1. Home > 
  2. Dog Supplies > 
  3. Ear & Eye Products > 
  4. Ear Cleansers & Treatments > 
  5. Zymox Otic > 
  6. Zymox Otic w/ Hydrocortisone 1.0% (1.25oz)

Zymox Otic w/ Hydrocortisone 1.0% (1.25oz) Video

Zymox Otic w/ Hydrocortisone 1.0% (1.25oz)

1. Select type:
2. Select size:


Zymox Otic with hydrocortisone is used for the treatment of acute and chronic otitis externa, an inflammation of the outer ear characterized by itching, swelling, redness and pain in the outer part of the ears. Simply touching the ears of your pets can hurt.

Zymox Otic is manufactured by PKB Animal Health, a well-known manufacturer of pet care and veterinary products. It is a proven antibiotic alternative and provides quick relief for your pet and also eliminates the bacteria and fungi that caused the infection. It is safe to use long-term and is especially beneficial for persistent cases of otitis externa. Zymox Otic without hydrocortisone is also available for those who are sensitive to hydrocortisone or those pets who are pregnant or lactating.

It is important not to pre-clean your pet's ears before applying Zymox Otic. The ear may be gently wiped with a soft cloth to remove excess.


Active Ingredient: Hydrocortisone 1.0%

Other Ingredients: Benzyl Alcohol, Dextrose, Glucose Oxidase, Glycerin, Hydroxy Propyl Cellulose, Lactoferrin, Lactoperoxidase, Lysozyme, Potassium Iodide, Propylene, Glycol, Purified Water.

Useful Information

Shake well before use. Apply liberally to un-cleaned ear, filling ear canal, Gently massage and work into infected area. Wipe to remove excess. Apply once a day for 7 days, 14 days for chronic infections. Safe for extended use on persistant cases.

Customer Reviews

335 Reviews
92% (308)
7% (23)
1% (3)
0% (1)
0% (0)
96% Recommend this product (321 of 335 responses)
By Michelle
Mooresville, NC
October 11, 2019
Have never seen anything that works like this. Ear problems are no longer a problem with your pet with this product.
ProsSafe, extended use if needed. WORKS WONDERS!
Wesley Chapel, Florida
July 27, 2019
Best for ear infections on dogs and cats
Have used this product prescribed by
my veterinarian for several of my dogs who have had ear infections through the years!

