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Frontline Spray (500 mL)

Item: FSPRAY10011
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Frontline Spray for Dogs & Cats can be applied directly for both immediate and long-lasting control of fleas and ticks for up to 30 days. This effective spray contains fipronil to kill existing flea and tick infestations. It also kills fleas before they lay eggs, effectively preventing reinfestation. Safe for puppies and kittens 2 days of age or older, Frontline Spray helps reduce flea and tick infestations in multi-pet households, and is great for the initial treatment of flea allergy dermatitis. The spray bottle is easy to use, provides fast and even application and can be reapplied regularly.


  • Kills Fleas
  • Kills newly emerged adult fleas before they lay eggs
  • Stops existing infestations and prevents establishment of new infestations
  • Kills fleas which may cause flea allergy dermatitis


  • Rapidly eliminates chewing lice infestations


  • Aids in control of sarcaptic mange infestations in dogs
  • Kills all life stages of ticks (larva, nymph and adult), including brown dog ticks (Rhipicepalus sanguineus), American dog ticks (Dermacentor variabilis), lone star ticks (Amblyomma americanum) and deer ticks (Ixodes scapularis).
  • Kills ticks that may transmit Lyme disease, Rocky montain spotted fever, ehrlichiosis, babesiosis, anaplasmosis, haemobartonellosis and other tick-borne diseases

Frontline Spray is great for controlling emergency flea infestations as well as for regular use and along with with other monthly flea and tick medications like Frontline Top Spot, Frontline Plus, or Advantage.

Frontline Sprays do not contain the potentially toxic insecticides found in most pet store sprays.


Fipronil 0.29%
TOTAL 100.00%

Useful Information

It is a violation of Federal law to use this product in a manner inconsistent with its labeling. TO PREVENT HARM TO YOU AND YOUR PET, READ ENTIRE LABEL AND ATTACHED DIRECTIONS BEFORE EACH USE. Follow all directions and precautionary statements carefully. Use only on dogs and cats. Do not use on rabbits. Do not use on any other animals.

To kill fleas and all stages of brown dog ticks, American dog ticks, lone star ticks, deer ticks (which may transmit Lyme disease) and chewing lice, apply FRONTLINE® Spray to dogs, cats, puppies or kittens as follows:

To Open: Push the button on top of the trigger and turn the nozzle to the spray position.

To Close: Push the button on top of the spray and turn the nozzle to the X position.

  • Wear household latex gloves.
  • Hold the bottle in upright position. Ruffle the animal's coat with one hand while applying spray mist to the animal's back, sides, abdomen, legs, shoulders, and neck.
  • For head and eye area, spray FRONTLINE on a gloved hand and rub gently into animal's hair.

Do not get this product in your pet's eyes or mouth. Apply spray mist until animal's hair is damp to thoroughly wet. Approximately 1 to 2 pumps per pound of the animal's body weight will be required. Pets with long or dense coats will require the higher rate.

As with any flea control product, wash hands and exposed skin thoroughly with soap and water after use.

To prevent flea build-up pr reinfestation, use FRONTLINE Spray prior to the onset of flea season and monthly thereafter. Ticks do not need to receive spray directly upon their body for complete control. Multiple monthly treatments are recommended for the elimination of mites. Do not reapply to spray for 30 days.

FRONTLINE Spray remains effective even after bathing, water immersion, or exposure to sunlight.


HAZARDS TO HUMANS. CAUTION. Harmful if swallowed or absorbed through the skin. May cause severe eye irritation. Avoid breathing spray. Avoid contact with skin, eyes or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, or using tobacco. Persons applying this product must wear household latex gloves.


For external use only. May cause severe eye irritation. Take care not to spray in the animal’s eyes or facial area. Do not use on kittens and puppies under eight weeks. Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist or become more severe, consult a veterinarian immediately. Certain medications can interact with pesticides. Consult a veterinarian before using this product on medicated, debilitated, aged, pregnant or nursing animals.

