DVM Pharmaceuticals has formulated an innovative, ready-to-use Tris buffering system in a non-irritating, alkaline, water-base formulation designed to prepare the ear canal for increased efficacy of antibiotic therapy in dogs and cats. T8 SOLUTION™ is an alkaline (pH 8.5), water based formulation designed to gently cleanse and rinse ear canals in preparation for more extensive therapies. A ready to use ear rinse and pretreatment solution for dogs and cats.
DVM Pharmaceuticals Commitment to Quality.
T8 Solution has been extensively field tested for both efficacy and irritation.
Manufactured under strict current Good Manufacturing Practices (cGMP) guidelines.
Rigorous stability testing, resulting in two year dating on every bottle.
Two-tiered manufacture testing
All raw materials tested for specification prior to release for manufacture.
Chemical and microbial testing on finished product.
Purified Water USP, Benzyl Alcohol, Nonoxynol 12, PPG-12/PEG-50 Lanolin, Tromethamine Base, Tromethamine HCl and Tetrasodium Edetate.
For rinse of ears to aid in removal of wax and debris before use of medicated therapies.
Directions for Use
Shake well before use. apply T8 SOLUTION™ liberally into ear canal. Gently massage base of ear to help break up and remove accumulated internal wax or crust. Use cotton or absorbent material to clean excess solution and debris from open area of ear. Repeat before introduction of medicated therapies or as directed by your veterinarian.
Store at room temperature.
For external use on animals only.
Keep out of reach of children.
Presentation: 4 fl oz (118 mL) (NDC 47203-600-04) and 12 fl oz (355 mL) (NDC 47203-600-12).
T8 Solution, containing Tetrasodium Edetate (EDTA), is an ideal adjunctive treatment for otitis externa, especially in cases of gram-negative infections such as Pseudomonas spp, Proteus spp, Escherichia Coli, and Klebsiella spp. Frequently, these cases become chronic and difficult to treat with topical formulations that are currently available because the bacteria associated with these infections develop multiple antibiotic resistance. Also, many antibiotics are inactivated or become less effective at the low pH level found in the exudate commonly associated with cases of gram-negative otitis externa. The low pH in acidifying ear cleansers may also lessen the activity of antibiotics if rinsed prior to application of the medication.
T8 Solution affects the cell membranes of bacteria by chelating minerals such as Calcium and Magnesium, causing the membranes to become more porous, thus allowing the antibiotic to break through the bacteria cellular wall and destroy it.
T8 Solution's alkaline pH (8.5)
Increases cell permeability, enhancing the penetration and effiency of antibiotics.
Improves the potency of antibiotics that are inactivated or become less effective due to the low pH found in exudate.
T8 Solution contains an anti-microbial/preservative agent to eliminate possible contamination of the solution after administration in the infective ear.
T8 Solution is non-irritating (tonicity of 222 mM, nearly isotonic).
T8 Solution contains mild surfactants for thorough cleansing of the ear canal.
T8 Solution is a ready-to-use ear rinse offering two-year stability, formulation consistency, uniformity and reliability.
T8 Solution is indicated for use prior to administration of other medications. T8 Solution should be gently squirted into the external ear canal 10 to 15 minutes prior to each application of an antibiotic solution. This combination treatment should run the full course recommended by the veterinarian.