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Marin for Cats is a combination of silybin and vitamin E. It is available as a single strength.
Silybin is the most biologically active component of an extract known as silymarin. Silymarin/silypin has been shown to have beneficial effects on liver function. Vitamin E, a membrane-associated antioxidant, helps protect the liver against oxidant injury.
Marin for cats is specially formulated with silybin and vitamin E to provide comprehensive hepatic support.
Silybin/silymarin has many different mechanisms of action. In-vitro and in-vivo studies have shown that it protects agains oxidative stress; promotes protein synthesis within hepatocytes, a mechanism for liver cell regeneration; inhibits leukotriene production, which can be beneficial as production of leukotrienes is a component of the inflammatory response; stimulates biliary flow and production of hepatoprotecive bile salts (e.g. beta-muricholate and ursodexycholate) and increases levels of glutathione.
Vitamin E, a memberate-associated antioxidant, benefits liver function because oxidant damanage to hepatocytes can affect liver health. Vitamin E has been shown to reduce the oxidative damage to the hepatocyte mitochondrial membranes caused by hydrophobic bile salts (these bile salts build up in the liver when bile flow is impaired) Vitamin E use has been reported in cats for its antioxidant role that also help to support hepatic health.
My geriatric kitty has taken Marin and Denosyl for the last four years and both have made a significant and positive difference in her liver enzyme values. Marin is easy to administer, and as long as she gets it with a little bit of food, it does not cause stomach upset. This is a great product!