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  6. Nutramax Denamarin Liver Health Supplement for Dogs, With S-Adenosylmethionine (SAMe) and Silybin, 75 Chewable Tablets

  • Close up of Denamarin tabletClose up of Denamarin tablet
  • Providing 24 mg of Silybin A plus BProviding 24 mg of Silybin A plus B
  • Recommended daily adminstration table by body weightRecommended daily adminstration table by body weight

Nutramax Denamarin Liver Health Supplement for Dogs, With S-Adenosylmethionine (SAMe) and Silybin, 75 Chewable Tablets

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NOTE: Limited supply item - only three (3) per customer per order.


Denamarin chewable tablets containing SAMe (s-adenosylmethionine) and silybin can be used in dogs of all sizes to help support healthy liver functions. In addition, research has shown the administration of Denamarin chewable tablets to be safe for dogs. Denamarin Liver Health Supplements are brought to you by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian recommended supplement company. *Source: Survey conducted among small animal veterinarians who recommended animal supplements.

Key Benefits:

  • Liver Support for Dogs: Denamarin is the #1 veterinarian recommended liver support supplement for dogs. This supplement contains s-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione - one of the liver's main detoxifying agents
  • High-Quality Ingredients: The Silybin found in Denamarin has shown better absorption by dogs than the standardized milk thistle extract found in many other products
  • Support Your Dog's Liver Health: The liver, one of your pet's most vital organs, is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system
  • From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
  • Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement


Active Ingredients:

S-Adenosylmethionine* 225 mg, Silybin-phosphatidylcholine complex (SPC) 82 mg. *Contains NMXSS75® S-Adenosylmethionine, proprietary veterinary researched specifications. Providing 24 mg of Silybin A+B.

Useful Information

Denamarin® Chewable Tablets should be given on an empty stomach, at least one hour before a meal for optimal absorption. The number of chewable tablets administered may be gradually reduced, or increased, at any time at the recommendation of your veterinarian.

Weight Daily Feeding
Under 6 lbs ¼ chew
7-15 lbs ½ chew
16-30 lbs 1 chew
31-45 lbs 1½ chew
46-60 lbs 2 chews
61-75 lbs 2½ chews
76-90 lbs 3 chews
91-105 lbs 3½ chews
Over 105 lbs 4 chews

Chewable tablets should be given on an empty stomach, at least 1 hour before a meal for optimal absorption.


Store in a cool dry place. Tablets are sensitive to moisture and extreme heat. Keep lid tightly secured to ensure freshness. Keep bottle out of the reach of children. This bottle may contain a non-toxic desiccant.

