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  6. Advantage II Small Cats 5-9 lbs.|Vet-Recommended Flea Treatment & Prevention|6-Month Supply

Advantage II Small Cats 5-9 lbs.|Vet-Recommended Flea Treatment & Prevention|6-Month Supply Video

Advantage II Small Cats 5-9 lbs.|Vet-Recommended Flea Treatment & Prevention|6-Month Supply

Item: 5461677
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Deliver total flea protection to your cat or kitten with Advantage II Small Cat. This vet-recommended, topical treatment and prevention formula kills adult fleas, flea larvae, and flea eggs on contact within 12 hours of application - meaning fleas can be eliminated before they bite or lay new eggs. Effectively break the flea life cycle, control existing flea and lice infestations, and prevent further infestations with one simple application. Advantage II Small Cat flea protection is effective on both indoor and outdoor cats. Your cat should be at least 8 weeks old and weigh 5-9 lbs. to use Advantage II Small Cat.

Advantage II Small Cat is a trademark of Elanco or its affiliates.

Key Benefits:

  • Advantage II Small Cat is a leading brand in cat flea treatment and prevention for small cats 5-9 lbs., at least 8 weeks of age
  • Vet-recommended, easy-to-apply monthly topical treatment – no hard-to-swallow pills, no prescription needed
  • Delivers total flea protection – kills adult fleas, flea larvae and flea eggs through contact
  • Same-day effectiveness – kills fleas within 12 hours of application and keeps working for 30 days
  • Fragrance-free formula, waterproof after 24 hours of application


Active Ingredients by Weight
Imidacloprid 9.10%
Pyriproxyfen 0.46%
Other Ingredients 90.44%
Total 100.00%

Useful Information

View Advantage II for Cats product label.

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

How To Open

  1. Be sure tube is at bottom of pouch.
  2. Using scissors, cut the pouch across the top and remove tube.

How to Apply

  1. Remove one applicator tube from the package. See "How to Open" section
  2. Hold application tibe in an upright position facing away from you and your pet's face and eyes. Pull cap of tube.
  3. Turn the cap around and place other end of cap back on tube.
  4. Twist cap to break seal, then remove cap from tube.
  5. Part the hair on the neck at the base of the skull until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. Do not get this product in your cat’s eyes, or allow your cat to ingest this product. The product is bitter tasting and salivation may occur for a short time if the cat licks the product immediately after treatment. Treatment at the base of the skull will minimize the opportunity for the cat to lick the product. Do not allow the product to run off.
  6. Discard empty tube as described in Storage and Disposal.
  7. Under normal conditions this product is effective for a month. However, in cases of severe flea infestation, retreatment may be necessary earlier than four (4) weeks. Do not retreat more often than once every fourteen (14) days for kittens or once every seven (7) days for small and large cats. After flea control is attained, return to a monthly retreatment schedule.


  • Use only on cats or kittens 8 weeks and older. Do not apply to cats or kittens weighing less than 9 lbs. Do not use on other animals.
  • Do not apply more than one (1) tube per treatment, even for larger cats.
  • Do not have contact or allow children to have contact with treated area until completely dry.

Storage and Disposal

Do not contaminate water, food, or feed by storage or disposal.

Pesticide Storage:

Store in a cool, dry place inaccessible to children and pets.

Pesticide Disposal and Container Handling:

Nonrefillable container.

If empty:

Do not reuse this container. place in trash or offer for recycling if available.

If partly filled:

Call your local solid waste agency or 18004229874 for disposal instructions. Never place unused product down and indoor or outdoor drain.


Harmful if swallowed. Causes moderate eye irritation. Avoid contact with eyes or clothing. Wash hands thoroughly with soap and warm water handling. Keep out of reach of children. Do not contaminate feed or food.

Hazards to Domestic Animals

For external use only.Do not apply to cats or kittens 8 weeks of age or weighing less than 9 lbs. As with any product, consult your veterinarian before using this product on debilitated, aged, pregnant or nursing cats. Individual sensitivities, while rare, may occur after using ANY pesticide product for cats. If signs persist, or become more severe, consult a veterinarian immediately. If your cat is on medication, consult your veterinarian before using this or any other product.

Possible Side Effects

Monitor your cat after application. Side effects, although very rare, may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Gastrointestinal signs such as hypersalivation, vomiting or diarrhea have also been reported. If these or other side effects (such as lethargy) occur, consult your veterinarian or call 1-800-422-9874.

