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  6. Nutramax Denamarin Liver Health Supplement for Dogs, With S-Adenosylmethionine (SAMe) and Silybin, 75 Chewable Tablets

  • Close up of Denamarin tabletClose up of Denamarin tablet
  • Providing 24 mg of Silybin A plus BProviding 24 mg of Silybin A plus B
  • Recommended daily adminstration table by body weightRecommended daily adminstration table by body weight

Nutramax Denamarin Liver Health Supplement for Dogs, With S-Adenosylmethionine (SAMe) and Silybin, 75 Chewable Tablets

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NOTE: Limited supply item - only three (3) per customer per order.


Denamarin chewable tablets containing SAMe (s-adenosylmethionine) and silybin can be used in dogs of all sizes to help support healthy liver functions. In addition, research has shown the administration of Denamarin chewable tablets to be safe for dogs. Denamarin Liver Health Supplements are brought to you by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian recommended supplement company.*Source: Survey conducted among small animal veterinarians who recommended animal supplements.

Key Benefits:

  • Liver Support for Dogs: Denamarin is the #1 veterinarian recommended liver support supplement for dogs. This supplement contains s-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione - one of the liver's main detoxifying agents
  • High-Quality Ingredients: The Silybin found in Denamarin has shown better absorption by dogs than the standardized milk thistle extract found in many other products
  • Support Your Dog's Liver Health: The liver, one of your pet's most vital organs, is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system
  • From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
  • Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement


Active Ingredients:

S-Adenosylmethionine* 225 mg, Silybin-phosphatidylcholine complex (SPC) 82 mg. *Contains NMXSS75® S-Adenosylmethionine, proprietary veterinary researched specifications. Providing 24 mg of Silybin A+B.

Useful Information

Denamarin® Chewable Tablets should be given on an empty stomach, at least one hour before a meal for optimal absorption. The number of chewable tablets administered may be gradually reduced, or increased, at any time at the recommendation of your veterinarian.

Weight Daily Feeding
Under 6 lbs ¼ chew
7-15 lbs ½ chew
16-30 lbs 1 chew
31-45 lbs 1½ chew
46-60 lbs 2 chews
61-75 lbs 2½ chews
76-90 lbs 3 chews
91-105 lbs 3½ chews
Over 105 lbs 4 chews

Chewable tablets should be given on an empty stomach, at least 1 hour before a meal for optimal absorption.


Store in a cool dry place. Tablets are sensitive to moisture and extreme heat. Keep lid tightly secured to ensure freshness. Keep bottle out of the reach of children. This bottle may contain a non-toxic desiccant.

