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  6. Denamarin for Large Dogs Over 35 lbs (30 Tabs)

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Denamarin for Large Dogs Over 35 lbs (30 Tabs)

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Denamarin help protect liver cells from cell death and may help cell repair and regeneration. Denamarin also helps support your petís liver through the administration of silybin. Silybin is an active part of an extract from milk thistle, known as silymarin, and has been shown to support liver function by helping maintain a healthy oxidative balance.

When liver function is compromised, the exact cause can often be difficult to determine. Supporting the liver, regardless of the cause, is essential to keep it working properly. Administering SAMe (S-Adenosylmethionine), which is found in Denamarin, has been shown to markedly increase liver levels of glutathione, an important compound for liver health formed when SAMe is metabolized.

While best known for supporting the liver in dogs and cats, Denamarin also has a place in supporting brain health. Denamarin provides SAMe in a stabilized form to help with brain health and act as a neuroprotector. Denamarin also provides a bioavailable form of silybin which supports oxidative balance.

  • Increases levels of glutathione, an important compound for liver health
  • Has also been shown to help protect liver cells from cell death and may help cell reparation and regeneration
  • Supports petís liver with silybin, which maintains a healthy oxidative balance
  • Provides SAMe in a stabilized form to help with brain health and act as a neuroprotector
  • Easy to administer, chewable tablets for large dogs
  • Ingredients

    S-Adenosylmethionine (425 mg) and Silybin A+B (35 mg)

    Useful Information

    Weight Daily Feeding
    35-65 lbs 1 tablet
    66-120 lbs 2 tablets
    Over 120 lbs 3 tablets

