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12 MONTH Advantage II Flea Control for Extra Large Dogs (Over 55 lbs) Video

12 MONTH Advantage II Flea Control for Extra Large Dogs (Over 55 lbs)

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The new and improved Advantage II now offers flea and lice protection for your dog. Flea and lice treatment with Advantage II gives your dog a safe solution that only needs to be applied once a month. Dogs and puppies older than 7 weeks and weighing over 55 lbs are fit for this flea and lice killing formula.


Advantage II Flea Treatment for Extra Large Dogs. This highly-effective, veterinarian-recommended treatment is specifically formulated to kill all life stages of fleas on contact with no painful biting required. With three-way protection that kills the eggs, larvae and adults, it breaks the flea life-cycle to help prevent re-infestation of both your house and hound. The waterproof formula for dogs 7 weeks or older and weighing over 55 pounds continues working for up to four weeks, even after bathing or swimming.

  • Veterinarian-recommended treatment kills all life stages of fleas on puppies and dogs 7 weeks or older and weighing over 55 pounds.
  • Begins working within 12 hours to kill fleas on contact.
  • Kills eggs, larvae and adult fleas to break the life cycle and help prevent re-infestation.
  • Waterproof formula continues working for up to four weeks, even after bathing or swimming.
  • Convenient, monthly topical application contains imidacloprid and pyriproxyfen; available in packs of 4 or 6 treatments.


Active Ingredients by Weight
Imidacloprid 9.10%
Pyriproxyfen 0.46%
Other Ingredients 90.44%
Total 100.00%

Useful Information

Advantage II Flea Control for Dogs

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

    How To Open:

  • Be sure tube is at bottom of pouch.
  • Using scissors, cut the pouch across the top and remove tube.

    How to Apply

  • Remove one applicator tube from the package. See "HOW TO OPEN" section
  • Hold application tube in an upright position facing away from you and your pet's face and eyes. Pull cap of tube.

  • Turn the cap around and place other end of cap back on tube.
  • Twist cap to break seal, then remove cap from tube.
  • The dog should be standing for easy application. Part the hair on the dog's back, between the shoulder blades, until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. Do not get this product in your pet's eyes or mouth.

  • Discard empty tube as described in Storage and Disposal.
  • Under normal conditions this product is effective for a month. However, in cases of severe flea infestation, re-treatment may be necessary earlier than four (4) weeks. Do not retreat more often than once every seven (7) days. After flea control is obtained, return to a monthly re-treatment schedule.


  • Use only on dogs. Do not use on other animals.
  • Do not apply more than one (1) tube per treatment, even for larger dogs.
  • Do not have contact or allow children to have contact with treated area until completely dry.

CAUTIONS: Harmful if swallowed. Causes moderate eye irritation. Avoid contact with eyes or clothing. Wash hands thoroughly with soap and warm water handling. Keep out of reach of children. Do not contaminate feed or food.


For external use only. Do not use on puppies under seven weeks of age. As with any product, consult your veterinarian before using this product on debilitated, aged, pregnant or nursing animals. Individual sensitivities, while rare, may occur after using ANY pesticide products for pets. If signs persist, or become more severe, consult a veterinarian immediately. If your animal is on medication, consult your veterinarian before using this or any other product.

