• Frontline Plus for Dogs 23-44 lbs - BLUE, 3 MONTH

    Frontline Plus for Dogs 23-44 lbs - BLUE, 3 MONTH

    Regular Price: $53.99Sale Price: $40.99
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    Temporary Price Reduction! FRONTLINE Plus Blue for Dogs 23-44 lbs

    Recommended by veterinarians, FRONTLINE Plus Blue for Dogs 23-44 pounds is a powerful and easy-to-use formula designed to quickly and effectively kill fleas, ticks, and chewing lice. FRONTLINE Plus is specially formulated for dogs weighing 23 - 44 pounds. Available without a prescription, FRONTLINE Plus only needs to be applied once a month for thorough pest control.

    life cycle of the commom flea
    Flea life cycle.
    View larger.
    life cycle of ticks
    Tick life cycle.
    View larger.

    Quickly Kills Fleas, Ticks, and Chewing Lice

    This powerful formula kills up to 100 percent of existing fleas in the first 12 hours after application, and it continues to kill new fleas for at least one month afterward. FRONTLINE Plus prevents the development of new fleas by destroying flea eggs and larvae and by destroying adult fleas before they have a chance to lay eggs. FRONTLINE kills chewing lice and all four major ticks, including ticks that may carry Lyme disease, keeping both your pet and your family protected.

    Waterproof Formula

    Thanks to its waterproof formula, FRONTLINE Plus won't rinse off when you give your dog a bath or when your dog goes for a swim. The active ingredient in FRONTLINE, fipronil, is stored in the natural oils in your dog's coat, so your pet is sure to stay protected no matter how many puddles he or she tramps through.

    EPA Registered Logo

    This FRONTLINE Plus product is EPA approved and registered, so it's guaranteed to be the exact same product sold by your Veterinarian. Click here for more information on EPA-approved pet products.

    Package Contents

    Box includes three 1.34-milliliter tubes of FRONTLINE Plus for Dogs.

    FRONTLINE Plus Blue
    for Dogs 23 - 44 lbs
    • Kills fleas, flea eggs, ticks, and
      chewing lice
    • Fast-acting formula
    • Includes three one-month
    • Waterproof formula
    • Easy-to-use applicator
    • For dogs weighing 23-44
    • Per Dose: $12.66
    More Info
    Got Fleas?

    A product guide to flea
    and tick products.

    Flea Facts You Should Know

    Interesting flea facts to help your
    pets be pest free.

    Fleas: Understanding the Enemy

    All about fleas and prevention.


    Helpful information on ticks and your

    FAQs about Fleas and Ticks
    Frontline Plus for Dogs Lifestyle shot
    FRONTLINE Plus for Dogs is Available In:
    (0 - 22 pounds)
    (23 - 44 pounds)
    (45 - 88 pounds)
    (89 - 132 pounds)
    3 month
    6 month
    12 month
    3 month
    6 month
    12 month
    3 month
    6 month
    12 month
    3 month
    6 month
    12 month

    Usage Info

    How FRONTLINE Plus Works

    Use FRONTLINE Plus for fast-acting, long-lasting flea and tick control. When you apply FRONTLINE, fipronil, the active ingredient, is stored in the oil glands under your pet's skin. It's then distributed continuously to the skin and hair of your pet through the hair follicles. This way, FRONTLINE provides waterproof, month-long protection against future pests while breaking down the flea and tick life cycles.

    Simple Three-Step Application

    Applying FRONTLINE Plus to your pet is an easy three-step process. First, remove the Frontline Plus applicator from the child-resistant package and cut or lift off the plastic tab to expose the foil and then peel the foil down. Next, hold the applicator upright and away from your face and body and snap off the tip. Finally, place the Frontline Plus applicator tip on the skin between your pet's shoulder blades and squeeze the applicator to apply the entire contents in a single spot onto your pet's skin.

    To prevent harm to you and your pet, read the entire label and enclosed directions before each use. Follow all directions and precautionary statements carefully.


    To prevent harm to you and your pet, read the entire label and enclosed directions before each use. Follow all directions and precautionary statements carefully. Always point the applicator away from your face, especially your eyes, and wash your hands thoroughly after application. USE ON DOGS ONLY. Do not use on rabbits or other animals.

