• S Adenosyl 425 (SAMe) for LARGE DOGS - 60 Tabs

    S Adenosyl 425 (SAMe) for LARGE DOGS - 60 Tabs

    Regular Price: $125.99Sale Price: $93.49
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    This item has been manufacturer discontinued. We recommend trying S Adenosyl 425 (SAMe) for LARGE DOGS - 30 Tabs

    S-Adenosyl-425 is an enteric-coated combination of SAMe, B-Complex Vitamins, Antioxidants and Amino Acids and is used to help manage liver disease. The uniquely tablet coating allows it to stand up formidably to stomach acid and effectively deliver the S-Adenosylmethionine (SAMe) to the small intestine for proper absorption. Veterinarians recommend this product when giving other medications that may adversely affect the liver, such as Phenobarbital, anti-convulsants, NSAIDs, and cortisone.

  • Helps Protect Liver Cells From Toxins
  • Reduces Damage Caused by Some Prescription Medications
  • Contains Antioxidants to Help Neutralize Oxygen Free Radicals

  • When liver function is compromised, the exact cause can often be difficult to determine. Support of the liver, regardless of the cause, is essential if function is to be improved. S-Adenosyl-100 has been shown to markedly increase glutathione levels in the liver of dogs and cats. It's activity goes far beyond just increasing glutathionine levels. It has also been shown to protect liver cells from cell death and may be useful in cell repair and healing.

    Usage Information

    Dogs 40 to 80 lbs 1 tablets daily
    Dogs over 80 lbs 2 tablets daily

    If giving more than one tablet, divide the dose between morning and evening.  S-Adenosyl-225 should be given on an empty stomach at least one hour before feeding. 



    Active Ingredient per Tablets:

    SAMe [S-Adenosyl-L-Methionine] 425 mg
    N-Acetyl L-Cysteine 40 mg
    Milk Thistle 80 mg
    L-Taurine 33 mg
    D-Alpha Tocopheryl Acetate 20 IU
    Zinc Ascorbate 20 mg
    Pyroxidine HCI 16 mg
    B-Complex Proprietary Blend 14 mg

    Inactive Ingredients: Coating Agents, Croscarmellose Sodium, Dicalcium Phosphate, Magnesium Stearate, Stearic Acid.

    Customer Reviews

    DISCLAIMER: The results described on the testimonials on this site, are the individual experiences and personal opinions of those who have purchased and used the products. These testimonials are not intended to make any claims that the products can be used to diagnose, treat, mitigate, cure or prevent any disease or medical condition.
    Click here to see all reviews
    works for my dog by drdirt04/09/2012

    my vet can't seem to get this in the larger dose and I got tired of having to give my dog Denver 2 pills a day.

    Fake by Jeff McLaughlin from Jeff McLaughlin Maine02/29/2012

    This product is a fake. Thats why its so cheap. I saved over 300 a month by switching to entirely pets. After a month after switching from the S-Adenosyl-425 I that I bought from my Vet. The S-Adenosyl-425 I got from Entirely pets made the dogs liver function go up. The Bottle is the same the Pill has the same shape But the color and look of the pill is different. THIS PRODUCT IS A FAKE.

    Amazing price by Nicky from New Zealand03/28/2012

    My 13 year old Border Collie has just been diagnosed with liver cancer. The vet recommended this product. However, we live in New Zealand & for a 6 month supply it would have cost me $1800 NZ to buy the product here. From this site it was $400 NZ even with international postage. The product arrived in less than a week & she happily takes them. This wont cure the cancer obviously but hopefully it will provide support for her liver so she continues with her energetic life for a lot longer.

    unknown by K9- officer from Rockland Maine02/17/2012

    My Vet told me not to buy these meds from a on line Company. The Pills that came were the same size and shape and the bottle was the same. The pills were a different color and texture. The price from entirely pets was 4 times cheaper than at the Vets. The dog is having blood work done the end of feb. we will see then if they are not as advertized. But if they are its a great deal and will highly recomend.

    SAMe for Dog by JC05/08/2009

    I feel this is an excellent product- my dog's liver functions were slightly high and when we checked again after 6 months they went up over 600. This product was recommended by my veterinarian and in 3 months,his liver function was down to just above normal around 300.

    Saved Money by Gene from South Florida12/22/2012

    My dog has to take this medication because of a deficiency in his liver. Entirely Pets saved about 50% on the cost of this product compared to what my dog's veterinarian was charging me, and it is the exact same product.

    A brand new dog! by Gray from NC06/30/2013

    I have a dog with seizures and this was recommended for him to help with his elevated liver enzymes caused by his medication. This not only helped with that, but the SAM-e really helped mellow him out and make him a happy dog!

    Adenosyl, the liver's best friend! by LT from Jackson, MS03/21/2012

    I have a 14 year old beautiful Walkerhound and his friend, a 3 year old black Chow. Both are taking Adenosyl as prescribed by our Vet. Their liver counts are monitored quarterly, both for different reasons. Neither would be with me today were it not for the Adenosyl and after a diligent Internet search I don't believe this product can be purchased for less than the everyday price at EntirelyPets.com. Thanks to them for helping me provide for my boys.

    MUCH CHEAPER by AJ from Memphis TN06/14/2013

    This is an everyday neccessity for our Bullitt. It was much cheaper on here for 2 month supply then to buy 30 day supply from our vet!!! We paid $90 for 30 at the vet. Never ever ever again will I do that! Great deal for exactly the same bottle.

    Good Price, super fast delivery and reliable by Miss Bobbie from Pollock Pines, CA04/09/2012

    I'd never bought from Entirely Pets, and boy was I happy! They had this supplement, and offered a great price which included free shipping. My dog needs this supplement for her simmering pancreatitis, so it's nice I know I can get it quickly. Thanks so much!

    Does the job. by browndog2 from Oregon10/30/2012

    This works to counter what another med does to my dog's liver. In 30 days her enzymes were back to the normal range.


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    Sogeval Products

    NASC Certified

    This product has met all of the stringent quality and safety standards set by the NASC.

    The NASC (National Animal Supplement Council) is a non-profit self regulatory group that set specific guidelines to which manufactures must strictly adhere.

    This seal is meant to minimize risk by providing an easy way of communicating to consumers that a product and its manufacturer meet particular standards of quality, customer safety and service.

    Those products that have the seal for NASC Quality and Safety standards have been strictly audited and were determined as meeting the following criteria:

    • Consistent manufacturing quality control
    • A system for evaluating complaints and adverse events
    • Clear and accurate labels compliant with codes and restrictions for all forms of labeling
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