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  6. Advantage II Small Dogs 3-10 lbs.|Vet-Recommended Flea Treatment & Prevention|6-Month Supply

Advantage II Small Dogs 3-10 lbs.|Vet-Recommended Flea Treatment & Prevention|6-Month Supply Video

Advantage II Small Dogs 3-10 lbs.|Vet-Recommended Flea Treatment & Prevention|6-Month Supply

Item: 5461715
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Deliver total flea protection to your dog or puppy with Advantage II Small Dog. This vet-recommended, topical treatment and prevention formula kills adult fleas, flea larvae, and flea eggs on contact within 12 hours of application - meaning fleas can be eliminated before they bite or lay new eggs. Effectively break the flea life cycle, control existing flea and lice infestations, and prevent further infestations with one simple application. Advantage II Small Dog flea and lice protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh 3-10 lbs. to use Advantage II Small Dog.

Advantage II Small Dog is a trademark of Elanco or its affiliates.

Key Benefits:

  • Vet recommended flea treatment and prevention for dogs at weighing 3 to 10 lbs., at least 7 weeks of age
  • Kills adult fleas, flea larvae and flea eggs for total flea prevention and treatment
  • Same-day effectiveness, kills fleas within 12 hours of application and keeps working for 30 days
  • Easy-to-apply topical treatment, no prescription needed
  • Fragrance-free formula, waterproof after 24 hours


Active Ingredients by Weight
Imidacloprid 9.10%
Pyriproxyfen 0.46%
Other Ingredients 90.44%
Total 100.00%

Useful Information

Advantage II Flea Control for Dogs

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

    How To Open:

  • Be sure tube is at bottom of pouch.
  • Using scissors, cut the pouch across the top and remove tube.

    How to Apply

  • Remove one applicator tube from the package. See "HOW TO OPEN" section
  • Hold application tube in an upright position facing away from you and your pet's face and eyes. Pull cap of tube.

  • Turn the cap around and place other end of cap back on tube.
  • Twist cap to break seal, then remove cap from tube.
  • The dog should be standing for easy application. Part the hair on the dog's back, between the shoulder blades, until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. Do not get this product in your pet's eyes or mouth.

  • Discard empty tube as described in Storage and Disposal.
  • Under normal conditions this product is effective for a month. However, in cases of severe flea infestation, re-treatment may be necessary earlier than four (4) weeks. Do not retreat more often than once every seven (7) days. After flea control is obtained, return to a monthly re-treatment schedule.


  • Use only on dogs. Do not use on other animals.
  • Do not apply more than one (1) tube per treatment, even for larger dogs.
  • Do not have contact or allow children to have contact with treated area until completely dry.

CAUTIONS: Harmful if swallowed. Causes moderate eye irritation. Avoid contact with eyes or clothing. Wash hands thoroughly with soap and warm water handling. Keep out of reach of children. Do not contaminate feed or food.


For external use only. Do not use on puppies under seven weeks of age. As with any product, consult your veterinarian before using this product on debilitated, aged, pregnant or nursing animals. Individual sensitivities, while rare, may occur after using ANY pesticide products for pets. If signs persist, or become more severe, consult a veterinarian immediately. If your animal is on medication, consult your veterinarian before using this or any other product.

Customer Reviews

Review Summary
244 Reviews
79% (193)
14% (34)
1% (3)
2% (5)
4% (9)
94% Recommend this product (229 of 244 responses)
By Passion P.
Works well and great price!
November 22, 2021
I have used this for years. Having many dogs, I need something that works for sure and at a decent price. Transaction and shipping always smooth. Have bought from them for years.

Merchant Response:Wonderful Passion! Glad to have you and your beautiful dogs as customers.
  • Works even when dog gets wet. Just dont dry ur dog w a towel vigorously, obviously. With a basic dry off, Advantage keeps working. Dogs are always comfortable
  • None
By Dee n.
Marion Illinois
Advantage II for large dogs
October 19, 2021
This product works great for my Golden Retriever she never has a flea on her and my backyard is surrounded by a forest. She also like to roll around in the grass and without Advantage I’m sure she would have plenty of fleas!
  • Easy to apply and doesn?t matter if she hAs a bath or goes swimming.
  • I haven?t had a single problem with this product!
By Shirley H.
Advantage II
May 11, 2021
I use this on my 75 pound Pit Bull and it's very easy to use. Keeps her scratch free.
By Erin R.
Chatham NY
So far so good!
November 9, 2020
We are happy so far seems to be working.
By Diane
Southern Illinois
Advantage II
November 6, 2020
Best control of FLEAS ever. My 2 dogs never have a problem and I recommend this product.
By Deborah
Lakewood, NY
Great Product
October 27, 2020
We use this every month and never see any fleas!
  • No fleas
  • Not the best smell
By Leigh
No fleas!
April 29, 2020
We have been using Advantage II on our dogs for years, It works great. No fleas! Happy dogs! Happy us!

