Denestra™ with SAMe supports liver metabolic activity and proper liver function for dogs and cats. SAMe, or S-Adenosyl-Methionine, is a naturally occurring substance found in all living beings. SAMe in its biological form contributes to better pet health through a number of chemical processes: transmethylation, trassulfuration, and aminopropylation. These processes can affect liver and joint health in animals. Through the process of transsulfuration, natural SAMe is converted into a compound called glutathione, a potent antioxidant and liver detoxification tool. It supports normal detoxification and cleansing of the liver from impurities, which in turn may help the body from exposure to heavy metal or environmental toxins. Denestra with naturally occurring SAMe has added benefits for pet joint health as well. During the aminopropylation process, methylthioadenosine (MTA) is produced. MTA helps support cartilage matrix production in the joints, and may help maintain the effectiveness of proteoglycans, molecules that are critical for the lubrication of joints.
Denesta with SAMe is a pill that you administer orally to your dog or cat or may administer in a pill pocket to guarantee it is swallowed. With just one pill you can give your pet support for healthy normal liver and joint function at the same time. It can be used with prescription drugs.
Denestra should be swallowed and administrated on an empty stomach, one hour before or two hours after a meal (overnight fast is preferred). Do not cut or crush tablets. May be disguised in pill pockets for easier administration.
Maintenance Administration: Dosage may be increased or decreased at any time at the recommendation of your Veterinarian.
Liver Support by Rosiebearmom from Fort Worth, TX02/06/2013
My dog needed help with her liver. I am hoping Denestra will give her that support.
by from 11/15/2014
This is a 5-star product with a manufacturer problem. It appears the most recent shipment of 100mg SAM-e arrived in the Entirely Pets warehouse in open unsealed boxes in new blister packs that are too big for the package. All with a 2 month expiration date on the product.
Entirely by Pets from for3
buying by multiple from boxesKinda
Great for Senile Dog! by teddysmom from albuquerque, nm07/24/2013
This is a great product for my aging dog that's getting a little drifty. The price was more than excellent and shipping was quick!
hope it works as well as denosyl by Okie48 from Oklahoma02/18/2013
Our 12 year old dog has been taking denosyl for 4 years and it has effectively reduced her liver enzyme level to a reasonable number. Denosyl has not been available a couple of times when we've needed to place an order over the past year. We tried the milk thistle pill and were not happy with the size of it. This product is an acceptable size for our little Havanese to get down. This is important to us as all directions say not to cut or crush the pills. This is a less expensive alternative to denosyl, but I guess that the jury will be out on it until bloodwork is done to see if it's as effective.
Great Product-Great Price by Poppi from Issaquah WA11/25/2013
Sometimes it is difficult to find SAMe in 100mg tablets, with no additional ingredients. Denestra puts out a great product, Entirely Pet's pricing makes it very affordable.