Customer Reviews

Review Summary
123 Reviews
81% (100)
11% (14)
3% (4)
0% (0)
4% (5)
94% Recommend this product (115 of 123 responses)
By Huili Q.
New York
September 14, 2022
good products
  • I like this products
By BobRob
Gilbert Arizona
Keeping My Ginny Alive
May 4, 2022
My 14 1/2-year-old miniature schnauzer has been on this medication for the last 10 years. I attribute her long life to this medication. It's been tough to find lately, but EntirelyPets has had it and at a competitive price. Thanks!
  • Sometimes can be difficult to find. Prices are increasing!
By Pam
Has helped ours dogs
March 2, 2022
We have used it with a Pomeranian and now a Brussels griffon. It has helped with mobility and even hair growth. Both dogs were elderly and had cushings disease. Definitely a great product
By Diana A.
Keeps my pup in the pink with a blue pill
October 11, 2021
This medical regime keeps my pup's liver enzymes in the normal range. IT WORKS.
  • Works
  • Too large for pup to swallow so cut it in half ... which she does not like the taste of.
By Eric
Las Vegas, NV
Great Product, Great Price
April 29, 2021
Great liver supplement. It was recommended by my vet for my pug. Found a much better price through entirelypets. Would definitely purchase again
  • Great price, quick shipping, solid liver supplement
  • Nothing I can think of
By chuck v.
good product
November 17, 2020
good product
  • good product
  • none
By Linda
Great for dogs with liver issues
September 15, 2020
My vet swears by this product and it has kept my dog’s liver issues in check for six years.
  • It works
  • None
By Ilse
Wstern, Maine
Vet recommended
April 23, 2020
My vet recommended Denamarin for our dog as her liver enzymes were elevated. After just one month, her levels had dropped to almost normal levels. I will keep her on this for sure!
By Regina M.
Helps my dogs liver
February 11, 2020
Blood work came back better after being on this.
  • Dog likes it.
By Cynthia
Omaha, NE
Great Product at a Great Price
December 29, 2019
Recommended by our Vet for our dachshund. She has been on this for several years and helps her liver condition. Great price!
Great Product!
August 17, 2019
My dog has been taking these for a few years now. Great product!
By Chris
Quick an easy
June 27, 2019
Easy to order and at a great price. Product arrived quickly. Very satisfied.
By Sharon
Cool, CA
Is improving my dogs liver enzyme levels
June 24, 2019
Have been giving this product for a few months now, and seems to be helping improve many of his liver enzyme levels.
  • Easy to give - he is a 60lb border collie, and he gobbles them up like treats.
  • none
By Jeannette
Anahuac, Texas
Denamarin chewable
June 23, 2019
I really like how my dog will readily take this medication.
  • Easy to give to my dog
  • None
By Darryl G.
Great product for High liver Enzymes ☆
June 14, 2019
Been using this product for my 12 year old Schnoodle with liver issues and it has done an Excellent job; Price is Very reasonable on Entirely Pets!
  • Good Price & Product
  • None as of yet!
By Donna
Scranton, Pa.
liver problems
June 4, 2019
This product helps my dog live a better life.
By Claudia
Iowa City, IA
Works great
June 3, 2019
Great price for a great product.
By Lufer
Maryville, TN
March 28, 2019
My terrier mixed breed dog refuses to ingest the product no matter how it is prepared (e.g., as a "chewable" tablet or crushed and mixed with virtually anything). Wish I had purchased pills vs tablet.
By Bonn
Review for Denamarin 225 mg for Dogs (75 Tabs)
December 10, 2018
2 vets & a vet internist have recommended Denamarin for my dog with kidney disease. We had difficulty with the caplets bc they were too large for my 6 lb. dog. When cut in 1/2, both halves must be given at once--company says they cannot be saved, and still be effective, for later. The chewables solved the problem, as portions of them can be saved. Neither of our dogs will eat them, but the co. said dosing with no more than 1 tsp. of wet food or similar is okay. This is working out well. d I do wish they were scored into 1/4s.
By Rappo
So Cal
Really Helps
September 18, 2018
Our little Kiwi is doing so much better now that we've gotten him on his meds! Thanks Entirely Pets
  • Keeps my Older Pup healthy
  • It can be expensive
By Goldice
Anchorage, Alaska
Wish I didn't have to...
May 17, 2018
I'm hoping that the choice I signed up for (repeat purchase automatically every month) is complete. Getting it from Entirely Pets is considerably less costly than getting it from my vet.
  • All
  • None
By Pam
Great value
October 6, 2017
With our dog having to take Denamarin for an extended time, Veterinarian recommended to purchase online. Economically, the 75 count is perfect for our current needs.
By Missy
Lake Wylie, SC
Be wary of FREE additional bottle
August 11, 2017
Although the expiration date on the purchased Denamarin wasn't until 2019, I now know why they're offering the FREE bottles of Denosyl with each order..... they expire NEXT month, 09/2017!!!
By Mahi
Good price and quick shipping
July 1, 2017
That is all that needs to be said.

Glad I found this site.
By Mw62
Oak hills, CA
Great liver support
June 4, 2017
My dog Ringo has atypical Cushing disease . Denamarin helped reduce the level of his liver enzymes and dramatically improved his health. Denamarin is a great product!
By Marge
Good Sale Price, Poor Expiration Date
June 3, 2017
Good price when on sale. Very disappointed that expiration date was 2 months from purchase date.
By Skeet
liver med
May 9, 2017
My girl has a slightly smaller liver so the vet recommended this product. She hadn't had any problems, so this is more a preventative. She's had no ill effects from it so I'm happy.
By Glen
Great for my senior dog
May 5, 2017
Improved his liver functions. He's 14 years old.
By Bootsie
Kirksville, Missouri
saved her life
May 4, 2017
Bootsie got her on very sick and had a enlarged liver. The vet put on this and 6 months she was back to herself
By Corgilover
Grand Lake, OK
Great Price
March 30, 2017
Already being a costly medication Entirely Pets saved me over 35% on an earlier order from another company. The standard free shipping had it at my home in 4 days.

Questions and Answers

1 Question & 1 Answer
from Cumberland, RI asked:
July 6, 2019
Just got this product do dogs really get to  swallow this pill?
1 Answer
This is a chew able tab and that means that they can chew this, so they don't have to swallow it. 
Submitted by: Customer Service on August 15, 2019