    Weight Dosage
    Up to 22 pounds Apply contents of one applicator (0.67 milliliter) once per month
    23 - 44 pounds Apply contents of one applicator (1.34 milliliters) once per month
    45 - 88 pounds Apply contents of one applicator (2.68 milliliters) once per month
    89 - 132 pounds Apply contents of one applicator (4.02 milliliters) once per month
    All weights Apply contents of one applicator (0.5 milliliter) once per month




    Fipronil is a manufactured insecticide that works on a cellular level on adult fleas and ticks. It seeps into an insect's cells and blocks chlorine molecules from passing through. This stops the nervous system from working and paralyzes the insect.

    Fipronil kills adult fleas and ticks on contact or when consumed, and it can be spread from one insect to another.


    Because fipronil is so strong, it only needs to be applied once a month to continuously kill fleas and ticks. Once it is applied with an oily liquid to keep it on the skin of your dog, it slowly seeps into the hair follicles and oil glands where the fleas and ticks live.

    Main Purpose

    To kill adult fleas and ticks.


    Methoprene is an insect growth regulator, which means it works by affecting the eggs and larvae of fleas. It interrupts normal levels of growth hormone, preventing a juvenile flea from growing and molting, leading to death.


    Specifically designed to target developing larvae and eggs, methoprene prevents a flea population from increasing.

    Main Purpose

    To break the flea life cycle and stop further infestation.

    Active Ingredients % by Weight
    Fipronil 9.8%
    (S)-Methoprene 8.8%
    Inert Ingredients 81.4%
    Total 100%

    Some animals are sensitive or allergic to the ingredients in FRONTLINE, so be sure to watch for any signs of allergic reaction. If your pet shows signs of itching, restlessness, nausea, lethargy, or breathing difficulty, seek veterinary attention immediately.

    Net Contents

    Three tubes, each 0.046 fluid ounces (1.34 milliliters)

    Frontline Plus for Dogs 0-22 lbs - ORANGE, 6 MONTH6 Mo Frontline Plus SmReg price: $101.99
    Sale price: $77.99
    Frontline Plus for Dogs 0-22 lbs - ORANGE, 12 MONTHFrontline Plus for Dogs 0-22 lbs - ORANGE, 12 MONTHReg price: $202.99
    Sale price: $155.99
    Frontline Plus for Dogs 23-44 lbs - BLUE, 6 MONTHFrontline Plus BlueReg price: $102.99
    Sale price: $78.99
    Frontline Plus for Dogs 23-44 lbs - BLUE, 12 MONTHFrontline Plus for Dogs 23-44 lbs - BLUE, 12 MONTHReg price: $206.99
    Sale price: $158.99
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    Customer Reviews

    DISCLAIMER: The results described on the testimonials on this site, are the individual experiences and personal opinions of those who have purchased and used the products. These testimonials are not intended to make any claims that the products can be used to diagnose, treat, mitigate, cure or prevent any disease or medical condition.
    Click here to see all reviews
    by from 01/01/2013

    Great Product by Kim11/29/2011

    When trying to decide which flea/tick preventative to use on my pets, research put Frontiline Plus ahead of the rest. It kills fleas at all life cycles and also protects agains several other parasites. I have never seen a single flea on my pets since I started using Frontline Plus over 10 years ago.

    No Lasting Relief by Chuck M from Austin, TX07/13/2012

    The first application seemed to provide some relief, but within about a week they were back in force. The second application seemed to have no impact whatsoever.

    by Barb from Greensboro NC05/04/2013

    I have gotten Frontline Plus from Entirly Pets for several years and always pleased with the ordering as well as shipment.Prices are better than with any other company and I have really shopped around.My sister told me about this company and I have been very pleased.

    Frontlone Plus by kiki from West Palm Beach12/28/2012

    I bought Frontline Plus for my pet to keep fleas off of him all year long, this product work excellent , and is worth the money, i will buy again.

    Works Great!! by johnc66 from Raleigh, NC02/21/2013

    Have been using Frontline Plus on our Shiba Inu for the last 7 years. He has never had flea or issue.

    great flea stuff by candi from de07/31/2014

    my dog was itching like crazy before I bought this but after I put it on our beagle, with in a day he completely stopped. great product

    Works Every Time by Debby from Benton Harbor, Michigan10/05/2013

    This stuff never fails, and I can let my dog outside knowing he is protected with Frontline..

