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Add contents of one capsule (500 mg) into aquarium for each 20 gallons of water to be treated. Repeat in 24 hours. It is suggested that a partial water change be made between treatments. While duration of treatment depends on type and severity of infection, it is recommended that extended medication baths continue for a minimum of 5 days but no more than 10 days. Discontinue treatment if no improvement is noted within 5 days.