EntirelyPets Online Pet Supply Retailer
Flat Rate only $4.95, Free Shipping over $85
Home > K9 Advantix® for Dogs > K9 Advantix II for Dogs > 
Home > Supplies for Cats > All Cat Supplies > Pet Supplies Plus by Brand > Bayer > K9 Advantix II for Dogs > 

K9 ADVANTIX II 12 MONTH Large Dog (for dogs 21-55 lbs)

K9 ADVANTIX II 12 MONTH Large Dog (for dogs 21-55 lbs)
K9 ADVANTIX II 12 MONTH Large Dog (for dogs 21-55 lbs)
Inset 1
Click to enlarge: Inset 1
View Larger
Item #ADTIXIIR12
Item Rating:
Regular price:$178.99
Sale price:$143.99 (You Save 20%)
Auto Reship Details
Enter Quantity:
Total Price:
FREE SHIPPING
on orders over $85


Send Page to Friend

Free Bayer OfferK9 Advantix II for Large Dogs up to 21-55 lbs

Keep your dog safe from irritating and dangerous pests with K9 Advantix II for Large Dogs weighing 21-55 pounds. Formulated for dogs seven weeks of age and older and weighing 21-55 pounds , K9 Advantix II outperforms its competitors not only by killing more varieties of pests, but also by repelling them to prevent future attacks.

Repels and Kills Ticks, Fleas, and Mosquitos

The active ingredients in K9 Advantix II help keep your dog safe from ticks, fleas, and mosquitoes. These effective compounds attack the pests' nerve cells, paralyzing and effectively killing them, as well as repelling them from future attacks. Most ticks are repelled and killed before they can attach, which may reduce the risk of transmitting disease-causing organisms to your pet. K9 Advantix II effectively kills and repels Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks.

Dog flea life cycle
Flea life cycle.View larger.

Fights Against Fleas at All Stages of Development

K9 Advantix II protects your pet against fleas at all stages of the parasite's development. K9 Advantix II breaks the flea life cycle by killing the living fleas on your dog before they can lay eggs. It also prevents the development of existing flea eggs, larvae, and pupae, helping to prevent future infestations.

K9 Advantix II also kills reinfesting fleas (newly hatched fleas jumping back on your dog) within two hours, and it prevents fleas on a treated dog from infesting your home.

Effective Against Biting Flies and Lice

In addition to complete tick, flea, and mosquito protection, K9 Advantix II also repels painful biting flies from feeding on your dog, and it effectively kills up to 100 percent of lice within one week of treatment.

Waterproof Formula

K9 Advantix II is waterproof, so there's no need to reapply after your dog has a bath or goes for a swim. Studies show that dogs are still protected against parasites after exposure to water, though for best results, dogs treated with K9 Advantix II should be bathed with a non-detergent shampoo.

Package Contents

Two boxes of six include 2.5-milliliter tubes of K9 Advantix II for Large Dogs up to 21-55 pounds.

K9 Advantix II Lifestyle shot
K9 Advantix II for Large Dogs
up to 21-55 lb
  • Kills and repels ticks, fleas, and mosquitoes
  • Repels biting flies and kills lice
  • Waterproof formula won't wash off from swimming or bathing
  • Includes twelve convenient one-month doses
  • Easy to apply
  • For dogs seven weeks of age and older and weighing 21-55 pounds
  • Per Dose: $10.92
K9 Advantix II and Frontline Plus Comparison Chart
View larger. Flea Cycle
The adult fleas you see are only a small percentage of the infestation. View larger.


K9 Advantix II is Available In:
Small Dog
(under 10 pounds)
Medium Dog
(11 - 20 pounds)
Large Dog
(21 - 55 pounds)
Extra-Large Dog
(over 55 pounds)
4 month
6 month
12 month
4 month
6 month
12 month
4 month
6 month
12 month
4 month
6 month
12 month




How to Apply

Applying K9 Advantix II to your pet is a fast and easy process. First, remove the K9 Advantix II applicator tube from its packaging and use scissors to peel down the foil. Next, hold the applicator tube in an upright position and pull the cap off the tube. Use the upturned cap to break the protective seal, and you're ready for application.

For easiest application, your dog should be standing upright. Evenly apply the entire contents of the K9 Advantix II tube to two or three spots from the back of the shoulder to the base of the tail. Part the hair at each spot until the skin is visible, then place the tip of the tube on the skin and gently squeeze out a portion of the solution. Be careful not to apply an excessive amount of the solution in any one spot, otherwise some of the solution might run off the side of your dog. Dispose of the container and do not reuse or refill. Do not empty unused product in any indoor or outdoor drain.

