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  6. Zymox Plus Otic Advanced Formula w/ Hydrocortisone 1.0% (1.25 oz)

Zymox Plus Otic Advanced Formula w/ Hydrocortisone 1.0% (1.25 oz) Video

Zymox Plus Otic Advanced Formula w/ Hydrocortisone 1.0% (1.25 oz)

Item: IMW039971
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Zymox Plus with BioFilm Reducing Formula works on resistant microbes quicker and more effectively.

Zymox Plus helps animals with acute and chronic otitis externa due to resistant pseudomonas and similar biofilm forming microbes. This condition is caused by harmful microbes that form complex biofilm, including: Pseudomonas, Staphylococcus aureus, Coagulase-negative staphylococci, Methicillin-resistant Staphylococcus aureus (MRSA). Zymoc Plus destroys the difficult to penetrate biofilm and breaks the cycle of chronic infection by increasing the potency of the antimicrobial LP3 Enzyme System, as well as four additional enzymes. Try this formula if your pet continues to suffer from infection, or has an infection that will not heal. Apply into the ear of your dog or cat once a day without cleaning the ear before or during use.

  • Aids in the treatment of chronic otitis externa
  • For dogs and cats

  • How to Use:

    Shake well before use. Apply liberally to un-cleaned ear, filling the ear canal. Gently massage and work into infected area. Wipe to remove excess. Allow the animal to shake head. Use 1x daily for 5- 14 days. Safe for extended use on persistent cases. Contraindicated in cases of ruptured or punctured eardrums. Not for use on pregnant or lactating females. Keep out of reach of children. For Animal Use only.


    Hydrocortisone (1.0%) ... Anti-inflammatory

    Useful Information

    Shake well before use. Apply liberally to un-cleaned ear, filling ear canal. Gently massage and work into infected area. Wipe to remove excess. Treat once a day for 7 days, 14 days for chronic infections. Safe for extended use on persistent cases.

    Do not use on punctured ear drums.
    Do not use on pregnant or lactating females.
    Do not use in conjunction with other topical ear medications or ear cleaners.
    Do not allow water in or near ear during use.

    If condition persists or worsens, consult your veterinarian.

    Keep out of reach of children. Store at room temperature.

    Which Zymox Otic to Use
    Features and benefits:

    1.0% HC

    DVM or pet owner seeking antibiotic alternative X X X
    Noage restrictions of the pet X X X
    Non species specific X X X
    Can be used in conjunction with oral meds X X X
    No side effects X X X
    Easy, 1x daily administration- squirt, rub, done X X X
    No cleaning before or during use X X X

    Pet is allergy-prone X X
    Plays in water X X
    Lives in humid enviroment X X
    Ocasional otitis X
    Unknown cause/no culture X X
    Exotics or rabbits X
    Pregnant or lactating females X
    Maintenance and prevention X X

    Inflammation is apparent with:
    Bacteria X X
    Fungal/yeast X X
    Polymicrobail X X

    Presistant, unresolved otitis or recurring infections from complex biofilm forming microbes:
    Bresistant Pseudomonas X
    Resistant Staph X

