GlycoFlex 2 Canine (120 Tablets)

Item: GLYCOII120
Compare to: $59.99
You Save: $14.00!(23%)

NASC Certified

This product has met all of the stringent quality and safety standards set by the NASC.

The NASC (National Animal Supplement Council) is a non-profit self regulatory group that set specific guidelines to which manufactures must strictly adhere.

This seal is meant to minimize risk by providing an easy way of communicating to consumers that a product and its manufacturer meet particular standards of quality, customer safety and service.

Those products that have the seal for NASC Quality and Safety standards have been strictly audited and were determined as meeting the following criteria:

  • Consistent manufacturing quality control
  • A system for evaluating complaints and adverse events
  • Clear and accurate labels compliant with codes and restrictions for all forms of labeling


GlycoFlex 2 offers a comprehensive support for joints and connective tissue health that helps with recovery from sprains, joint injuries, and as a follow-up to orthopedic surgeries. Stage 2 contains perna canaliculus, glucosamine HC1, DMG (dimethylglycine), MSM (methylsulfonylmethane), and manganese for added joint support. MSM also provides added comfort during recovery. This formula is designed specifically for moderate stages of joint dysfunction. GlycoFlex 2 - Rebuild

For use in dogs only.

  • Comprehensive support for connective tissue health
  • For adult and mature dogs as well as sporting, hunting, and working breeds
  • Helps rebuild normal joint function as part of follow-up to orthopedic surgery
  • For dogs with moderate joint dysfunction
  • DMG is used to support proper immune response, cardiovascular and skin health. It can also help reduce stress and has anti-inflammatory properties.
  • Chicken liver flavored chewable tablets for easy administration
  • Available in a 90 and 120 count bottle


Active Ingredients Per Tablet:
Glucosamine HCl (Shrimp and Crab) 750 mg
Perna canaliculus (GlycOmega™ brand Green-Lipped Mussel) 600 mg
Methylsulfonylmethane (MSM) 500 mg
N,N-Dimethylglycine HCl (DMG) 100 mg
Manganese (Mn Amino Acid Chelate) 10 mg

Inactive Ingredients: brewers yeast, natural imitation chicken flavor, silicon dioxide, stearic acid.

Useful Information

Initial: (4 - 6 Weeks)
Up to 30 lbs: 1/2 tablet daily
31 - 60 lbs: 1 tablet daily
61 - 100 lbs: 2 tablets daily
101 lbs and over: 2 1/2 tablets daily
Maintenance: (After initial period)
Up to 30 lbs: 1/2 tablet every other day
31 - 60 lbs: 1/2 tablet daily
61 - 100 lbs: 1 tablet daily
101 lbs and over: 1 1/2 tablets daily

If giving more than 1 tablet, divide between AM and PM.

CAUTION: Safe use in pregnant animals or animals intended for breeding has not been proven. If lameness worsens, discontinue use and contact your veterinarian. Administer during or after the animal has eaten to reduce incidence of gastrointestinal upset.

WARNING: For animal use only. Keep out of the reach of children and animals. In case of accidental overdose, contact a health professional immediately.

Store in a cool, dry place.

