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  6. 6 MONTH Advantage II Flea Control for Large Dogs (21-55 lbs)

6 MONTH Advantage II Flea Control for Large Dogs (21-55 lbs) Video

6 MONTH Advantage II Flea Control for Large Dogs (21-55 lbs)

Item: 5461766
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Advantage II Flea Treatment for Large Dogs. This highly-effective, veterinarian-recommended treatment is specifically formulated to kill all life stages of fleas on contact with no painful biting required. With three-way protection that kills the eggs, larvae and adults, it breaks the flea life-cycle to help prevent re-infestation of both your house and hound. The waterproof formula for dogs 7 weeks or older and weighing 21-55 pounds continues working for up to four weeks, even after bathing or swimming.

  • Veterinarian-recommended treatment kills all life stages of fleas on puppies and dogs 7 weeks or older and weighing 21-55 pounds.
  • Begins working within 12 hours to kill fleas on contact.
  • Kills eggs, larvae and adult fleas to break the life cycle and help prevent re-infestation.
  • Waterproof formula continues working for up to four weeks, even after bathing or swimming.
  • Convenient, monthly topical application contains imidacloprid and pyriproxyfen; available in packs of 4 or 6 treatments.


Active Ingredients by Weight
Imidacloprid 9.10%
Pyriproxyfen 0.46%
Other Ingredients 90.44%
Total 100.00%

Useful Information

Advantage II Flea Control for Dogs

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

    How To Open:

  • Be sure tube is at bottom of pouch.
  • Using scissors, cut the pouch across the top and remove tube.

    How to Apply

  • Remove one applicator tube from the package. See "HOW TO OPEN" section
  • Hold application tube in an upright position facing away from you and your pet's face and eyes. Pull cap of tube.

  • Turn the cap around and place other end of cap back on tube.
  • Twist cap to break seal, then remove cap from tube.
  • The dog should be standing for easy application. Part the hair on the dog's back, between the shoulder blades, until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. Do not get this product in your pet's eyes or mouth.

  • Discard empty tube as described in Storage and Disposal.
  • Under normal conditions this product is effective for a month. However, in cases of severe flea infestation, re-treatment may be necessary earlier than four (4) weeks. Do not retreat more often than once every seven (7) days. After flea control is obtained, return to a monthly re-treatment schedule.


  • Use only on dogs. Do not use on other animals.
  • Do not apply more than one (1) tube per treatment, even for larger dogs.
  • Do not have contact or allow children to have contact with treated area until completely dry.

CAUTIONS: Harmful if swallowed. Causes moderate eye irritation. Avoid contact with eyes or clothing. Wash hands thoroughly with soap and warm water handling. Keep out of reach of children. Do not contaminate feed or food.


For external use only. Do not use on puppies under seven weeks of age. As with any product, consult your veterinarian before using this product on debilitated, aged, pregnant or nursing animals. Individual sensitivities, while rare, may occur after using ANY pesticide products for pets. If signs persist, or become more severe, consult a veterinarian immediately. If your animal is on medication, consult your veterinarian before using this or any other product.

Customer Reviews

20 Reviews
90% (18)
5% (1)
0% (0)
5% (1)
0% (0)
95% Recommend this product (19 of 20 responses)
By JimInPA
Camp Hill, PA
February 20, 2015
Very effective flea control
We had been using Frontline but last year, it was not doing the job, so we switched to Advantage II and the fleas are losing. Hopefully they won't build up an immunity to this product.
By alice
August 6, 2014
Best control for fleas
this product works very well,all my animals are on the advantage ll products . And we are flea free .
By Karen
September 29, 2013
Review for 6 MONTH Advantage II Flea Control for Large Dogs (21-55 lbs)
I will not purchase it again as it does not control ticks
By mooca
Blacks Harbour, NB. Canada
July 13, 2013
Great buy!
Was able to upgrade to Advantage II for all 5 pets, for 6 mos. Much better buy than from local vet. Shipping fast and efficient, even though it had to cross the country, and was free besides, yay! Will buy from Entirely pets again and tell my friends!
By librarydogmom
La Mesa, California
July 8, 2013
Good product
Works fine. I also use it on the cat, putting one vial into a small container and, with a syringe, taking .8 mg for him. One vial of the dog Advantage is at least 4 treatments for the cat.
By rich
June 4, 2013
Excellent product.
Great buy. Excellent product. It's important to protect your dog's health.
By woman
Winston-Salem, NC
February 6, 2013
Advantage II Flea Control for large dog 21-55 lbs
Great and easy to use - always use this for my dog as she has skin problems and it does not cause her to have problems
By puglover
January 8, 2013
Advantage Flea & Tick
Great Product.....Use it all the time....
By Missy
Tulsa, OK
December 28, 2012
Love this flea product!
I have shopped around and used many different flea products, cheap and expensive, but none have compared to Advantage. It kills the fleas instantly on my dogs--dachsund mixes--and is gentle on them. My dachsund/terrier mix has had skin irritations with many brands, but he has no problem whatsoever with Advantage. We LOVE it!!!
By Mikie
Manhattan Beach, CA
November 27, 2012
Avantage 11
Great product. In 10 years Meggie has never had a flea
By Barbara
November 26, 2012
At Last No Fleas!
The product came earlier than expected. Used it right away on my two dogs. 24 hours later there were no fleas on either dog. At last they had relief from the itching of the flea infestation. Needless to say I am very happy with the product.
By Kim
Quakertown, PA
November 14, 2012
Great Product at a Great Price
I have never had an issue with the Advantage products; you hear about Frontline no longer working and people winding up with fleas in their homes; that has not happened with Advantage and I have been using it for years. I would highly recommend this product.
By bogiemike
Portland, OR
November 13, 2012
easy to use
advantage II keeps our pets flea free. It works as stated and is easy to use on all our pets.
By Icabode
Birmingham, AL
November 7, 2012
Works Great
Works much better than any other brand I have used
By jk
October 28, 2012
excellent product at a good price
I had used frontline for years...after moving to florida it did not seem to work anymore. After doing some research I decided to give advantage II a try...wow what a life saver....my dogs were no longer being tormented by fleas. You can not beat the price from entirely pets or the fast shipping and excellent customer service....no worries here...
By iLoveMyPets
October 26, 2012
Great product
Just started using this on our 4 month old Aussi and it works great... We think he had some flees, but after one dose and a couple days no trace.
By jeanief24
July 11, 2012
Love this product
Great stuff and it reallly keeps the fleas and ticks away
By Jasmine's M.
Dallas, TX
June 15, 2012
Great Product!
I have never had any problems with fleas while using this product. My furry child has never had any adverse reactions. She's had seizures in the past, so I am very particular about the products I use.
By patthemiddlechild
December 12, 2011
Always reliable
It is a crime all pet owners don't use
flea treatment.

there is no excuse for fleas any longer!!
By Boxer
November 29, 2011
Works good
Have used this product in the past, as well as frontline. This product works much better!

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