanding the Enemy

All about fleas and prevention.

FAQ about Fleas/Ticks


Helpful information on Ticks and your pets.

Dog with fleas
FRONTLINE TopSpot for Dogs is Available In:
(0 - 22 pounds)
(23 - 44 pounds)
(45 - 88 pounds)
(89 - 132 pounds)
3 month
6 month
12 month
3 month
6 month
12 month
3 month
6 month
12 month
3 month
6 month
12 month

Usage Info

How FRONTLINE Top Spot Works

Use FRONTLINE TOP SPOT for fast-acting, long-lasting flea and tick control. When you apply FRONTLINE, fipronil, the active ingredient, is stored in the oil glands under your pet's skin. It's then distributed continuously to the skin and hair of your pet through the hair follicles. This way, FRONTLINE provides waterproof, month-long protection against future pests while breaking down the flea and tick life cycles.

Simple Three-Step Application

Applying FRONTLINE TOP SPOT to your pet is an easy three-step process. First, remove the Frontline Top Spot applicator from the child-resistant package and cut or lift off the plastic tab to expose the foil and then peel the foil down. Next, hold the applicator upright and away from your face and body and snap off the tip. Finally, place the Frontline Top Spot applicator tip on the skin between your pet's shoulder blades and squeeze the applicator to apply the entire contents in a single spot onto your pet's skin.

To prevent harm to you and your pet, read the entire label and enclosed directions before each use. Follow all directions and precautionary statements carefully.


To prevent harm to you and your pet, read the entire label and enclosed directions before each use. Follow all directions and precautionary statements carefully. Always point the applicator away from your face, especially your eyes, and wash your hands thoroughly after application. USE ON DOGS ONLY. Do not use on rabbits or other animals.

Weight Dosage
Up to 22 pounds Apply contents of one applicator (0.67 milliliter) once per month
23 - 44 pounds Apply contents of one applicator (1.34 milliliters) once per month
45 - 88 pounds Apply contents of one applicator (2.68 milliliters) once per month
89 - 132 pounds Apply contents of one applicator (4.02 milliliters) once per month
All weights Apply contents of one applicator (0.5 milliliter) once per month



Fipronil is a manufactured insecticide that works on a cellular level on adult fleas and ticks. It seeps into an insect's cells and blocks chlorine molecules from passing through. This stops the nervous system from working and paralyzes the insect.

Fipronil kills adult fleas and ticks on contact or when consumed, and it can be spread from one insect to another.


Because fipronil is so strong, it only needs to be applied once a month to continuously kill fleas and ticks. Once it is applied with an oily liquid to keep it on the skin of your dog, it slowly seeps into the hair follicles and oil glands where the fleas and ticks live.

Main Purpose

To kill adult fleas and ticks.

Active Ingredients % by Weight
Fipronil 9.7%
Inert Ingredients 90.3%
Total 100%

Some animals are sensitive or allergic to the ingredients in FRONTLINE, so be sure to watch for any signs of allergic reaction. If your pet shows signs of itching, restlessness, nausea, lethargy, or breathing difficulty, seek veterinary attention immediately.

Net Contents

Six tubes, each 0.023 fluid ounces (0.67 milliliters)

Pet Gear Travel Lite Steel CratePet Gear Travel Lite Steel Crate3 MONTH Frontline Top Spot Orange:  For Dogs up to 22 lbs.3 MONTH Frontline Top Spot Orange: For Dogs up to 22 lbs.Reg price: $50.99
Sale price: $40.49
12 MONTH Frontline Top Spot Orange: For Dogs up to 22lbs.12 MONTH Frontline Top Spot Orange: For Dogs up to 22lbs.Reg price: $180.99
Sale price: $138.69
Naturvet Skin & Coat for Dogs (65 soft chew)Skin & Coat (65 chews)Reg price: $7.99
Sale price: $6.99
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Customer Reviews

DISCLAIMER: The results described on the testimonials on this site, are the individual experiences and personal opinions of those who have purchased and used the products. These testimonials are not intended to make any claims that the products can be used to diagnose, treat, mitigate, cure or prevent any disease or medical condition.
Click here to see all reviews
Works for my dog by karen v08/01/2013

Although some say this drug no longer works on their dogs, Frontline works well on my Yorkie. I'm resisting using the more powerful flea products on the market, and thankfully I don't have to.