WARRANTY: To the extent consistent with applicable law, the Seller makes no warranty, expressed or implied, concerning the use of this product other than indicated on the label. Buyer assumes all risk of use and handling of this material when such use and handling are contrary to label instructions.

FIRST AID Have the product container or label with you when calling a poison control center or doctor, or going for treatment.

IF IN EYES: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice.

IF ON SKIN OR CLOTHING: Take off contaminated clothing. Rinse skin immediately with plenty of water for 15-20 minutes. Call a poison control center or doctor for treatment advice.

IF SWALLOWED: Call a poison center or doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything by mouth to an unconscious person.

Customer Reviews

Review Summary
49 Reviews
76% (37)
8% (4)
2% (1)
4% (2)
10% (5)
78% Recommend this product (38 of 49 responses)
By Mary
very good product
July 4, 2017
I got this for my sister very large dogs to apply in between treatments and is working real well.
By Mh
Great product
June 20, 2017
Been using this for years. A must for having multiple dogs, saves money. Never had any fleas in over 20 years.
By Rosie
Little Rock, AR
Starts working immediately
May 3, 2017
I've used it before on my cats and it worked great so though I would try it on the dogs. As expected, works wonderfully. I spray it on their paws, webs, fur etc. and this stuff does the trick. If I do find a tick it's usually in the dehydration state and fading quick.
By Hope
Atlanta, GA
Very Good Product
October 29, 2016
This Spray works well and is very strong. I would recommend it to help and aid in getting rid of fleas. This is a very good price also. Thank you.
By skyhawk
best product on market
July 24, 2016
works better and quicker than topicals that you have to cut open to apply
By Tina
Speedwell, Tn.
Great Product!
July 12, 2016
I have raised Chihuahuas for years and use this product to keep the fleas off them. I have long and short coat and it works great on both. Love it!
By cadfarm
Excellent Results
March 30, 2016
I have been using this product for years. Very effective for fleas and ticks. It is cost effective and I like having the control over the amount of product I apply. I use it on my dogs and cats.
By bibitte3171
Quebec, Canada
Super produit
March 25, 2016
Excellent produit! Traitement facile et rapide en une seul fois. Fini les puces. Le produit livre ce qu'il proclame. Moins cher qu'un traitement chez le veterinaire et plus efficace.
By Mandee
Jefferson County, TN
Waste of Money!
June 16, 2015
My parents always used Frontline Spray on our Pugs. It worked amazing before they done away with it! Since they brought it back, it just hasnt been the same. I gave my animals a bath before putting it on them. They ended up with more fleas after I sprayed them with it than they had before. This is the second bottle I purchased and it will be the LAST!
Frontline does the best for fleas and ticks.
April 13, 2015
I live in the country with lots of fleas and ticks. I have 10 cats and 3 dogs. Frontline is the most economical for me and it works real well.
By oeg
battleground WA
February 19, 2015
works fantastic on my cats dogs and my show chickens
By el
July 6, 2014
I ordered the Frontline for my son who has 15 dogs. Worked well. He also has 3 cats in the house who had brought fleas in. He sprayed them and I ordered outside spray for him and inside for both of us, WORKED VERY WELL! I also ordered siphotrol for outside and inside. I had my dog on a med which didn't work and I got fleas inside. The inside spray killed all the fleas inside!
By Moo
Doesn't quite work...
June 8, 2014
Disappointed. The fleas remain on the dogs and cats after i spray them. Not sure if the fleas developed immunity against the chemicals or if the ingredients are different. Ah well. Time to go the nontoxic hippy route.
By Dobiedog
Suffolk, England
Essential Standby
June 5, 2014
The guaranteed way to remove fleas from your dogs. It really works, unlike so many other flea preparations. It is an essential standby during the summer months when fleas are active. It also has the added benefit of keeping them off the dogs for several weeks afterwards.
By Robin
Does not ship well
November 21, 2013
I do not recommend buying this item through the mail as mine arrived with at least 1/3 of the product missing. It had leaked. Other than that it seems to work. I have not found any fleas or ticks on my dogs.
By may j.
frontline spray
November 17, 2013