    Customer Reviews

    Review Summary
    205 Reviews
    83% (170)
    12% (24)
    3% (6)
    0% (0)
    2% (5)
    95% Recommend this product (195 of 205 responses)
    By GBG
    Yucaipa, Ca
    Denamarin Meds
    September 22, 2020
    It appears that it is helping my Gordon Setter Liver function. Good product.
    Merchant Response:We feel the same way about your pros and cons. Wish it wasn't so expensive, but it's a difficult substance to produce. It oxidizes rapidly once exposed to oxygen. Great care is taken during manufacturing including doubling the active amount as well as entracoting and blister packing. Take care GBG!
    ProsReasonably priced for this med/
    ConsStill a bit pricy
    By Linda
    Great for dogs with liver issues
    September 15, 2020
    My vet swears by this product and it has kept my dogís liver issues in check for six years.
    ProsIt works
    By Neal T.
    Purchase of Denamarin
    April 27, 2020
    Great price and quick delivery. What more can you ask for.
    Prossee above
    Consno cons
    By Summerbuff
    Wilmington, NC
    Works great!
    April 24, 2020
    My vet recommended this product to reduce my dogís ALT and it has definitely helped.
    ProsEffective Easy to administer No side effects
    ConsExpensive but worth it and Entirely Pets has the best price
    By Ilse
    Wstern, Maine
    Vet recommended
    April 23, 2020
    My vet recommended Denamarin for our dog as her liver enzymes were elevated. After just one month, her levels had dropped to almost normal levels. I will keep her on this for sure!
    By Kenton B.
    Dog Liver Function Decline
    April 10, 2020
    My Hannah's liver (she is 12) started declining in function last year (Please do a complete blood panel on your pups every year!). My Vet recommended Denamarin as the first course of treatment. It really helped improve her enzyme numbers. Now she is also on an additional med and we have stabilized or really slowed the decline of her liver function. She is active, happy and eating well.
    An expensive product but liver blood screens showed it to be very effective in my case.
    Merchant Response:Beautiful Denamarin testimonial Kenton. Be well
    ProsEffective in my dog's case.
    By Regina M.
    Helps my dogs liver
    February 11, 2020
    Blood work came back better after being on this.
    ProsDog likes it.
    By Paul B.
    Quick Delivery, Good Price
    December 31, 2019
    Exactly what the vet wanted for our dog. Delivered quickly at a good price.
    By Cynthia
    Omaha, NE
    Great Product at a Great Price
    December 29, 2019
    Recommended by our Vet for our dachshund. She has been on this for several years and helps her liver condition. Great price!
    By Brenda W.
    Denamarin for Cats and Small Dogs up to 12 lbs (30 Tabs) Was: $36.99 Sale Price: $27.99
    December 28, 2019
    Helped my Stella's liver numbers go down,
    By MB
    Great Product!
    August 17, 2019
    My dog has been taking these for a few years now. Great product!
    By Chase
    Excellent service
    June 30, 2019
    Quick very easy transactions will keep purchasing from entirely pets.thank you
    ProsAll good
    By Chris
    Quick an easy
    June 27, 2019
    Easy to order and at a great price. Product arrived quickly. Very satisfied.
    By Sharon
    Cool, CA
    Is improving my dogs liver enzyme levels
    June 24, 2019
    Have been giving this product for a few months now, and seems to be helping improve many of his liver enzyme levels.
    ProsEasy to give - he is a 60lb border collie, and he gobbles them up like treats.
    By Jeannette
    Anahuac, Texas
    Denamarin chewable
    June 23, 2019
    I really like how my dog will readily take this medication.
    ProsEasy to give to my dog
    By Hope
    Brooklyn NY
    June 21, 2019
    I give this product everyday to my dog Brooklyn. Vet recomended this for her liver. It keeps her healthy.
    ProsHelps with your dogs liver function.
    By Darryl G.
    Great product for High liver Enzymes ☆
    June 14, 2019
    Been using this product for my 12 year old Schnoodle with liver issues and it has done an Excellent job; Price is Very reasonable on Entirely Pets!
    ProsGood Price & Product
    ConsNone as of yet!
    By Melissa
    Helpful tip with Cat
    June 10, 2019
    Just wanted to give a tip I found when giving this to cats since it should not be crushed: get it wet. At first my cat took it fine, then she caught on and it became a case if cheeked meds. She'd run off and drop it elsewhere. I thought to run in under the faucet for a second just prior to giving it. Seems to work! She doesn't love it but it goes down with ease!
    By Donna
    Scranton, Pa.
    liver problems
    June 4, 2019
    This product helps my dog live a better life.
    By Claudia
    Iowa City, IA
    Works great
    June 3, 2019
    Great price for a great product.
    By Marcia
    Great buy
    June 1, 2019
    Received mdse in good order and promptly. Good price.
    By Barbara
    Milwaukee Wisconsin
    Great pet website!
    May 30, 2019
    I was able to find the important medication my dog needed at a great price! Website is easy to use and products arrived on schedule. I will definitely order again!
    By jenmckeel72
    West Jordan Utah
    Best stuff around for liver issues!
    April 14, 2019
    Highly recommend for any dog that has liver issues. Keeping my dog on Denamarin has helped keep her liver healthy.
    By Lufer
    Maryville, TN
    March 28, 2019
    My terrier mixed breed dog refuses to ingest the product no matter how it is prepared (e.g., as a "chewable" tablet or crushed and mixed with virtually anything). Wish I had purchased pills vs tablet.
    By Bonn
    Review for Denamarin 225 mg for Dogs (75 Tabs)
    December 10, 2018
    2 vets & a vet internist have recommended Denamarin for my dog with kidney disease. We had difficulty with the caplets bc they were too large for my 6 lb. dog. When cut in 1/2, both halves must be given at once--company says they cannot be saved, and still be effective, for later. The chewables solved the problem, as portions of them can be saved. Neither of our dogs will eat them, but the co. said dosing with no more than 1 tsp. of wet food or similar is okay. This is working out well. d I do wish they were scored into 1/4s.
    By Rappo
    So Cal
    Really Helps
    September 18, 2018
    Our little Kiwi is doing so much better now that we've gotten him on his meds! Thanks Entirely Pets
    ProsKeeps my Older Pup healthy
    ConsIt can be expensive
    By Janemarks
    Normal Liver Test!
    August 29, 2018
    I was giving my dog Denosyl as her blood test showed low liver function. I started giving Denamarin and at her 6 month blood test she showed for the first time in 2 years a normal liver function.
    Prosincludes milk thistle in each dose
    Conshaven't seen any
    By Goldice
    Anchorage, Alaska
    Wish I didn't have to...
    May 17, 2018
    I'm hoping that the choice I signed up for (repeat purchase automatically every month) is complete. Getting it from Entirely Pets is considerably less costly than getting it from my vet.
    By Pam
    Great value
    October 6, 2017
    With our dog having to take Denamarin for an extended time, Veterinarian recommended to purchase online. Economically, the 75 count is perfect for our current needs.
    By Cher
    New England
    Saved my Dog's Life
    October 1, 2017
    My lovely Belgian Tervuren Mix became like a couch potato and just was not herself. The vet did bloodwork and found her liver count was over 1,000!! Liver failure. She put her on Denamarin and now it stays at just over 100. It keeps her healthy and alive!! I cannot say enough about this product. It also shows that getting bloodwork done at least once a year is very well worth it.

    Questions and Answers

    1 Question & 0 Answers
    from Cranberry Twp, PA asked:
    August 26, 2015
    What is the size of the 425 mg tablet?

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