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4 MONTH Advantage II Flea Control Small Cat (for Cats 5-9 lbs.)

Item Number: 5461669
Regular Price: $52.99Sale Price: $44.99
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Advantage II Flea Control Medium Cats 5-9 lbs

Keep your cat and your home safe from fleas with Advantage II Medium Cats 5-9 pounds. Formulated for cats eight weeks and older and weighing 5 - 9 pounds, Advantage II kills fleas within hours of application and protects against future flea infestations.

The Importance of Flea Protection

Protecting your cat from fleas is essential for health and well-being. Flea bites not only cause discomfort for your cat, but also can cause irritation that can lead to skin infections. In some cases, flea bites can lead to allergic skin reactions, or even result in the transmission of other disease-causing organisms, such as tapeworms.

life cycle of the commom flea
Flea life cycle.
View larger.

Kills Fleas Within Hours of Application

Millions of pet owners have found success against fleas with Advantage Topical Solution. Its successor, Advantage II, kills even more flea life stages. Advantage II kills fleas through contact, so they don't even have to bite to be destroyed. This helps reduce the risk of secondary problems, such as flea-allergy dermatitis.

The active ingredient in Advantage II, imidacloprid, acts on the nervous system of the flea to cause paralysis and subsequent death. Advantage II destroys the fleas living on your cat within 12 hours of application, providing quick relief for your pet. Reinfesting fleas (newly hatched fleas jumping back on your cat) are killed within two hours of application, so if your pet picks up fleas from another animal or infested environment, those fleas will be killed as well.

K9 Advantix II Lifestyle shot
Advantage II Flea Control
Medium Cats 5-9 lbs
  • Kills fleas within hours of application
  • Breaks flea life cycle, protecting against future flea infestations
  • Waterproof formula won't wash off
  • Easy to apply
  • Includes twelve convenient one-month doses
  • For cats eight weeks and older and weighing 5-9 pounds
  • Per Dose: $10.00
Advantage II Flea Control for Kiteens - Product Features
Flea Cycle
The adult fleas you see are only a small percentage of the infestation.View larger.
Protects Against Further Flea Infestations

If you are already dealing with a flea infestation, you may only be aware of the adult fleas, which comprise a mere 5 percent of the full infestation. The flea eggs, larvae, and pupae make up the other 95 percent of the infestation and can be virtually invisible to the eye. The insect growth regulator contained in Advantage II effectively breaks the flea life cycle at multiple stages to treat existing infestations and prevent future infestations. Each dose of Advantage II provides protection for an entire month.

Waterproof Formula

Advantage II is waterproof, so there's no need to reapply after your cat has a bath or goes out in the rain. Studies show that cats are still protected against fleas after exposure to water, though for best results, cats treated with Advantage II should be bathed with a non-detergent shampoo.

EPA Registered Logo

This Advantage II product is EPA approved and registered, so it's guaranteed to be the exact same product sold by your Veterinarian. Click here for more information on EPA-approved pet products.

Package Contents

Two boxes of six include 0.4-millimeter tubes of Advantage II for Small Cats.

Advantage II for Cats Is Available In:
Small Kitten
(under 5 pounds)
Medium Cat
(5 - 9 pounds)
Large Cat
(over 9 pounds)
4 month
4 month
6 month
12 month
4 month
6 month
12 month


Usage Info

How to Apply

Applying Advantage II to your cat is a fast and easy process. First, remove the applicator tube from its packaging and use scissors to peel down the foil. Next, hold the applicator tube in an upright position and pull the cap off the tube. Use the upturned cap to break the protective seal, and you're ready for application.

How to apply

Part your cat's hair on the back of the neck at the base of the skull until the skin is visible, then place the tip of the tube on the skin and gently squeeze out the entire solution. Placing the treatment here minimizes the cat's ability to lick the product, which is bitter tasting and may cause salivation for a short time if licked after it is applied. Do not get this product in your cat's eyes or mouth. Dispose of the container and do not reuse or refill. Do not empty unused product in any indoor or outdoor drain.

For optimal control and prevention of parasites, use Advantage II every month. Do not use this product on any animals other than cats.

Length of Effectiveness

Under normal conditions, Advantage II is effective for one month. However, in cases of severe flea infestation, retreatment may be necessary earlier than four weeks. Do not retreat more often than once every 14 days. After flea control is attained, return to a monthly retreatment schedule.