Customer Reviews

Review Summary
218 Reviews
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95% Recommend this product (208 of 218 responses)
By Huili Q.
New York
September 14, 2022
good products
I like this products
By Jess
He's eating again 🙂
August 29, 2022
I am very satisfied with this product. We found out one of my dogs has a tiny liver and it was working overtime to process his food. These pills help his liver function and now he eats every meal.
By BobRob
Gilbert Arizona
Keeping My Ginny Alive
May 4, 2022
My 14 1/2-year-old miniature schnauzer has been on this medication for the last 10 years. I attribute her long life to this medication. It's been tough to find lately, but EntirelyPets has had it and at a competitive price. Thanks!
Sometimes can be difficult to find. Prices are increasing!
By Pam
Has helped ours dogs
March 2, 2022
We have used it with a Pomeranian and now a Brussels griffon. It has helped with mobility and even hair growth. Both dogs were elderly and had cushings disease. Definitely a great product
By Huili Q.
new york
perfect product perfect price
February 25, 2022
good products
By Diana A.
Keeps my pup in the pink with a blue pill
October 11, 2021
This medical regime keeps my pup's liver enzymes in the normal range. IT WORKS.
Works Too large for pup to swallow so cut it in half ... which she does not like the taste of.
By Huili
new york
perfect product perfect price
June 16, 2021
perfect product perfect price
By Mary
Phenomenal product
June 8, 2021
My 15 YO pekingese had become lethargic and did not have much interest in eating. Blood work showed liver enzyme were elevated. I began giving her this product and within 3 days she was dramatically improved. Her energy was amazing!!!!! She tootled around the house like she was a puppy. Her appetite returned to voracious levels. Her liver enzymes returned to normal. We continued to give this to her long term.
Rapidly effective. Easy to give in small dab of cheese. Must wait 1 hour after giving product before dog can eat.......poor baby!
By Eric
Las Vegas, NV
Great Product, Great Price
April 29, 2021
Great liver supplement. It was recommended by my vet for my pug. Found a much better price through entirelypets. Would definitely purchase again
Great price, quick shipping, solid liver supplement Nothing I can think of
By Cindy M.
Very good medication.
April 25, 2021
This has brought my dogs liver counts back in line and using them everyday keeps them there.
Easy to give. Animal can't eat for over a hour after giving.
By Jan
Crawford, tx
Cat saved by Denamarin!!
December 24, 2020
My 12 year old kitty had high enzymes. 1000 in oct. started Denamarin thru vet and had him checked in nov. enzymes down to 400 and in December Down to 200. On meds and will go back in January. Do daily meds plus vitamins with iron and prednisone. Improvement! Cat looks good! Has bright eyes and all is functioning better. He is eating and more active! Thank you!
By chuck v.
good product
November 17, 2020
good product
good product none
By Devoted P.
Dallas, TX
Supports healthy liver!
September 26, 2020
I have been using this product for years on various pets with liver disease. My most recent is a 14 year old minature toy fox terrier that was diagnosed with hepatic carcinoma in 2018. She underwent chemo and radiation and has been in remission since mid 2019. I started her on Denamarin on the advise of her oncologist and her liver values have been very stable since her remission date. I now give this to some of my other senior fur babies to help boost their aging liver issues.
Yucaipa, Ca
Denamarin Meds
September 22, 2020
It appears that it is helping my Gordon Setter Liver function. Good product.
Merchant Response:We feel the same way about your pros and cons. Wish it wasn't so expensive, but it's a difficult substance to produce. It oxidizes rapidly once exposed to oxygen. Great care is taken during manufacturing including doubling the active amount as well as entracoting and blister packing. Take care GBG!
Reasonably priced for this med/ Still a bit pricy
By Linda
Great for dogs with liver issues
September 15, 2020
My vet swears by this product and it has kept my dogs liver issues in check for six years.
It works None
By Neal T.
Purchase of Denamarin
April 27, 2020
Great price and quick delivery. What more can you ask for.
see above no cons
By Summerbuff
Wilmington, NC
Works great!
April 24, 2020
My vet recommended this product to reduce my dogs ALT and it has definitely helped.
Effective Easy to administer No side effects Expensive but worth it and Entirely Pets has the best price
By Ilse
Wstern, Maine
Vet recommended
April 23, 2020
My vet recommended Denamarin for our dog as her liver enzymes were elevated. After just one month, her levels had dropped to almost normal levels. I will keep her on this for sure!
By Kenton B.
Dog Liver Function Decline
April 10, 2020
My Hannah's liver (she is 12) started declining in function last year (Please do a complete blood panel on your pups every year!). My Vet recommended Denamarin as the first course of treatment. It really helped improve her enzyme numbers. Now she is also on an additional med and we have stabilized or really slowed the decline of her liver function. She is active, happy and eating well.
An expensive product but liver blood screens showed it to be very effective in my case.
Merchant Response:Beautiful Denamarin testimonial Kenton. Be well
Effective in my dog's case. Expensive.
By Regina M.
Helps my dogs liver
February 11, 2020
Blood work came back better after being on this.
Dog likes it.
By Paul B.
Quick Delivery, Good Price
December 31, 2019
Exactly what the vet wanted for our dog. Delivered quickly at a good price.
By Cynthia
Omaha, NE
Great Product at a Great Price
December 29, 2019
Recommended by our Vet for our dachshund. She has been on this for several years and helps her liver condition. Great price!
By Brenda W.
Denamarin for Cats and Small Dogs up to 12 lbs (30 Tabs) Was: $36.99 Sale Price: $27.99
December 28, 2019
Helped my Stella's liver numbers go down,
Great Product!
August 17, 2019
My dog has been taking these for a few years now. Great product!
By Chase
Excellent service
June 30, 2019
Quick very easy transactions will keep purchasing from entirely pets.thank you
All good None
By Chris
Quick an easy
June 27, 2019
Easy to order and at a great price. Product arrived quickly. Very satisfied.
By Sharon
Cool, CA
Is improving my dogs liver enzyme levels
June 24, 2019
Have been giving this product for a few months now, and seems to be helping improve many of his liver enzyme levels.
Easy to give - he is a 60lb border collie, and he gobbles them up like treats. none
By Jeannette
Anahuac, Texas
Denamarin chewable
June 23, 2019
I really like how my dog will readily take this medication.
Easy to give to my dog None
By Hope
Brooklyn NY
June 21, 2019
I give this product everyday to my dog Brooklyn. Vet recomended this for her liver. It keeps her healthy.
Helps with your dogs liver function.
By Darryl G.
Great product for High liver Enzymes ☆
June 14, 2019
Been using this product for my 12 year old Schnoodle with liver issues and it has done an Excellent job; Price is Very reasonable on Entirely Pets!
Good Price & Product None as of yet!

Questions and Answers

1 Question & 1 Answer
from Cumberland, RI asked:
July 6, 2019
Just got this product do dogs really get to  swallow this pill?
1 Answer
This is a chew able tab and that means that they can chew this, so they don't have to swallow it.
Submitted by: Customer Service on August 15, 2019