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  6. 3-PACK Denestra SAMe 200 mg (180 Tablets)


3-PACK Denestra SAMe 200 mg (180 Tablets)

Item: SAME600MG180
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Denestra™ with SAMe supports liver metabolic activity and proper liver function for dogs and cats. SAMe, or S-Adenosyl-Methionine, is a naturally occurring substance found in all living beings. SAMe in its biological form contributes to better pet health through a number of chemical processes: transmethylation, trassulfuration, and aminopropylation. These processes can affect liver and joint health in animals. Through the process of transsulfuration, natural SAMe is converted into a compound called glutathione, a potent antioxidant and liver detoxification tool.

It supports normal detoxification and cleansing of the liver from impurities, which in turn may help the body from exposure to heavy metal or environmental toxins. Denestra with naturally occurring SAMe has added benefits for pet joint health as well. During the aminopropylation process, methylthioadenosine (MTA) is produced. MTA helps support cartilage matrix production in the joints, and may help maintain the effectiveness of proteoglycans, molecules that are critical for the lubrication of joints.

Denesta with SAMe is a pill that you administer orally to your dog or cat or may administer in a pill pocket to guarantee it is swallowed. With just one pill you can give your pet support for healthy normal liver and joint function at the same time. It can be used with prescription drugs.

For Use In: Dogs & Cats

    Key Features:
  • 100mg active SAMe
  • Supports Liver
  • Supports Joints
  • Cognitive Function
  • Stabilized Enteric Coated Tablets


Ingredients: S-Adenosyl-L-methionine disulfate p-toluensulfonate, Microcrystalline cellulose, Mannitol, Carboxymethylstarch sodium salt, Colloidal silica anhydrous, Glycerol behenate, Magnesium stearate.

Coating Ingredients: Methacrylic acid copolymer, Glycerol palmitostearate, Medium chain triglycerides, Titanium dioxide, Colloidal silica anhydrous, Talc, Triethyl citrate, Yellow iron oxide (III).

Useful Information

Animal Weight Daily
16-35 lbs. 1 Tablet
36-65 lbs. 2 Tablets
66-99 lbs. 3 Tablets
Over 121 lbs. 4 Tablets

Denestra® should be administrated on an empty stomach, one hour before or two hours after a meal (overnight fast is preferred). Do not cut or crush tablets. May be disguised in treats for easier administration. Dosage may be increased or decreased at any time at the recommendation of your Veterinarian.

CAUTIONS: If animal's condition worsens or does not improve, stop product administration and consult your Veterinarian. In case of accidental overdose, contact a health professional immediately.

WARNINGS: For use in animals only.

STORAGE: Store in a cool dry place. Keep out of reach of children and pets. Keep tablets in their original blister pack until used. Tablets are sensitive to moisture and extreme heat.

Customer Reviews

Review Summary
2 Reviews
50% (1)
50% (1)
0% (0)
0% (0)
0% (0)
100% Recommend this product (2 of 2 responses)
By Tom
Dallas TX
All was great
January 4, 2017
We have used Denestra from some time and it appears to be a fine product.

Our EntirelyPets order was delivered quickly and in good condition.
By Angie
Albuquerque, New Mexico
Don't have a lot to say
February 1, 2013
I can't really say a lot about this product because, like Denosyl, I use it as a supplement to strengthen my dog's liver, since he is being treated with phenobarbital due to epilepsy. The only issue I've had so far is that because of the size of tablet and the fact that it cannot be cut, Benji has thrown it up on a couple of ocassions. Denestra is much larger so I prefer Denosyl for Benji.

Questions and Answers

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3-PACK Denestra SAMe 100 mg (180 Tablets)3-PACK Denestra SAMe 100 mg (180 Tablets)Reg price: $66.99
Sale price: $50.99
Denestra SAMe 200 mg (60 Tablets)Denestra SAMe 200 mg (60 Tablets)Reg price: $51.99
Sale price: $39.59
Denestra SAMe 400 mg (60 Tablets)Denestra SAMe 400 mg (60 Tablets)Reg price: $64.99
Sale price: $49.49
3-PACK Denestra SAMe 400 mg (180 Tablets)3-PACK Denestra SAMe 400 mg (180 Tablets)Reg price: $181.99
Sale price: $139.99
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