i do not have a heavy flea problem here.found a few on the cats.dogs use sentinel and parastar.spray worked for eight days and fleas re-appeared!
By Angie
Not enough product
October 29, 2013
Would not buy this again. Worked for only one night. I bout advantic, and now see a 90% improvement in just a few days.
By Marie
Excellent purchase
October 2, 2013
Work in veterinary hospital. Price is great & product works fantastic. Have used it for years & will continue using it & recommending it to everyone for flea & tick treatment.
By sjpfl
Best Price on Net!
August 12, 2013
Have used this product for years. Best part is service from Entirely Pets - always prompt.
By LilwithCats
Eugene, Oregon
Great In Betweens
June 11, 2013
The Frontline Spray is great to spray on my cats in between their regular flea treatments and especially if you have multiple pets!
By Marsha
Fayetteville, AR
A consistent quality product
May 12, 2013
I have used Frontline spray for several years. It seems to be the best for immediate protection from fleas and ticks. My dogs trail ride with me and need something that really works when they've been exposed.
By FleaBit
April 30, 2013
I started using the Fontline Spray after reading the reviews.
My little Min Pin has fleas and I gave him a flea bath and the next day used the Frontline as directed. The next day, Fleas. I used it again as directed even though we just did it a day before. The next day and the days after, Fleas.
I used 3 to 5 times the amount suggested and the Fleas dont seem at all bothered by it. I am going back to the OIL.
By Sue
Belleville, MI
Great for Multiple Pets
March 16, 2013
This is an economical way to treat multiple pets and it goes a long way!
By GiniFM
Houston, TX
March 13, 2013
I hesitated between the pray and spot on versions. Read reviews that said that both protected well but the spray was cheaper. Now with the Revolution and Frontline, the dogs are fully protected !
By holly
Such a great product!
March 10, 2013
Frontline spray has been around for some years now and there are many new products out there, but I have found it to be one of the most effective and dependable products for flea control that I have ever used. Thank you for selling this great product.
By randymann
November 7, 2012
Frontline flea spray works...others don't. Great product, good price, fast shipping.
By meowmom
dallas, texas
frontline fans
May 30, 2012
we have used frontline spray for years. i have tried other products but keep coming back to frontline. i've stopped buying the others and stick to frontline.
By wankaye
Birmingham, Al 35208
Good Stuff
May 29, 2012
I was so happy when they started back selling this Frontline spray, I've used it for years on my pets and it does work but you also have to use the pills that kill fleas also, the monthly pill to keep them under control
By Judy
Best flea medicine ever!
May 29, 2012
This year I thought I just couldn't afford the Frontline flea spray for my 3 cats, so I opted instead for the Pet Armor. Administered 1st dose to each cat. No noticeable difference. Treated them again with a different product. Still fleas. In cleaning out my cabinets, I found a small (250 ml) bottle of Frontline flea spray and it was just barely enough to treat all 3 cats. You should have seen the fleas "fleeing" the ship! I will not try any other product. I wish I could find this locally at a feed store or pet supply store, but I am SOOO happy it is at least available online. has an excellent price, so I will continue to buy here.

PLEASE don't stop carrying this product. It is also the only product safe for use on kittens 2 days of age or older. Plus, it's not absorbed into the skin like the squeeze on products.
By ProperBostonian
The Must-Have Product
May 29, 2012
I use Frontline spray on my horses legs, bellies and under their chins every 2 weeks as recommended by my veterinarian. Living in New England with an epidemic in tick-borne illness such as Lyme, I have learned the best defense is a good offense in the war against ticks. I spray on before we go out on the trails and noticed a huge decrease in finding ticks on my horses. This is a great product for us!

Questions and Answers

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Frontline Spray (250 mL)Frontline Spray (250 mL)Reg price: $42.99
Sale price: $32.99
3-PACK Frontline Spray (750 mL)3-PACK Frontline Spray (750 mL)Reg price: $127.99
Sale price: $97.99
3-PACK Frontline Spray (1500 mL)3-PACK Frontline Spray (1500 mL)Reg price: $228.99
Sale price: $175.99
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