Frontline Top Spot by Elliot1 from Marlton, New Jersey06/26/2012

I always recommend this site to my dog owner friends. You have the best prices.

dissapointed by onesadpuppy03/21/2012

Purchased this product for my Lhasa Apso weighing just under 20 pounds. After application on him, his skinned turned red and he can not stop scratching. To make matters worse....he still has fleas. I am very dissapointed with this product.

Safe and effective by Kim04/06/2012

We have been using Frontline Top Spot on our yorkie for the past three years. After being diagnosed with liver disease, this was recommended as the safest flea and tick control treatment for her. We have found several ticks but all seemed to have died immediately upon contact with her. Thank you Entirelypets for making flea and tick prevention affordable for our Roxy!

Frontline Top Spot by Maxine from Marlton, New Jersey06/04/2013

Recommended by vet at the cheapest prices

Product did not work by AJ08/15/2012

I have not had a problem in the past with this product, but the last shipment i received did not work at all. I had to purchase more Frontline from another vendor.

Excellent product by Nancy from South Carolina11/27/2012

I've had my 3 dogs on Frontline Top Spot for years and it has always worked very well for us. We live in a very flea-prone area (S.C.) and we rarely if ever notice a flea on any of our dogs if we keep them on Frontline Top Spot monthly. We definitely recommend it!

Great Prices by LM from Brookfield, CT.05/08/2012

I've been using Entirely Pets for about 6 yrs. and have been pleased with how quick I get my order and it's the same medication you would get from your veterinarian for a more affordable cost.

frontline by poodlgrl from Long Island, NY08/01/2012

I have been using this product for over 10 years now and entirely pets had a great deal on it and I feel its one of the safest flea remedy for my dogs

Solid Tick & Flea Protection by Bart11/27/2011

Our Annie has been using Frontline from day one. Tried another product once and regretted it. We'll be sticking with Frontline plus for the duration.

Might as well buy Frontline Plus instead..cheaper by Kim06/19/2014

Thanks to EntirelyPets for updated the listing to include the actual picture of the box…but the ingredients list is still not updated. This product is now the same exact formula as FrontlinePlus. I called the Merial company and they confirmed this. Why EntirelyPets is still charging more for the TopSpot doesn't make sense to me. Same exact formula! Might as well buy the Plus.

6 Month Frontline Top Spot Orange by Dee from Little Rock, AR03/10/2012

I have used Frontline for 5 years - vet recommended. I've found that Entirely Pets is the least expensive and the most reliable plus your order arrives very quickly. I highly recommend this company!

Happy With Frontline Top Spot by Sue from Plainville, CT12/17/2012

I've used Frontline products on my dogs for over ten years. They have never had fleas or ticks and have never had any type of adverse reaction to this product. It's easy to apply and leaves no messy residue. I'm very happy with your product and I'll certainly recommend it to my friends.

Problems by rebelthread11/29/2011

I was sent Frontline for Dogs, and had to return it, since I wanted Frontline for Cats. I bought what I needed elsewhere.

Frontline Top Spot by Chamois from NH10/14/2013

We have been using Frontline Top Spot on our dogs for the past 7 years. Never have we found a flea or tick on our dogs. In addition they have never had a adverse reaction to the product. The price I paid for this product from entirelypets was the best price I could find, so I'm very happy with my purchase.

wonderful by Karen03/18/2008

Been using this for my dogs for years. Love it, it works

Frontline Top Spot by Margie from West Des Moines, IA05/15/2013

Same product I always use for our dogs. Happy with the product but no so much the price.

Great Product by Kathy08/06/2014

Great product, great price. I prefer Frontline Top Spot because it is effective using the least amount of chemicals.


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