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S Adenosyl 225 (SAMe) for MEDIUM / LARGE DOGS - 225 mg (60 tabs)

Item Number: S-ADEN22560
Regular Price: $76.99Sale Price: $49.89
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S Adenosyl 225 (SAMe) for medium to large dogs is used to improve liver metabolic activity and restore proper liver function. Contains antioxidants to help neutralize oxygen free radicals, amino acids to stimulate glutathione synthesis and reduce oxidative damage, B-vitamins to provide nutritional support ensuring proper protein and energy metabolism, and vitamin B-6 for synthesis of cysteine in the liver detoxification pathway. Unique, enteric-coated delivery system allows it to stand up formidably to stomach acid and effectively deliver the S-Adenosylmethionine 1,4 butanedisulfonate (SAMe) to the small intestine for proper absorption. Both strengths contain SAMe and other important ingredients for proper liver support such as milk thistle to help protect liver cells from toxins and reduce damage to those cells caused by some prescription drug use.

Usage Information

Dogs 20 to 40 lbs...............1 tablet daily
Dogs 41 to 90 lbs...............2 tablets daily
Dogs over 90 lbs ...............3 tablets daily

If feeding more than 1 tablet, divide daily dose between AM and PM. Tablets should be given on an empty stomach, at least one hour before feeding. Tablets are sensitve to moisture and extreme heat ans should not be split or crumbled.

SAMe (S-Adenosyl-L-Methionine) 225 mg
N-Acetyl L-Cysteine 40 mg
L-Taurine 33 mg
D-Alpha Tocopheryl Acetate 20 IU
Zinc Ascorbate 20 mg
Milk Thistle 40 mg
Pyridoxin HCI 16 mg
B-Complex Proprietary Blend 14 mg

Customer Reviews

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4.78 rating based on 9 reviews
Noticeable improvement for arthritis pain by Fester02/12/2013

I give these to my 15 year old corgi. We ran out, and after a few days I could definitely tell he did not feel as good and moved more stiffly. After re-ordering, he is back to feeling great, so I know this product definitely works.

Not delivered by Becky from Colorado06/24/2013

I placed this order about two weeks after my last order and it was mistakenly delivered to my old addresses. When I called.Entirely Pets, a company I have been a loyal customer of for quite a few years, I was told "too bad, so sad" Needless to say they lost my order and my patronage.

Great Service by GrammyK03/29/2012

I was very pleased with how quickly the product was delivered. Two days from start to finish!!!

Maggie's Protector by Vic from Centennial, CO11/02/2011

We must give our Aussie Shepherd mix many medications for her heart (Mitral Regurgitation). The SAMe helps keep her healthy and happy. Thank you Entirely Pets for making this product so readily available.

Good Purchase by Weimdogs03/19/2013

I purchased this product after finding out that my 7yr old adopted weim had elevated liver enzymes. He's been on this product for over a month along with a Hills Science Liver diet and some of his enzymes have decreased. I will continue to give this product in hopes of restored liver function!

Really Works by T. Hunt from San Diego, CA01/28/2012

I have 2 elderly dogs whose ALT counts had risen above normal. This brought both their counts back to normal. They will both be on it for the rest of their lives. There is no side effects. If there was, my one dog would have experienced them. My only suggestion would be to make a bottle with more than 60 tablets. I need to purchase at least one bottle month. It would help with multi-pet families if there was a bottle with 120 tablets in it.

by PJ10/31/2011

My vet recommended that my dog "Shadow" needed to take this for a liver enzyme problem. I had not found it any where they advised and the vet was currently out. So yes, very happy with this product. Shadow is a little friskier even though she is 13. I will be ordering this product again.

S Adenosyl 225/ liver disease by Angie from Arkansas03/02/2012

I am very pleased with this product and I received it in just a few days. This is the same meds that my vet tried to sell me at at about 1/2 the cost. My dog Murphy (14yrs) has to take one pill everyday to help the function of her liver.

price increase by Ted10/29/2011

I was a loyal customer until May of 2011. Thats when you increased the price of s-adenosyl 225 (60 tabs) for med. to large dogs, from $33.24 on 3-29-11 to 49.95 in May. That's such a jump in price that I figure that you must be overcharging on everything else you sell which is OK with me but I won't be buying it.

Good product by Butch04/10/2013

Seems to be doing some good. Plus the price is fair.

Cheaper than Human Sam-e by Apryl08/04/2008

I like this product because it is cheaper than sam-e you get in pharmacies and it works just as well. My pet has chronic high liver values due to chronic use of N-SAIDS (anti-inflammatories) for arthritis and she has cushings disease which also increases liver values and using s-adenosyl have brought her liver values down and has really helped protect her liver!


Questions and Answers

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Vitality Vet

NASC Certified

This product has met all of the stringent quality and safety standards set by the NASC.

The NASC (National Animal Supplement Council) is a non-profit self regulatory group that set specific guidelines to which manufactures must strictly adhere.

This seal is meant to minimize risk by providing an easy way of communicating to consumers that a product and its manufacturer meet particular standards of quality, customer safety and service.

Those products that have the seal for NASC Quality and Safety standards have been strictly audited and were determined as meeting the following criteria:

  • Consistent manufacturing quality control
  • A system for evaluating complaints and adverse events
  • Clear and accurate labels compliant with codes and restrictions for all forms of labeling
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