    Good Product by KinPA from E. Stroudsburg, PA06/18/2012

    Frontline Plus is a good product however, I like the fact that the K-9 Advantix II keeps the Fleas from even coming on my dog better.

    Very good product by Anna from Whitesville, NY03/27/2012

    Have used it for many years on all my dogs. Works great.

    Frontline by Sandy07/15/2013

    I bought two Frontline packages and received them in a timely manner. This was the first time I used Entirely Pets and was happy with my purchase.

    Frontline sub par results by Ramzzy from Rocklin, CA10/27/2013

    Like the rates shows, I gave it 2 out of 5 stars because the stuff is only fairly effective and doesn't work nearly as well as I thought & believe it should, especially considering the high pricing of the product...

    Best Price & Fast Delivery by HuskyBabies01/18/2012

    This is the best price for Frontline you're going to find. And the delivery was very quick. I was pleased and definitely recommend entirelypets.com!

    Frontline plus blue by marcia08/27/2012

    Frontline plus is very effective. Great shipping times.

    Frontline Plus for Dog by pkpilk10/11/2011

    This product is great!! I originally got it from my vet and paid double. Its awesome paying less for the same great product.

    Frontline Plus by Topsider from Connecticut08/04/2012

    Have used this product for years with great success.

    Works Great! by Rocky from Boynton Beach, FL01/17/2015

    This works great for my dog, a pug by the name of Rocky. All other products we have tried related to this have given him allergies. This one does not make him sick and kills the fleas.

    by shar12/12/2013

    have been using this for years, never had any issues

    Very good price! by Tator Hound from Norton, OH04/10/2014

    Shopping all sites and pet stores found best prices here!

    Frontline by BarkingBandits04/03/2013

    I think Entirely Pets has the best prices around for Frontline. Frontline works great on all three of my dogs. I never have a problem with ticks or fleas and I live in a wooded area.

    by JETTA06/04/2013

    I just can not get rid of the fleas. I have tried this product before and it worked but the last two years it is not working.

    by MOM from Vidalia, Georgia04/26/2012

    I was very happy with my purchase of Frontline Plus that I ordered for my lab and my golden retriever. I received it within 2 days after I ordered. I will continue to order all my pet needs from Entirely Pets. The price was very reasonable buying the 6 pack as opposed to the three pack. Thanks for your great service!

    Works better than anything else I've used by Chris W from Georgia09/08/2013

    Works better than the less expensive brands. Recommend it.

    A must-have by bbkatt from Dayton, OH10/24/2011

    Great price, speedy delivery and my little guy has been using Fronline Plus since he was old enough.. and he is almost 7 years old.. with no issues or problems. We live in a woodsy environment, and this product definately works!

    by from 07/31/2012

    Very happy with the frontline product for my dog and cat. Have never had a problem with fleas or ticks since using it. Your prices are very good and way below those of the local pet stores.

    by from Thanks."


    Frontline by johnc66 from Raleigh, NC02/22/2012

    Have used Frontline for 6 years now and never a problem.

    value by norainfl from Ormond Beach Florida02/20/2013

    In Florida flea preventative products are a necessity year round. I'm very satisfied with Frontline Plus. Also with the prices and fast service provided by Entirely Pets. I have a border collie mix-Yoshi- who is a Hurricane Katrina rescue. She deserves a good life after being what she's been through. Top on the list-not to be a flea buffet!!

    Frontline works by David from Christiansburg, VA11/30/2011

    I have been using Frontline products on my dogs for years and always had good results. I didn't know how good until I recently missed a couple of doses and found ticks on both dogs as a result. I won't let that happen again.

    It works by foots01/16/2013

    No fleas and only dead or dying ticks .Have 3 outside dogs in heavy tick country.

    works great by andi2634 from Pa10/10/2011

    reduction in fleas in 24 hours. I will order again.

