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Add contents of one capsule (150 mg) into aquarium for each 10 gallons of water. Repeat in 24 hours. It is suggested that a partial water change be made between treatments. While treatment duration depends on type and severity of infection, it is recommended that extended baths in the medication continue for a minimum of 5 days but no more than 10 days. Discontinue treatment if no improvement is noted within 5 days. To remove harmless yellow color, change 20% of water and use charcoal filter until clear.