Customer Reviews

Review Summary
142 Reviews
81% (115)
13% (19)
2% (3)
0% (0)
4% (5)
95% Recommend this product (135 of 142 responses)
December 21, 2020
By Deborah
Lakewood, NY
Great product to prevent fleas
October 27, 2020
We use this every month and never see fleas!
  • It works!!
  • Maybe the smell. Not really any cons though!
By Rich
Sparta, MI
Great Products & Services
June 7, 2019
Good stuff
By SoftCat
Works for my cat
October 13, 2018
Advantage 2 works for my cat and I'm glad that they make the 2 month pack available to buy!
By Kiks
San Diego
Works fantastic!
April 10, 2018
This works perfectly, and my cat is not bothered by it at all. People need to realize that the flea has to BITE the animal for this to work. It doesn't kill your neighbor's fleas until the jump on your cat and BITE your cat, which then kills the flea. Continuous use will eventually kill all fleas, because 1 flea lays a zillion eggs...
By Multiple O.
Bad Experience
September 19, 2017
Simply doesn't work. I have several cats and all of them are scratching and itching within a week of application. What makes it worse is that I have my lawn treated to kill fleas and ticks as well.
By Gary K.
New Westminster, B.C.. CANADA
Flea treatment
August 25, 2017
Killed fleas very quickly, some what difficult to apply
By Pug
Advantage II Friends highly recommended
January 7, 2017
I have not started the cats on this yet I have to wait until due date for their previous treatment to start this one! But am anxious to see how this works out
because it has been so highly recommended to me!
By Pet L.
South Carolina
Great product!
January 1, 2017
Does the job and much better price than what you would pay at your vet's office.
By BobbyW
San Rafael, CA
Works Well But...
November 12, 2016
I have found that I need to reapply every three weeks instead of four. Otherwise it's a great product to control fleas on my cats.
By Mary
Southern Vermont
2 Month is Perfect Amount
November 6, 2016
I always use Advantage ll. Really like that a 2 month amount is offered. Perfect for someone living on a monthly budget.
Problem Solved
November 3, 2016
Relax your pet. Take it slow. Give the solution time to absorb. You'll be happy!
By Allie
Excellent product
October 26, 2016
Have used it for a few years now and our cat has been flea tick free. Best product I have ever used for flea tick control
By Taz
Cincinnati, OH
Advantage II Flea Control
October 23, 2016
This product got rid of all the fleas within days. Received A lot faster than I thought and great price.
By Lui S.
Great flea control
August 11, 2016
Works quickly, keeps fleas from infesting both cats & house. We've had reactions from other topicals, one cat gets a chemical burn, the other seems very sleepy and subdued for a few hours. No reaction at all with Advantage!
By mmn1
monroe, nc
Must-Have Purchase
July 12, 2016
Thank goodness for Advantage II Flea Control for my rescue cats. And thank you for your speedy shipment.
By Sallie J.
Auburn WA
Advantage II
May 3, 2016
The Advantage II Okay. My cats are still stretching
By very g.
Review for 12 MONTH Advantage II Flea Control for Small Cats (5-9 lbs)
November 25, 2015
You can use him dog ..It is not irritating at all.
By Chelsea M.
Statesville, NC
No more fleas!
September 15, 2015
My cat who was feral has struggles with fleas for a year. I have tried everything for both of my cats. sprays, shampoos and collars. they all seem to have temporary relief. This worked like a charm. My cats haven't had a problem with fleas since! and It's a great price.
By Daniel
Long Island New York
Works Great
September 2, 2015
I have tried other flea products that did not work well after starting my cats on Advantage II Flea Control they do not scratch or itch also when I
comb them with a flea comb I did not find any fleas
best flea control I have used so far
By foster m.
Bridgeport, CT
4 MONTH Advantage II Flea
August 10, 2015
I was very happy with the topical treatment it works well for my cats.
By Tom
Vista, CA
Advantage II For small cats
July 8, 2015
We have been using Advantage II for small cats for at least 6 years and have been very pleased with the protection it provides.
By Bernie
Good value
June 16, 2015
I found this to be best price for this product. I have used Advantage II on my cat for a few years and found it really does the job of keeping him flea free.
By SFcats
shawnee forest in southern IL
Works Well!
June 14, 2015
I use it all year. Keeps my kitties happy and healthy!
Great product and service.
By Joe
Advantage II Cat Flea Control
May 11, 2015
So far it's working OK; no visible fleas.
By Chelsea
Troutman, Nc
No more fleas!!!
April 6, 2015
My two cats have had fleas for awhile. I've tried baths, collars and medicine from Walmart. Then I ordered this and after months and months of failed attempts my cats were finally flea free!
By Dee
San Diego, CA
Big Advantage in Cat Care!
April 2, 2015
We have used Advantage on our outdoor/indoor cats for over 20 years and we have never had any fleas or ticks on the pets or in the house.
By sunshinewholoves
easy purchase great deal
March 19, 2015
received in timely manner
easy to use was nice smelling not like others
started working quickly noticed dead fleas in a few hours
would buy again
By Bazinga
Oahu, Hawaii
It works
March 3, 2015
I find this flea prevention works the best. The only thing I don't care about flea prevention products is they are messy. Trying to separate the hair to reach the skin while trying have kitty sit still is tricky. Mine already run when they hear the cap come off! lol Then I learned that you should hold kitty for a few minutes after applying until it sets. Otherwise, kitty will shake and it goes everywhere! Once on, it gets rid of the fleas!
By Susie
Washingto State
Works For Me!
February 17, 2015
I foster shelter cats, so it's important to keep my own free of pests. This works for me! Shipping is really fast!

Questions and Answers