It cures the infection and inflammation

I highly recommend this product!
ProsIt works!
By Copper
January 14, 2019
Zymox Otic with Hydrocortisone works great!
Bassets need their ears cleaned often, but my basset hound has skin issues and still gets red irritation in his ears at times anyway. I use Zymox and massage in. He stops shaking his head and scratching at his ears. It works great! Thanks for saving us another vet visit.
By Rudi
May 18, 2018
Great product
This product works really well for persistent yeasty ears
By Big L.
Ontario, Canada
September 5, 2017
This Works
My black lab had a bad ear infection that did not respond to Mometamax from the vet. I Tried home remedies, too. The ear would almost clear up but infection kept returning during two months. Zymox Otic with Hydrocortisone 1% from EntirelyPets.com finally CLEARED UP THAT PROBLEM in seven days. I plan to get another one just to have it on hand in the future for immediate treatment. Thank you!
By Paula B.
Wilmington NC
May 31, 2017
THIS IS BY FAR SO MUCH CHEAPER THAN GOING TO THE VET AND GETTING A PRESCRIPTION. This worked immediately and no cleaning of the ear before applying. My lab had a nasty ear infection and it was gone in 2 days.
By manon
quebec, canada
May 11, 2017
good product
IT not the fist time i buy that product it s very good but i wont need it anymore becose my dog is dead i received my package 2 days after is dead so i have 2 bottles but no more dog
By Christina0328
April 2, 2017
Great for inflammed dog ears,redness & head shakin
My dogs ear has been inflammed and red and he kept shaking his head until his ear would bleed. I ordered this product to try and and it worked in one day.the next day his ear went down and wasnt so red.I kept putting it in his ear for about a week and now its completely gone. I recommend this product if your dog has a ear infection or dirty ears or redness and swelling.it helps alot!
By Rich c.
March 31, 2017
Single most important product sold ! Never take your dog to the vet for an ear infection again . It's that simple !!
By 29star
March 14, 2017
Review for Zymox Otic (1.25oz) with Hydrocortisone (1.0%)
Good product. Does a great job clearing up kitty's itching ears and seems to soothe at the same time. Highly recommend.
By PapaWayne
January 11, 2017
The Real Deal
Zymox absolutely 100% lived up to the hype! It did what it was supposed to do and all the other rave reviews were accurate! Two treatments and all symptoms stopped. Our dog had been frantically scratching his ears miserably, but this stuff worked FAST!
By Dog&CatOwner
January 9, 2017
Great Product
I have used this for years to help clear up my dogs' ears. Since using this, I know longer have to go to the vet for antibiotics. I would highly recommend.
By BostonLover
Deltona, FL
January 5, 2017
The first time I used this is when I got it from a vet to clear up an ear infection in the one of my dogs. When I saw this on your site then I snagged it so I could keep it on hand when I notice that my dogs start scratching their ears and when they have a brownish waxy stuff coming from their ears. If your dogs get an infection, stay away from cleaning their ears and only apply this in their ears for at least 7 to 10 days till the infection is gone.
By Jerry
Bernhards Bay,NY
October 28, 2016
this is great when used properly. keeps me from the Vet every other month. haven't had my dog to the Vet only for his check ups in 2 years. and it is very reasonable in price.
By duncan
Buffalo NY
October 23, 2016
V/G Product
Zymox Otic works like a charm on our dog...Priced right with Quick ship....
By noname
October 21, 2016
Can't recommend this enough. Easy to use and works great.
By Marcie
October 21, 2016
Works Great!
I purchased Zymox Otic for my Great Dane who has had issues with his ears. This product worked great and you will see a difference within a few days. Saved a lot of money by not having to go to the vet and his ear infection is gone. I love the fact that you do not have to clean the ears before applying the drops, my guy is never happy to have his ears messed with, so this worked out great for both of us.
By Deena
August 8, 2016
Great product
This works much better thank what I was sold at the Vets plus it's a lot cheaper. My dog seems to tolerate it better than the other also since it doesn't have to be refrigerated.
By bobarnes
peachtree city ga.
August 2, 2016
Zymox otic with 1.0 hydrocortisone
after many months of self treatment and trips to vet,purchased zymox,followed directions and in less than 4 days,ear discharge and smell was eliminated.i will never be without this product for my Labs !!! Could not imagine my vet not recommending this product. I had to reasurch on line to find myself.Very happy for Bongo and myself.
By Wally
June 27, 2016
Great product
The price was better than most. The medication took care of the ear problems right away.
By Royalyouch
June 23, 2016
This product is really works!
This product is really works! Cure my dog ear in 2 days. Highly recommended!
new haven, connecticut
May 3, 2016
Zymox Otic with Hydrocortisone
I've been using this for about 2 years now. It is amazing how fast it works! Within a day there is a huge difference. Ive shared this with several friends and they think its a miracle too!
By imkaren4u
April 29, 2016
Great value
I use Zymox Otic on my shih tzu's ears. It doesn't cause her any pain or irritation. I used the kind with hydrocortizone in it. She was having an issue and would shake her head and the Zymox cleared them up.
By Bobi
March 28, 2016
Helps a Little
Keeps the smell and the itching down but doesnt seen to ever actually cure the problem.
By kate
February 9, 2016
Itchy Ear Help
Our one dog has itchy ears -- no medical issues. Our Vet recommended this Zymox Otic once or twice a week and it keeps her itchy free.
By Nancy62
New Jersey
February 2, 2016
Exceptional product
Product works great, it's wonderful because it works without having to clean the ears
By Debbie
January 18, 2016
Such a great product!
Our German shepherd has experienced terrible allergy problems in addition to chronic ear problems. After many vet visits, I researched and found this product. I figured I had nothing to lose by trying it. Well it has made an incredible difference. His ears are no longer inflamed, flakey or weepy. And they look nice and pink like the inner ear should look. He no longer shakes his head from the constant irritation. Upon a return visit to the vet, this product was discussed with him. He, in fact, stated that he was going to start prescribing it as he had read it was one of the best treatments on the market. I would highly recommend it for any dog that has chronic ear problems. It has made a world of difference!
By Sierramom
Lake Worth, FL
December 25, 2015
Best Ear Treatment Ever!!
Fantastic Product and the only one I trust to rid my dog of yeast infections in her ear. I have used this product after other ear cleaners and treatments have failed. My dog had an aural hemotoma and I used this to make sure she would not get one again.
September 19, 2015
my pup's ears are clean! we got this stuff from the vet before, so nice to get it conveniently online.
By slcgal
August 28, 2015
Really worked
My Tibetan Spaniel got a yeast infection in her ears and was scratching, itching, and miserable. This cleared it up in just a couple of days.

Questions and Answers

1 Question & 0 Answers
from Fruitland Park, FL asked:
February 26, 2015
Used on cat but he cleaned excess off side of ear and then licked his paw. Will the hydrocortizone in it hurt him or make him sick? Thanks

3-PACK Zymox Ear Cleanser (12 oz)3-PACK Zymox Ear Cleanser (12 oz)Reg price: $46.99
Sale price: $35.97
6-PACK Zymox Ear Cleanser (24 oz)6-PACK Zymox Ear Cleanser (24 oz)Reg price: $93.99
Sale price: $71.94
3 PACK Zymox Otic (1.25oz) with Hydrocortisone (1.0%)3 PACK Zymox Otic (1.25oz) with Hydrocortisone (1.0%)Reg price: $85.99
Sale price: $65.97
Zymox Otic w/ Hydrocortisone 1.0% (4 oz)Zymox Otic w/ Hydrocortisone 1.0% (4 oz)Reg price: $67.99
Sale price: $51.99
CALL IN YOUR ORDER 800.889.8967

Stay in touch. Friends fur-ever!

Terms and Conditions

You have to agree on terms in order to proceed to the subscription.