Customer Reviews

48 Reviews
90% (43)
8% (4)
2% (1)
0% (0)
0% (0)
94% Recommend this product (45 of 48 responses)
By PuppyMommy
April 16, 2019
Great brand
I have been trying different joint health supplements to find the one that works best for my pup. I have used the GlycoFlex brand before and pup loved the flavor but the chews got stuck in her teeth. She loves the chewable tablets and I am seeing a huge improvement!
By Happy
February 3, 2016
Great Product!
Years ago (1996) I had a 15-year-old German Shepherd, Lady, with severe arthritis. I thought I was going to lose her. My vet put her on Glyco Flex, and it got her up and going for about 5 more months. A few years later (1999), I lost Chloe, an Australian Shepherd mix, to arthritis. Glyco Flex helped her, but eventually I lost her. For each of these dogs I waited until they were having problems to start them on Glyco Flex.. After losing Chloe, I decided to start all of my dogs on Glyco Flex at age 6 before they developed problems. None of the four dogs I've had since Chloe and Lady have developed the mobility problems that Lady and Chloe had, and they have all lived to be 13 or more years. My current two dogs are 13 and 15. They are active, climb stairs well, and chase squirrels. The pills are easy to give--just drop them in their food. I am pleased with and highly recommend Glyco Flex. I think it is the primary reason I have not lost another dog to arthritis.
By Buster's M.
May 31, 2015
Have Used for Many Years
Started using Glyco Flex about 15 years ago at the recommendation of out vet. I've used it for 3 dogs so far. It does seem to help with joint issues.
By patric
March 8, 2015
Review for GlycoFlex 2 Canine (120 Tablets)
I don't think my Great Pyr would have made through this long, cold winter without Glyco Flex11. This product really helps reduce her arthritic limitations.
By Border C.
Dallas TX
July 30, 2014
Effective essential
Been using some form of this product now for 20+ years. My dogs work or compete in sports. Would not consider having one of these dogs without this stuff supporting their joints. I believe it keeps them in competitive form, and then gives them relief as they get older.
By Mia
New Port Richey,Fl.
July 21, 2014
Been using Glycoflex for over 10 yrs
My chihuahua Mia had Patella Fluxation Surgery in 2004 at age 2. I have had her on Glycoflex since the surgery. The Vet said she would be Arthritic by age 7. Mia is now 12 yrs old and runs and jumps and loves to ride with us on the Harley!!! She still has the flexibility of a much younger pup :) Thank You Glycoflex for making Mias life wonderful!
By July
Shelby, NC
June 13, 2014
Great product!
July was born with what we thought was bad hips, but after X Rays, it turned out to be her knees. Glyco Flex has helped her to move about much better. She is 7 years old now and she does most anything she wants.
By AllDogsGoToHeaven
June 3, 2014
Great for Joint Maintenance
I first purchased this product from my Vet. Entirely Pets has the best prices. And I notice the difference if my older or working dogs aren't on this.
By Smithers
St Louis
April 7, 2014
Some improvement
My almost 11 year old dog has been taking this product twice a day for six weeks. She has some serious arthritis. I haven't seen a miraculous improvement as some folks have stated, but she does seem more spry, so her joints must be hurting somewhat less.
By joy
Blue Ridge Mountains
January 5, 2014
This product is a miracle in a bottle. I began giving this product to my 14.5 year old, 80# Lab/mix and the nearly-immediate difference in her walking was incredible. She's still pretty stiff when she first gets up, but once up she moves quickly, confidently and even hobby-horses back from our walks. A fabulous product, and worth giving a try.
By vik
November 6, 2013
Glycoflex II
My dog has hip displasia, and is about 10 years old. After 2 weeks of using this product, my dog can get around much better. Seems better every day....much more active. She seems to be gainning more muscle tone in the leg with the hip displasia again.
Entirelypets is a wonderful web site with great service.I use them alot.
By kushnivas
Ottawa, ON
October 28, 2013
Good starting place for a dog with sore hips.
First time using this product. My boy does not like it as a chewable, but doesn't mind it mixed in his food. After using it for a couple of weeks, I could see an improvement in his mobility. I will continue to use it and will decide whether it is right for him after a couple of months. So far I am satisfied with current progress.
By DogMom
October 11, 2013
Great Product!
We have 3 dogs on 2 different types of Glycoflex products. One is a senior Rottweiler & the other 2 are mature age dogs under 15 lbs. this supplement has had amazingly positive effects on all of them. It takes a few weeks to see the results but its well worth the wait. We strongly recommend this supplement to any pet owner who has concerns or a diagnosis of joint problems in their animal.
By cherokee
September 24, 2013
good price
My Black Lab was on this for 7 or 8 years. I swear it kept her going, she just passed away in July at the age of 16 years and 3 months. My Vet asked me what I did too keep her going, I said Glyco- Flex. I truly miss my baby girl
By Zia's M.
Roanoke, VA
August 16, 2013
Glyco-flex II
I've used this product for several years as a step between Glyco-flex I and III. My dogs are very active and I feel it helps them stay healthy and able to move freely.
By Jo
August 3, 2013
Great product for an aging dog!
I have used this product for several years for my dog with arthritic hips. It helps her to move around better. I recommend it highly!
By Lizzy's M.
July 22, 2013
Worked well
My dog can walk again plus she likes the taste. It's like a treat for her!
By Nanci
Mtn View, Ca.
July 20, 2013
Great Product
My dog has been using this product for 7 years, and I like the pricing and packaging for the Glyco Flex. Competitive rates, too!
By Kallie's m.
Belleville Mi
July 17, 2013
glycoflex II
I am using this as a preventative. I used the III level on my arthritic dog and it appeared to help.
By Rick
June 5, 2013
Already Effective!
I have been giving my dog, Bodi, a 7yr old Vizsla, Glyco-Flex II for approximately one month. Started because he was showing a shoulder problem. In one month I believe we are already experiencing positive results. We will continue this therapy and now that summer is here he can begin swimming so I expect even better results. Thanks!
By Tina
April 24, 2013
Amazing results
I would definitely recommend this product to anyone with a active dog. Our younger dog hurt her leg while running, vet talked about surgery, but we decided to try Glyco-Flex ll first and I am so glad we did. The leg healed and our dog avoided surgery. Also recommend G-F lll for older dogs, amazing product.
By Jo
Bowling Green,KY
March 19, 2013
Great deal!
My dog has used this product for several years. This is the first time I ordered it from Entirely Pets. Great price and speedy delivery. I will definitely order from Entirely Pets again. Thank you for your great service!
By Sprig
Houston, TX
February 12, 2013
Have used for a long time
I have used Glycoflex II for quite a while with my older dog, now 19 and recently switched to Glycoflex III. My 10 year old is on Glycoflex II. Both dogs were/are active in agility.
By Itzhak
Royal Oak, MI
February 10, 2013
What I expected for less
I buy from here because it ends up costing about 10 dollars less than my vet wants for the same product (After shipping)