For optimal control and prevention of parasites, use K9 Advantix II every month. K9 Advantix II is available in four- and six-month supplies. Do not use K9 Advantix II on cats or any animals other than dogs.

Application Instructions

Evenly apply the entire contents of the tube to four to six spots on the top of the back--from the shoulder to the base of the tail. Apply monthly.

Length of Effectiveness

Under normal conditions, the product is effective for one month. However, in cases of severe flea infestation, retreatment may be necessary earlier than four weeks. Do not retreat more often than once every seven days. After flea control is attained, return to a monthly retreatment schedule.

Hazards to Humans

Causes eye irritation. Harmful if swallowed. Do not get in eyes or on clothing. Avoid contact with skin. Wash hands thoroughly with soap and warm water after handling.

Hazards to Domestic Animals

*For external use on dogs only.
*Do NOT use on animals other than dogs.
*Do NOT use on puppies under seven weeks of age.

Do not get this product on dog's eyes or mouth. Consult your veterinarian before using this product on debilitated, aged, pregnant, or nursing animals. Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become more severe, consult a veterinarian immediately. If your animal is on medication, consult your veterinarian before using this product.

Do Not Use on Cats

Due to their unique physiology and inability to metabolize certain compounds, cats must not use this product. If applied to a cat, or ingested by a cat that actively grooms a recently treated dog, this product may have serious harmful effects. If this occurs, contact your veterinarian immediately.

Environmental Hazards

This product is extremely toxic to fish. Do not add directly to water. Do not contaminate water when disposing of product or package.

First Aid

Have the product container or label with you when calling a poison control center or doctor, or when going for treatment.

If in eyes: Hold eye open and rinse slowly and gently with water for 15 to 20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice.

If swallowed: Call poison control center or doctor immediately for treatment advice. Have person sip a class of water if able to swallow. Do not induce vomiting unless told to do so by the poison control center or doctor. Do not give anything by mouth to an unconscious person.

If on skin or clothing: Take off contaminated clothing. Rinse skin immediately with plenty of water for 15 to 20 minutes. Call a poison control center or doctor for treatment advice.

To physician: Treat patient symptomatically.

Keep out of reach of children.

How long does K9 Advantix last?

A single application of K9 Advantix keeps working for one month.

How often should I use K9 Advantix?

Experts recommend monthly application to keep your dog protected year-round.

My dog is strictly indoors. Should I still use K9 Advantix?

Yes, ticks and fleas can be brought into the home by people or other pets--without owners even realizing it. Immature flea stages remain dormant until conditions are appropriate for development. This is why it is also important to protect indoor pets.

Can I bathe my dog during the month after application?

Yes, you can give your dog a bath. A non-detergent shampoo is recommended for best results.

How young can the dog be for application?

K9 Advantix is gentle enough for puppies as young as seven weeks.


Click here to see all reviews
4.61 rating based on 92 reviews
by Randy from Tennessee04/17/2012

Fast free delivery. Good price. Happy with our order.

Dog itched by Vince from MA11/28/2011

I have a 35 lbs Minature Aussie. We have had good luck with the origional K9 Advantix, but this new Advantix II, my dog was very upset with. He itched for days and was very unsettled. I am afraid to use the rest.

Great Prices on Advantix by Mrs. P from Danville, CA12/11/2011

Great prices found here! Love this website for flee/tick medicine for my two pugs!

Works without burning by Hanz' girl friday from San Antonio Tx12/01/2011

OK..so like everyone says things work well but this one has worked for us for many years...like about 8 years...switched to this as it covered ticks much better than other brands AND no site burning or hair loss. When I used another brand my dogs would go nuts trying to get rid of the burn at the multiple sites of application...plus we would still be picking off ticks...We feel confident with the use of this product

great product by Ronda03/30/2012

I have had as many as six dogs at a time. For years now I have been using this product It has never been a problem. No fleas, ticks or mosquitoes. No trying to get dogs to eat a pill . The only thing I would change is the packaging For old hands sometimes it is hard to get the little tubes out of the plastic, foil packages.

Giving it a Try !!! by Petlovertoo03/11/2012

I previously used Frontiline Plus on my dogs. Over the past year I have found it not to be as effective on fleas and ticks. Since we had such a mild winter, fleas and ticks will be rampant, so I switched to Advantix II in hopes of getting much better results.