Merchant Response:Flea-free is the way to be!
By patricia
oshawa, ON
works will
April 28, 2020
works will. keeps them off
By Patricia
oshawa, ON
works will
April 28, 2020
works keeps them off
By Pixie
Sacramento, CA
Advantage II flea cotrol for dogs
June 28, 2019
Kills the fleas
By Roxie
Sacramento, CA
great product
June 28, 2019
Does the job to kill fleas
By Dog l.
Review for 6 MONTH Advantage II Flea Control for Extra Large Dogs (Over 55 lbs)
January 24, 2019
This works so well on my dogs! My dogs cannot use Nexguard due to seizures and this is the next best thing.
  • Works well
  • Put on their backs monthly
By Amanda101
Doesn't work
November 23, 2018
I bought this because my dog refuses to eat comfortis any longer and this medicine does not work ! Do not spend over $100 on this scam. Waste of money I can't even return product and does not work dog still has fleas even though I applied as shown to dog and this was 4 weeks ago. Do not buy !
  • Doesn't work
By Alaska808
Works for me
September 24, 2017
Use it on a regular basis. No adverse reactions or problems with this product.
By Mikie
Southern California
flea control for my dog
July 13, 2017
My dog ,Meg, is 14 y/o and with this product has never had fleas. I get the product within days of ordering online at a good price.
Thank you Entirely Pets
By Bella2012
Peterborough, Ontario
One dose and fleas were gone
October 24, 2016
I only used it once and my dog was fine, still has not had any fleas
By Susan
great luck with this product working
August 2, 2016
reasonably priced if you want to use a topical product for fleas
By Nanna
Bokoshe, Oklahoma
Works really well
May 28, 2016
We have 5 "Chiwenies" . We live in the country, and fleas and ticks are a problem, even when we treat the yard. This product is really great. We use it on our cats too'
Don't like the spray product much. A fight to apply, and doesn't work as well.
By Joseph
San Augustine, Texas
Flea Meds
March 30, 2016
The shipping was very fast and the product seems to work.
By Patti
Reallllllly works
March 28, 2016
Do not live with pets that have fleas! Life is so much better for all without fleas.
By michelle
very good product
January 20, 2016
Advantage II works great. Not a flea on the dogs since I started to use it, many years ago. Thank you.
Cedar Falls, Iowa
Great purchase
January 10, 2016
I rely on this product to keep my pet safe.
By jimfyd
Albuquerque, NM
Advantage II
December 19, 2015
I'v used before with satisfactory results.
By Floydieboy
Abbotsford, BC
Great Stuff!
October 26, 2015
This product is great - I use it on my Cane Corso as a precautionary as he attends doggy daycare and although he has never had fleas, this product will ensure that he never does!
October 2, 2015
- This is the only brand I've ever used on my dog since he was a puppy. He's 9 years old now and never had a problem when he was on it. One time after coming back from a friend's house (I'd forgotten to put Advantage on him), I noticed he had tons of fleas, quickly gave him a thorough bath, and put the medication on him. Fleas went away within a few days. Would definitely keep using this brand and honestly don't think I'll switch anytime soon.
- Also, my dog is usually around 10-11 lbs. I use the "dogs under 10 lbs Advantage" because that's what my vets gave me.
By Kelly
Austin, TX
Great Deal!
September 22, 2015
This product works well. I've used it for a long time. This is by far the best deal I've found on it. Shipping was very fast as well.
By Abitabb
Advantage II - Safe Efficient Product
July 9, 2015
I've used Advantage II since it came out for my dogs and occasionally my cats (indoor so rarely need flea control). It's safe, acts swiftly to control any biting bugs on the dogs and is safe for use around cats (not everything is!).
By lostmule
Don't work any more
June 9, 2015
Although they have helped in the past the Advantage products seem to have little effect on fleas now so will be searching for some other product that will work.
By sjpop
Best Protection
May 13, 2015
I live in a rural PA where fleas, ticks and other biting insects are rampant. Advantix II provides the best protection for my dogs. I have tried a variety of products but none provided complete protection for the full 30 days. The best perk was saving $35 by purchasing Advantix II through Entirely Pets rather than my vet or pet store .
By IsabellaRuby
Los Angeles, CA
Great Purchase
May 12, 2015
On my Golden 9 yrs-no fleas and no fear of them

Questions and Answers