Always happy with the shipping time and process.
By Mac
January 22, 2013
It helps to keep our older dog moving better and hopefully, he has less discomfort.
By dolphin
South Bend, IN
December 15, 2012
Good for my dog
It help my dog. My vet recommond this product for my dog but it cost too much at vet but found your company that l can afford. My dog is happy and l am happy too. Thank You dolphin
By Doll
December 10, 2012
Review for GlycoFlex 2 Canine (120 Tablets)
It's a little early to say, but I think my oldest dog may be doing even better on this Glyco-flex II than she did on the regular Glyco-flex.
Since I give (4) of our (5) dogs either the Glyco-flex regular or the Glyco-flex II now, the difference in buying from the vet or from EntirelyPets is sizeable.
Thank you for helping me take care of my pets!
By AussieMom
San Diego, CA
November 25, 2012
Noticed a Difference
My 8 yr old Aussie had been transiently limping on his front legs.( He regularly runs through the neighborhood canyons and trails.) My vet prescribed Rimadyl but I found it to be too strong and read about side effects( I don't like giving him meds anyway). I was shopping for a joint supplement and decided on Glyco Flex II after reading the reviews. We have been using it for almost a year and have noticed a significant improvement in his gait - rarely have I seen him limping! I'll continue using Glyco Flex for the rest of his life!
By dolphin
August 21, 2012
Good for my dog
This product does really help my dog alot. And it cheaper than at vet. office
By cherokee
July 16, 2012
glyco flex II
This product has been keeping my black lab going strong for 3 years, she is 15 years now

Questions and Answers

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3-PACK GlycoFlex 2 (360 Soft Chews)3-PACK GlycoFlex 2 (360 Soft Chews)Reg price: $123.99
Sale price: $94.89
6-PACK GlycoFlex 2 (720 Soft Chews)6-PACK GlycoFlex 2 (720 Soft Chews)Reg price: $230.99
Sale price: $176.99
2-PACK GlycoFlex 2 Canine (240 Tablets)2-PACK GlycoFlex 2 Canine (240 Tablets)Reg price: $118.99
Sale price: $90.99
3-PACK GlycoFlex 2 Canine (360 Tablets)3-PACK GlycoFlex 2 Canine (360 Tablets)Reg price: $179.99
Sale price: $137.99
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