    Frontline by Ricky09/20/2014

    On time and new brand product. Excellent. Good price

    Not so sure by rysgram from Sacramento, CA.10/31/2011

    I don't underdstand what is wrong, but I have used Frontline on my cocker for the last 6 years, and this order I reveiced from Entirelypets, does not seem to be doing the job! He is a house dog, not outside much at all, and now 2 weeks after using the product, he has fleas!! Not real happy, maybe the Frontline is old???

    Finally, Flea Free! by Randy02/20/2013

    What a saga! Fraught with fleas forever! But no - Frontline Plus to the rescue. And finally - my poor, long-suffering beardies are free at last.

    Love this online pet shop... by cotton from Oxford N.C.03/29/2012

    They have always ship the right item and the shipping is very fast. I know that I can depend on them for all my shopping. GREAT GREAT online pet shop.

    okay by burgurl12/01/2011

    frontline still works okay for ticks on my dogs; however it seems to have lost its effectiveness for fleas. i use the frontline in early spring during the worst of tick season (western north carolina) and then swtich to advantage II.

    Better than the others by Deby from Michigan10/15/2011

    Frontline is the best product for keeping flees off of my fur buddy. I have tried some of the others, but nothing works as well as the Frontline.

    Frontline for Dogs by Cheryl from Pacifica CA02/02/2012

    I have been ordering supplies from Entirely Pets for over 5 years, Not once did I have any problems and all the products i get are fantastic and fast delivery!

    Great Product by Rick from Rochester Hills, MI01/07/2012

    Have used this on multiple dogs for years. It works, it's reasonably priced and it's well packaged.

    Good Product by d51cowart from League City, TX12/31/2012

    This works well for keeping the fleas off my 3 dogs. You have to use it every month, though, if you live in Texas, or else the dogs get reinfested when they go outside.

    Is it asking too much? by Lukeys' momma10/10/2010

    I have been using Frontline Plus for over 5 years, & I am sorry to say that this is the first time I have a bonafide complaint on this product!!! I have a 38 lb. dog that is absolutely infested with fleas right now after using Frontline Plus (for up to 44 lbs) 'religiously' the week of the 15th of every month for over 5 years. I noticed at the end of this past August treatment, he was itching so I put it on a couple days earlier the month of Sept.; Now I just put it on his little itchy body again for this month of October, & started grooming him & found eggs, big, & little fleas everywhere!! I am just disgusted cause I do take great care because he is an indoor,"couch dog" & his bed is in my bedroom. I sacrifice to keep him in flea control, as I am laid-off & every cent counts. So Like I said, "Is it asking too much"...for at least my pets' flea control to work??..!

    another pest free friend by lolo from waldport or12/01/2011

    Both our dogs use this product. No fleas, no scratching and Vet preferred.

    Great Product by Shelsbells from Los Angeles, CA07/01/2014

    I've been using Frontline Plus for over a dozen years and swear by it. It always works. We've never had a flea or tick issue with either of our Chow Chows. This is a great product with no side effects that we've noticed.

    WORKS GREAT!!!! by Wendora07/25/2014

    I have tried other brands in the past, but Frontline works the best for us! We have had nothing but good results.

    It does the job by Zulu from NH05/30/2012

    Have used this for years and have not had an issue with ticks or fleas.

    Disappointed! by Sherrie01/24/2013

    I was very disappointed with this product. A full month after using it, I found a well-fed tick at the base of my dog's tail. I felt that it had been there long enough that the Frontline should have killed it. Also, he seems to still be bothered by fleas. I talked to my vet about it and am going to try Advantix next time. Lyme Disease is a real threat in my area, and even tho I do get my dog vaccinated for it, I still do not want to find ticks feeding on him.

    by Mopje from NH12/11/2011

    I have used Frontline Plus on my dogs for many years. Never have had a problem with ticks or fleas.

    Yuck! by Kempestuous from Seattle, WA07/07/2014

    We usually use Advantage, but since it was on sale I got the Frontline Plus. The next day after I put it on his back, the fur was still wet looking and clumped together. It never did go back to looking normal even after I brushed it multiple times over the next couple of weeks. In fact when I bathed him a few weeks later, I had to cut a whole bunch of the fur off of that spot because it was so matted. Our dog has pure white fur and no undercoat, so it's very easy to spot a flea. With Advantage the most I've ever seen on him is one. When I went to bathe our dog and looked through his fur, there were dozens of fleas and flea droppings everywhere on him for the first time in his life. I will never buy Frontline again!!!!!