    Customer Reviews

    Review Summary
    38 Reviews
    95% (36)
    3% (1)
    3% (1)
    0% (0)
    0% (0)
    100% Recommend this product (38 of 38 responses)
    By Marie
    New Hampshire
    Vet Recommended
    September 30, 2020
    My dog seems to get chronic ear irritations. He will shake his head many times / day, and though there was no "infection", there was a small build-up, so our Vet recommended this product. We use it for 7 days and it seems to alleviate the problem.
    • Very Pricey
    By Jack
    Zymox plus
    July 12, 2017
    This is the only product I have ever found that has actually worked. My cat had chronic ear problems for most of his adult life and this has given him some relief in that last year that I have been using it.
    By Bower
    Works better than the Vet
    May 21, 2017
    I spent a lot of money going to the Vet with no resolve. My dog's ears are great after using this product.
    By Big D.
    Best I've Found
    May 3, 2017
    I was a little skeptical at first but started using it as directed and such a GREAT and IMMEDIATE improvement! We tried everything from vet pills/drops to otc treatments. Wicked happy I got this product! I feel you won't be disappointed!
    By Timie
    Katy, Texas
    Best so far
    December 29, 2016
    I have tried everything to get rid of the black junk in my dogs ear. This is the only thing that comes close. It does not get rid of it completely but almost.
    By Susan
    Webster, NY
    The ONLY Thing That Works!
    October 21, 2016
    Zymox Plus has been the salvation for our poor dog's chronic ear issues. We went through the "vet route" -- antibiotics (several rounds), special ear wash, and prescription ear drops (one of which caused our dog to lose her hearing for 4 months). Nothing beats Zymox Plus. If you are discouraged with the lack of results and GIGANTIC vet bills from prescription treatments of chronic ear issues, please give Zymox Plus a try. You will NOT be disappointed!
    By LuvShepherds
    Webster, NY
    AMAZING PRODUCT!!!!!!!!!!
    September 25, 2016
    This is an AMAZING and life-changing product. We had used Zymox for years on one of our German Shepherd's that had chronic ear issues...It was the ONLY thing that worked for him -- after hundreds of permanent resolution. Then, when we were at our wits' end....we discovered Zymox Plus. WIth consistent use -- as directed on the product, our dog's ears have cleared up. We are so very thankful for this product....and will sing its praises to all that will listen. Thank you for offering a natural product that works wonders.
    By Wendy
    Philadelphia, Pa.
    Zymox Plus Otic-HC works
    April 27, 2016
    I recently realized I've been getting prescription Mometamax for six years with barely a result. My friend recommended I try Zymox Plus so I did. One bottle helped and the second bottle I bought and just started finished the job. For the first time in many years my dog's ear is clean. This product is amazing.
    By Fall
    worth trying
    February 8, 2016
    Our Springer has had chronic ear problems for a long time and we've tried a lot of things. A couple vets thought we should do surgery (Total Ear Canal Ablasion). I decided to try to manage his symptoms. His left ear is looking very good. His right ear is questionable, but tolerable, I think. We're told he has pseudomonas behind his ear drum. Since this product appears to help control his symptoms, I will be continuing to use it.
    By Cathy
    Works Great
    January 15, 2016
    Zymox ear drops helps my dog better than any other product we've tried.
    By smoochie
    Thank Goodness!
    August 11, 2015
    After trying several other products coming off the the vet shelf that didn't quite get the job done; this product just works. Real relief for my 13 yr old labradoodle finally.
    By Susan
    Canyon Lake, Texas
    Great product for chronic ear issues
    June 3, 2015
    I have two Schnauzers, one with grain allergies and she is prone to get ear issues even on grain-free foods. I am so glad I can order this product on line for use when she does get an ear issue. I've been to the vet numerous times and every time, there is no answer, just a big bill and this same product. Now I can safely treat my Nugget's ear issues when they do arise and no additional vet bill! After a week of treatment, her ears are good as new!
    By Deb
    San Carlos, California
    Zymox Enzyme Solution
    April 13, 2015
    So far so good. My 11 year old Mastif and rott mix dog Titan, keeps getting ear infections, so my vet recommended the solution. :)
    By jtmi
    Houston, Tx
    Works Well
    January 20, 2015
    This is a great product that works really well. My dogs hate any type of medication, and they don't love getting this one, but it is easy to give to them and works quickly.
    By bulldog l.
    January 16, 2015
    These drops cured my English bulldog's chronic ear infection. Love it!
    By PAGirl
    Pittsburgh, PA
    so glad i found this
    July 15, 2014
    Zymox Plus works great, I have a lab with allergies and always getting ear infections, this is so much cheaper than the meds. from the vet and it works overnight she is also always licking her paws making them really red at times. I put this on her paws at night and by morning they are nice and pink again. Even though this doesn't say it is for paws.