See back panel for first aid. For instructions on storage and disposal, see supplemental labeling inside package.

Keep out of reach of children.



How long does it take to kill all fleas after the first application on an animal that has fleas?

24 hours to zero fleas counted.

Does it kill ticks as well as fleas?

No, there is no tick activity at all. This product is highly specific for fleas.

Activity against parasites other than fleas and ticks?

Fleas only.

How long does a single application last?

One month.

How soon after bathing can it be applied?

As soon as the pet is dry.

Does it wash off?

Yes, this product washes off completely with a degreasing shampoo. It can withstand one bath between applications and swimming once a week between applications, but no more.

Flea-killing active ingredient?


How young can the cat be for application?

Eight weeks.

Approved for use in pregnant or nursing mother cats?

Not in this country, but approved in other countries (US EPA does not recognize testing done for other countries and testing in pregnancy/lactation has not been done in the US).

Does the pet need a veterinarian office call in the last year to get the product?

No, this is an insecticide, not a drug. However, the manufacturer sells its product for resale only through veterinarians, so proper usage, etc. can be explained.

Is the product safe for use on sick, elderly, or debilitated patients?

Product should be safe for such use provided the patient is receiving veterinary care. Otherwise, if the pet is inactive or hospitalized in a cage, the product may not spread around the body as rapidly as usual.




Imidacloprid is an ectoparasiticide, an antiparasitic agent that targets parasites living primarily on the surface of a host. Chemically classified as a chloronicotinyl nitroguanidine, imidacloprid inhibits neurotransmitter transmission in insects, resulting in paralysis and death.


Imidacloprid exhibits both adulticide and larvicidal flea efficacy; it not only kills adult fleas and larvae on your pet, but it also kills larval stages in your pet's immediate surroundings.

Main Purpose

To kill fleas at all stages of their life cycles and stop them from being able to move or feed.


Pyriproxyfen, the added compound in Advantage II, is a pyridine-based pesticide. A juvenile hormone analog, it interferes with the hormone signaling of growing insects, so that insects in immature stages are unable to mature. Additionally, a female insect that touches the toxin will produce eggs that will not hatch.


Pyriproxyfen provides an added layer of protection for pets and their surroundings. It interrupts the flea life cycle at multiple stages, halting the growth and development of insect eggs and larvae and preventing reinfestation.

Main Purpose

To prevent flea eggs from hatching and larvae from growing.

Active Ingredients % by Weight
Imidacloprid 9.10%
Pyriproxyfen 0.46%
Other Ingredients 90.44%
Total 100%

Net Contents

Four tubes, each 0.014 fluid ounces (0.4 milliliters)

12 MONTH Advantage II Flea Control Large Cat (for Cats over 9 lbs.)Advantage II L Cat 12MReg price: $141.99
Sale price: $121.99
4 MONTH Advantage II Flea Control Kitten (for Cats under 5 lbs.)Advantage II KittensReg price: $52.99
Sale price: $36.99
6 MONTH Advantage II Flea Control Small Cat (for Cats 5-9 lbs.)Advantage II S Cat 6MoReg price: $71.99
Sale price: $61.99
12 MONTH Advantage II Flea Control Small Cat (for Cats 5-9 lbs.)Advantage II S Cat 12MReg price: $141.99
Sale price: $120.99
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Customer Reviews

Click here to see all reviews
4.68 rating based on 453 reviews
Works Like a Charm by Kitty06/17/2013

The product does what it claims to do: kill fleas instantly.

Good by Rg04/23/2012

It worked quickly both of my cats stopped itching immediatly

Works, and affordable by Littlebit55 from Maryland10/23/2012

I was hestitant to purchase a topical, but the fleas this year were unbelievable, I had huge outbreak. I had a couple of cats , long hair, where I coudn't really get them under control so I used this. It works, it's affordable. Plan on having this at the beginning of flea season next year to prevent the problem instead of having to cure the problem.

didn't work well at all by Wing08/08/2012

We have used Advantage on our cats for years now, but this particular batch is very substandard! It didn't smell much and the cats did not mind having it on at all. This is not usual. They usually hate it for a few days. But most important, it didn't kill all the fleas. The cats still have some fleas on them but our vet said not to put more on the cats within the month.