Customer Reviews

27 Reviews
78% (21)
11% (3)
0% (0)
4% (1)
7% (2)
89% Recommend this product (24 of 27 responses)
By Patti
March 28, 2016
Reallllllly works
Do not live with pets that have fleas! Life is so much better for all without fleas.
By Mes P.
October 6, 2014
Fleas war, I win
Best product I have bought for fleas and ticks. really satisfied
July 28, 2014
No more fleas!
We have FOUR 55+ pound dogs. The Advantage II Flea Control has been the best product to kill & control flea infestation. Coupled with the yard spray, we have totally eliminated all the fleas!! We have tried other products, but to no avail. This product is 5 stars! Don't waste your money on other products.
By lynnelab
July 11, 2014
great value
Great flea control and easy to apply. Much cheaper buying from EntirelyPets rather than from vet's office.
By Bobbie
June 20, 2014
Prompt service by entirely pets
The product doesn't inform you of the amount of the liquid in each tube. I wish they did.
By Roxxy
Graham, WA.
May 14, 2014
Always a Great Choice !!!
Works very well on both my Large dogs...one is 85# and the other is 130#......No Fleas......
By Dan
November 29, 2013
To your door.
We have always used Advantage II since the vet introduced us to it. But ordering it online was easy, and no expensive trip to the vet to end up bringing home the same product. Not to mention that it is a fraction of the price that the vet charges for the exact same flea control.
By catlady
townsend, de
November 5, 2013
advantage ll
Best product and cheap. Entirely Pets delivery is fast and safe.
By Jungle J.
October 8, 2013
Best on the market!!
I am soooo tired of throwing away my hard earned money on flea products that DON'T WORK! Advantage 2 works for me and I actually get a whole month's worth of protection.
My dogs walk around with a smile on their face
instead of a frown now. They can actually walk on 4 feet instead of trying to itch at the little pest every few steps. Thanks !! Advantage 2 !!!
By phil
September 30, 2013
Works Great
Advantage is one of the best products on the market. I noticed a difference within a few hours. It didn't bother my dog at all and we've not had any flea issues since using it. I'm really impressed with the quality and price.
By Eli M.
September 22, 2013
Best product
If you only have a problem with fleas this is the best product to use on your four legged family members. It is easy to use and you don't have to try to trick your pet into taking a pill to get rid of them. I will always continue to use Advantage.
By EliMae
August 30, 2013
Advantage II
This is a great product for cats & dogs for flea control! The only downside is it doesn't help with ticks. I use it for 10 shop cats, 9 home cats & 2 dogs...NO Fleas!!
By kate
Fort Worth ,Texas
July 5, 2013
12 month advantage II Flea Control
Great product and Great price. My boys remain flea free
By Deb
Pensacola, FL
June 9, 2013
Best flea protection
I have three dogs and a cat in Florida! Fleas can be a problem but NOT when I use Advantage II on all of them regularly.
We are "Flea Free" thank you!
By sampson l.
April 16, 2013
thank you
great prices, great shipping time
Thank you!
By Hilary
March 24, 2013
Advantage II is a great product.
I never have any flea trouble when using Advantage II, and Entirely Pets always has the best price. The package always arrives quickly, too.
By milos
February 19, 2013
best value
I have priced Advantage on many sites and with many vets, this is by far the best priced and fast fuss free shipping. I have 4 large dogs and it's great to get the best working products for this price and delivered to the door.
By catlady
Enid, OK
February 19, 2013
great for treating both cats and dogs
My vet told me how to save money by buying this large size to use both on my cats and dogs. This has saved me a lot of money and the advantage II is great product.
By Texas J.
West Texas
October 25, 2012
Never a sign of a flea or a tick
Max was 2 when we adopted him. It has been 6 years and we have used nothing but Advantage and then Andvantage II when it came out. Never have seen a sign of a flea or a tick. Can't do better than that!
By Lsodea
October 23, 2012
Does not seem to work
I put this on my dogs a week ago and they are scratching fleas again. I bought the same product several months ago from petsmart (I did not realize that I was out so had to purchase it at petsmart -- much more expensive) and it seemed to kill the fleas for quite some time -- it seemed to work correctly.

I don't know if the product from Entirely Pets is old or something, but it is not working as well as the stuff that I bought from PetSmart.
By I n.
July 18, 2012
Good service, product no longer works
Love the service of entirely pets. Sadly, this product, Advantage, just doesn't seem effective against the fleas in Central Florida any longer.

At least it isn't working for us.
By mytwocents
July 5, 2012
Great product; great price
I always buy my Advantage from Entirely Pets. They have the best price and this stuff really works. I bought some for my daughter, who was having a huge flea problem and within hours of applying on her five dogs and treating the carpet, there was a noticeable difference and the fleas have not returned.
By catlady
townsend, delaware
July 5, 2012
safiest product on the market. Its all I ever use. I do alot of rescue for animals and I can trust it to work.
By RTPLady
May 29, 2012
Review for 12 MONTH Advantage II Flea Control for Extra Large Dogs (Over 55 lbs)
This is a Good product. I've used it before and will use it again
By Sarah
Los Angeles, CA
May 29, 2012
Advantage has stopped working
We bought the 12 month supply of advantage II and it seems to no longer be effective. We put it on our puppy, who is allergic to fleas, and less than two weeks later she had fleas again. I don't know if the formula has changed or the fleas are now resistant but it's not doing anything for my poor itchy girl.
By nonick
March 19, 2012
Review for 12 MONTH Advantage II Flea Control for Extra Large Dogs (Over 55 lbs)
Convinient, helpful, works as expected, reasonable price.
By 5badkatz
Orlando Florida
February 6, 2012
Product really works without making pets sick or smell funny. I hate fleas. Can't imagine life without this any more.

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