    By Midgriffith
    Middletown, Ohio
    Best stuff ever!
    June 29, 2014
    By day two of usage Simon ear had cleared up the itching had stopped and we were sleeping again. Thank you so much!
    By stella
    this stuff is the best
    May 30, 2014
    Our dog Stella had constant ear problems! She would shake her head and scratch her ears until they would bleed! They would balloon up and it would be back to the vet. The only solution the vet had was surgery but with no guarantee that it would stop her. We searched for our own solution and came across zymox plus otic enzymatic solution. We bought it hoping it would just give her a little relief. We used it for a week but within the first 2 days it had already dramatically reduced her shaking and swelling! It was amazing! At the end of the week her bad ear looked almost better then her good ear! I don't ordinarily write reviews but my dad said we needed to let everyone whose dog has bad ear problems that there is hope out there. Thank you to the makers of zymox for giving relief from constant ear problems to Stella and us. Hopefully this helps everybody! We will be using this if he ear problems ever return!
    By Kat
    Love this Product
    May 23, 2014
    This is the BEST medicine I have ever used on my dogs ears. Poor guy has gone through so many products and trips to the vet to no avail, but this stuff really does work. I would highly recommend it.
    By Ricardo
    Houston, TX
    April 10, 2014
    This works exactly as it says it does. My english bulldog had a bit of an ear infection & i used this as directed & it did it's job to perfection. Will definitely be buying some more.
    By waterchick60
    Zymox HC Soln a 10 out 0f 10.
    March 29, 2014
    My Labrador had very bad ear infections, After numerous attempts with antibiotics and steroids I asked a friend for advice. She said they used Zymox because it was not an antibiotic but an enzyme formula that "ate" the bacteria. My labs ears have been clear with only a touch up application 1 to 2 times a week.
    By ana
    like magic
    March 27, 2014
    After suffering for what seems like ages from persistent ear infections and having been treated with several products, this is the one to finally solve the issue for our dog. Very happy!
    By Pumpkin's M.
    Troy, IL
    BEST EVER !!!!!!!
    February 9, 2014
    I would give this product 25 stars, if I could. My dog has been suffering with itching ears and skin issues for 6 years. She has been on prescription Atopica and a wide range of other products. I had even thought about having her put to sleep because she was soooo miserable. The vets were not able to help much and BELEIVE me we were at their office or on the phone with them many times for these issues. I used this product and saw a difference on the first day. The second day, I did not give the dog any benadryl, the antihistimine I was using to keep her itching under control. I can not say enough good things about this product.I bought the shampoo, the rinse and also the topical cream with the HC. All have been GREAT. I will pass this information on the my vet.
    By DRS
    SJU PR
    November 30, 2013
    This is the best product one can find for ear infections.
    By YorkieMom
    I think it's a great product, but my dogs hated it
    September 24, 2013
    Ear scratching, but no smell. Usually use Malecetic Solution, but both my guys have an array of allergies. Figured I try something new. I don't know if the gel-like consistency bothered them, but they both hated it. I continued to use it for the next 3 days, but only by apply it to a q-tip and going into the canal ever so slightly. After they shook their heads, I wiped the product all over the pink of the ears with a cotton ball. It did help them not to scratch, but it was a trial to use. Went back to Malecetic.
    By Texas D.
    East Texas Piney Woods
    Zymox liquid for Dog's ears
    July 2, 2013
    Our Catahoula suffered with Otitis Externa, constantly scratching her ears. Just one application of Zymox cleared up the itch. She is now a happier dog.
    By Ozzie
    New Jersey
    June 12, 2013
    As usual ZYMOX products are excellent.
    I use ZYMOX PLUS Otic HC with my
    cocker Spaniels and sometimes with few
    clients if need it.
    100% quality if you purchase the product.
    By GC
    One Week
    June 10, 2013
    On and off again frequent ear infections in my pet dog's ears were gone in one week. It is nice to find a product that does what it says it will.
    By traif
    Boca Raton, FL
    great product
    May 7, 2013
    My poodle, gets ear infections quite regularly, and this helps clear it up
    By Dawn
    Glad I found it
    March 20, 2013
    When regular Zymox didn't seem to be clearing my dogs ears up, this one did the trick...thank goodness. I used all 3, since this is with HC I don't like to use it too much, so I alternated with regular Zymox without HC and then used the Zymox cleanser to flush the ears once they start getting better, now I am doing the flush a couple times a week so it hopefully doesn't come back.

    Questions and Answers

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