Not a flea in sight! by ren from Waterford Ct.07/01/2013

Taking in a rescue cat was a concern regarding fleas. We applied Advantage II the day before we brought her home. She gets it once a month. Easy to apply , no flea collars to get hung up on. Love it.

the answer for me by wildflower from edinburg, va12/05/2012

Have had trouble with fleas on the cats all summer. Switched to advantage and the scratching is over thanks

Easy to use..controls all areas. by Luv4pets from Rochester11/07/2013

Years ago I took in a kitten and named her "Peanut" because she was so tiny. Well, she didn't grow very big and I kept her inside with the rest of the cats, who adopted her nicely. The Advantage II Flea Control Small Cats works the best for her as I do have one cat that goes out and a dog. Knowing they can bring fleas in, as well as I could, I treat her with this product faithfully.

Excellent Product by Sue07/18/2012

Not only is the product excellent the price was better than other sites I searched and it was delivered promptly.

Only way to go! by Gabby08/27/2013

This product is very good quality. It is very effective and acts quickly. The price is a fraction of what you would pay at a vet. I have 4 cats and a dog so the savings to me are definitely worth it for a product that works.

by from 07/09/2012

Another Great Product by Bernie from Pacifica, California12/06/2011

Advantage II Flea Control for small cats works wonders. Just like the Advantage II Flea Control for 9lbs and over that I use for my other cat the fleas seem to disappear overnight. I was using another product from another company and my cat would have scabs after using it but with Advantage II from Entirely Pets.com my cats coat is back to it's beautiful, soft self again. Thank you for a great product.

Advantage for Cats/Order Placed for my Mother by Sherri McGee from Indianapolis, IN10/28/2011

It was NOT clearly marked for "Fleas, Tics, etc." and that is what she truly needed, so now both of us are not going to order online again, as you can not be sure your getting what you ordered.

Good quality flea med by Sparky from Terre Haute, IN11/26/2012

Advantage II is good stuff - it used to get a bad rap compared with Frontline, but what I've noticed is that fleas appear to develop immunity over time: I'd used Frontline for 2-3 yrs, then it stopped working. I switched to Advantage & the fleas just fell off the cats. It's about time to switch back, but my point is, Advantage is just as good & they've also improved the product in the last few years. I've not found better prices than Entirely Pets, either.

Advantage 11 by the cats from Westport, MA06/10/2013

love this product. Used to use frontline, but this one has exceeded my expectations. I have 6 cats, so we need to be flea & tick free!!

Advantage II For Small Cats by Michannemag from Bakersfield, CA02/07/2013

Excellent product and the fleas disappeared immediately. Love this stuff for my kitten. Venus is pictured. We found her in a flower bed when she was 2 weeks old. I took her inside and started bottle feeding her 4 to 5 times a day. She has grown wonderfully and we love her so much!

Great buy! by kevman08/01/2012

I tried a generic brand of frontline. Didn't work. My cats had fleas crawling all over them & I purchased Advantage & fleas were gone in 24 hrs.! Product didn't make the cats nuts like other meds. I would choose this product over frontline.

by Sparrow07/05/2012

It works when there's not a *bad* infestation. For normal maintenance, it seems to do the trick.

flea meds by ChrissieBug from So. Florida06/10/2013

I have four cats and now a puppy.....entirely pets help keep our pets happy and healthly at a reasonable price with quick shipping

Can't Do Without by Teapot from Mobile, AL06/26/2012

Have 5 cats and each month on the 24th they all get treated. Not that they are happy about it but I am cause there are no fleas or ticks on them or in my house.

Seems to work by Joe from NC01/16/2015

Since the product was applied there have been no sign of fleas.

The BEST FUR Sure! by Frankie from Pittsburgh, PA02/03/2014

After 3 treatments of Frontline Plus Failure...the Advantage gave immediate relief to my Pets and to my Well-being too. Will never use anything else!

good product by catlady24/701/16/2014

My cat weighs 7 lbs (right in the middle for this product 5-9 lbs). It did help but the next dose that I used was for larger cats (over 9 lbs). It gave me more of the liquid and did not harm my cat. Killed fleas as described. Did not have a strong odor like Frontline Plus. Flea infestation was very bad in 2013. I have indoor cats and they still got fleas. I plan on getting a jump start on battling fleas when spring arrives.