No fleas - no ticks - no worries by Littlebird from Welcome, Texas03/07/2012

This is the best product I have ever used to preventive fleas and especially ticks from feasting on my dog. She is highly allergic to fleas and since using this product, have had NO issues with itching or "hot spots". Also, no more worries of her getting ticks. We live in the country with lots of deer and other carriers and I no longer have to worry about a tick problem!!! Thanks for the great product!!!!!

FLEALESS IN RI by ESKIE LOVER01/25/2012

NEVER ANY PROBLEMS WITH THIS PRODUCT, EASY TO USE, NO FLEAS EVER, GREAT AGAINST TICKS & SKEETERS.

KEY INGREDIENTS
Imidacloprid

Imidacloprid is an ectoparasiticide, an antiparasitic agent that targets parasites living primarily on the surface of a host. Chemically classified as a chloronicotinyl nitroguanidine, imidacloprid inhibits neurotransmitter transmission in insects, resulting in paralysis and death.

Benefits

Imidacloprid exhibits both adulticide and larvicidal flea efficacy; it not only kills adult fleas and larvae on your pet, but it also kills larval stages in your pet's immediate surroundings.

Main Purpose

To kill fleas at all stages of their life cycles and stop them from being able to move or feed.

Permethrin

Permethrin is the additional ingredient in Advantix. It belongs to the Type I class of pyrethroid acaricides and insecticides, and it also acts as a repellent. Pyrethroids affect muscle and nerve cells' sodium ion channels by increasing their mean open time, which leads to hyperexcitability and death of the parasite.

Benefits

Thanks to its repelling activity, permethrin reduces parasite bites and thus the risk of diseases and stress for your dog.

Main Purpose

To repel ticks, sand flies, and mosquitoes; to kill ticks and fleas.

Two Proven Ingredients with Enhanced Activity

Imidacloprid and permethrin work together to overwhelm the nervous system of the parasite, providing neurotoxic activity beyond that of each compound alone. This leads to more profound and quicker insect paralysis and death.

Specifically, imidacloprid increases the efficacy of permethrin by activating insect nerve cells and increasing the frequency of neurotransmissions. As a result, more sodium channels are opened and the pyrethroid can interact much better with its target site.


Pyriproxyfen

Pyriproxyfen is a pyridine-based pesticide. A juvenile hormone analog, it interferes with the hormone signaling of growing insects, so that insects in immature stages are unable to mature. Additionally, a female insect that touches the toxin will produce eggs that will not hatch.

Benefits

Pyriproxyfen provides an added layer of protection for pets and their surroundings. It interrupts the flea life cycle at multiple stages, halting the growth and development of insect eggs and larvae and preventing reinfestation.

Main Purpose

To prevent flea eggs from hatching and larvae from growing.

Active Ingredients % by Weight
Imidacloprid 8.80%
Permethrin* 44.00%
Pyriproxyfen 0.44%
Other Ingredients 46.76%
Total 100%
*cis/trans ratio: max 55% (±) csi and min 45% (±) trans
Net Contents

Twelve tubes, each 0.084 fluid ounces (2.5 milliliters)

RELATED ITEMS
K9 ADVANTIX II 4 MONTH Large Dog (for dogs 21-55 lbs)K9 ADVANTIX II 4 MONTH Large Dog (for dogs 21-55 lbs)Reg price: $64.99
Sale price: $49.99
K9 ADVANTIX II 6 MONTH Large Dog (for dogs 21-55 lbs)K9 ADVANTIX II 6 MONTH Large Dog (for dogs 21-55 lbs)Reg price: $89.99
Sale price: $72.99
K9 ADVANTIX II 4 MONTH Extra Large Dog (for dogs over 55 lbs)K9 ADVANTIX II 4 MONTH Extra Large Dog (for dogs over 55 lbs)Reg price: $64.99
Sale price: $50.99
K9 ADVANTIX II 6 MONTH Extra Large Dog (for dogs over 55 lbs)K9 ADVANTIX II 6 MONTH Extra Large Dog (for dogs over 55 lbs)Reg price: $94.99
Sale price: $73.99
Related items
Green Pet Fleaze-Off (8 oz)
Green Pet Fleaze-Off (8 oz)
Vita-Soothe Aloe & Oatmeal Shampoo (17 oz)
Vita-Soothe Aloe & Oatmeal Shampoo (17 oz)
Vitasone Spray with Hydrocortisone .5%
Vitasone Spray with Hydrocortisone .5%
Derm Tabs (120 Tabs)
Derm Tabs (120 Tabs)
Advantage II for Dogs
Advantage II for Dogs