    Reliable! by islalvr from Chicago, IL09/11/2013

    Frontline Plus remains the most reliable product in my opinion. I've found dead ticks on my dog's blanket, so it's definately working. Will stick with Frontline Plus.

    shipped as ordered by slim shaddy from Howell, Mi12/13/2011

    I ordered a 3 month supply of Frontline Plus and received what I ordered. I recently had an experience with another website of ordering the same item and they shipped another like item saying they were of of the original order because of supply and demand. Very happy with the service.

    Frontline Plus for dogs by MLH03/28/2012

    This is the best flea and tick control product I've found. I've tried all the others from the expensive name brands to the cheap generic ones. Frontline Plus keeps the flea problem under control.

    Simply the best by Bev07/03/2012

    Frontline Plus is the best product. Easiest to apply and Entirely Pets is the best place to get it. Only one place has it for less, but they mess up the order...so it's always Entirely Pets for me.

    Frontline Plus by oldgrayboy02/03/2012

    This site has the best price for Frontline Pluse that I have found. Shipping was fast.

    flea by laurie03/28/2008

    i love this product i use on all my pets i have 2 dogs and 1 cat it works wonderful and easy to use

    Great Product by Louann11/10/2009

    I have two dogs that I use this product on and it works great!. I live in Florida where the flea and tick cycle never really ends. So any product that keeps them flea and tick free, also keeps me and the house flea and tick free !

    Product and Price perfect by CBG02/28/2012

    Frontline is a great product that most pet owners are familiar with. This frontline order through Entirely Pets is the same great product but at an especially good price too. Good job Entirely Pets.

    A great, reliable, flea and tick medication by darma from Greensburg, PA10/25/2012

    Does the job great! A super product! This is the only flea and tick medication I order because I know that I can trust it to work on my dog Skye.

    Laura by Laura from Gibsonville, NC12/06/2011

    I've tried other brands, bad idea. We could not get rid of the 1 to 5 fleas on our dog. But then we used this in combination with a capstar. She is doing much better.

    Works for a few days only. by C. Jones from Virginia Beach, VA10/30/2013

    Does not work on my beagle mix, don't know if it's his coat or if the fleas are immune to it but it only lasted a few days. It used to work great a few years ago when we had a shepard but nothing we have tried has worked on the beagle so it might just be him.

    Frontline Plus by tacey04/02/2012

    I have used Frontline Plus since I moved to a wooded property. I was afraid my dog wood pick up a Tick and bring it in the house! Well, four years later,lots of Deer and other animals and, no ticks or fleas.... I won't change a thing! Thanks Frontline.........

    Works very well by cpapgal from Iowa06/19/2012

    We live in the counrty and have a lot of ticks and fleas in the area. Protects my dogs and keeps them healthy.

    Love My Doggies by Susan from Salem OR11/20/2012

    Frontline Plus is an awesome product and protects my dogs year round. No fleas on my dogs, no fleas in the carpet, no fleas on the furniture. And fleas LOVE to bite me, so I know if there's a flea anywhere around. Oh yeah, my dogs aren't spoiled or anything, but they do sleep on my bed. : ) So I'm very happy with zero fleas and no scratching!

    Flea Protection by crib from Orlando, FL05/07/2013

    It was a great product and it was my first time using it. My dogs seem to like it and thats what counts, keeping the pets happy!

    FrontlinePlus by cinntannbutter from Wallington,NJ12/07/2012

    Really works for my Dogs I would'nt fgo for other brands

    Best Bargain Ever by Missy10/28/2011

    A much better bargain for the same product as can be bought at the vet's office. Delivered within 5 days. Works great on my dog!

    The Best by Sue07/16/2012

    Ever since using this product, NO MORE FLEAS! It's better than others I have tried, because the odor seems to go away very quickly. And talk about Quick... The order arrived sooner that I thought it would!!!

    Frontline Plus for Dogs by Nan06/17/2013

    Product works very well and makes Missy happy to be flea free.

    A Must by Barb from San Diego, CA06/12/2013

    Living in CA this is a must all year long.

    by from 12/14/2013


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