Effective by Pam01/01/2013

This product works quickly to kill all stages of fleas. Others I used did not kill the larvae or eggs and my cats developed extreme allergies to flea bites until this finally got rid of them. My cats are strictly indoor cats so it was important to me to make sure the fleas did not get serious and infest the house. Not sure how the cats even got fleas in the first place.

by from 05/30/2012

One of the foil packages of the product was smashed in transit.

got by an from immediateI


Great service by Nancy from Portland, TN11/14/2011

Rid my cats of fleas and the shipping was fast. Thanks

Sorry by MsScarlett from Oceanside,CA09/12/2014

sorry to say, none of the brands work this year. the fleas just laugh and continue to plague us.

horray! advantage 2 by Sandie-ra from Roseville,MI11/03/2013

Still no fleas it has been a month,still in the clear,thank you sooooo much! Good product for the price.Do not forget to use the coupon codes!

by from 09/03/2013

by from 10/13/2011

I was very dissatisfied with this product and even called to see if I could return it.

used by Advantage from inI


I love this product by Laura Adair from Bobcaygeon, Ontario07/31/2012

I found Entirely Pets web site last year. I am so glad they ship to Ontario, a lot of the sites I went on didn't. I ordered the Advanage II for my cat and my dog. It works really fast. Enirely Pets shipping is pretty fast. I usually get my package with in 1 1/2 weeks. Their prices are affordable and it's the same product you would get at the vets. I have told a lot of people about Entirely Pets.

Awesome product! by DaisyGirl from Atlanta, GA04/15/2012

This product has helped my babygirl Daisy win the fight over flea allergies. She normally has a hard time with sores and bumps from flea bites. We live in GA so we have fleas year round! Thanks for selling this great product!

by Sun Girl11/06/2012

Love the product. Easy to apply & it really works!

Keeps the fleas away by Cat lover from North Carolina06/17/2013

Good product that is easy to apply and effective

Good Flea Control by ccc3 from CT12/16/2012

Fast delivery! Easy to use and apply, vet recommended product

arrived on time by keylime07/03/2012

Happy with my order, was shipped right away, no long wait time. Very pleased!!!

indispensable by CCL11/29/2011

Although only one of my cats likes outside, they all get fleas. This product is a must have-easy to use, inexpensive, and very effective

The only one by CH from NH08/21/2013

This product advantage II along with using the capstar works the best to rid your cat of fleas

Advantage II Flea Control by dlmi from Maine04/08/2012

I am back buying more Advantage II for a flea free summer. Cat's are treated and I'm confident we will not have a problem this year. This stuff works best for us.

Advantage II by lambchp12/06/2012

Seems to work well. Recommended by my vet as the best anti-flea treatment.

Very good purchase by Scoobydoo1 from ONTARIO CANADA06/23/2014


Flea medication by angelplum53 from Pittsburgh, PA05/22/2013

This product works great on my 15 year old outdoor / indoor cat. I use it every year. Price is right too compared to what vet sells it for.

advantage ll flea almost killed my cat by earth mother from miami florida03/29/2014

when I gave my cat his second dose of advantage ll flea control for small cats the next day he was comatose and it took a bath with detergent and two weeks before he returned to normal . Emotionally exhausting as well as a hefty fee from vet for blood work to determine what cause was. My vet told me he no longer carries advantag ll for cats as this isn't the first cat to react to this medication. vet's advice, use revolution my advice, don't use advantage if you love your cat.

Works fast and effectively!! by Trish from Venice Fla03/18/2013

Kills fleas fast!! Best product I have ever used!!

by Christina10/20/2011

Been using it for years. Works great. Wish it was more natural...but oh well.

It works by Gigi from Hartwick, New York11/13/2012

This product is easy to apply to my non-cooperative cat, and it seems to keep the fleas away.

Flea Control by Ron from Lebanon, Pa.08/13/2013

I don't trust anything else but Advantage II flea control for my cats -- and Entirely Pets is the cheapest place to get it. Ordering & shipping were fast and easy. Thank You Entirely Pets!

Advantage for Cats - great product by Kristi11/21/2012

I have used Advantage for Cats for over 10 years, and our four cats have been flea-free for all of that time. Entirely Pets has the best price and product arrives soon after ordering.

4 MONTH Advantage ll Flea Control Small Cat by Pearl from Kitchener, ON04/13/2013

Best purchase ever no more flea needles.


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