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  6. 3 PACK Denosyl for dogs over 25 lbs (90 tablets) 225 mg

  • DENO2253PKDENO2253PK
  • DENO2253PKDENO2253PK

3 PACK Denosyl for dogs over 25 lbs (90 tablets) 225 mg

Item: DENO225PK3
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Denosyl is a nutritional supplement that helps minimize a variety of liver problems in dogs. It has also been shown to improve liver health and function by protecting and repairing liver cells. It is recommended to improve hepatic glutathione levels in dogs and cats. For optimal absorption, give your dog or cat Denosyl on an empty stomach, at least an hour before feeding.

Denosyl, a nutritional supplement, is the pure and stabilized salt of S-Adenosylmethionine for veterinary use only. It is the only brand researched in medical trials for veterinary use in dogs.

S-Adenosylmethionine is an endogenous molecule synthesized by cells throughout the body and is formed from the amino acid methionine and ATP. It is an essential part of three major chemical pathways in the body.

Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidant that protect hepatic (liver) cells from toxins. A study found that low liver glutathione concentrations are common in dog and cats with decreased liver function.

For optimal absorption, tablets should be given on an empty stomach, at least 1 hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulties administering tablets to their pets, this medication may be disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach in cats, but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the tablet into the stomach. Denosyl 9- mg tablets are ideal for cats because of their small size.



Useful Information

Body Weight Total Daily Administration & Tablet Size
Up to 12 pounds (5.5 kg) One tablet of 90 mg
13 to 34 pounds (6-15.5 kg) One tablet of 225mg
35 to 65 pounds (16 to 29.5 kg) One tablet of 425 mg
66 to 120 pounds (30 to 54.5 kg) Two tablets of 425 mg
Over 120 pounds (54.5 kg +) Three tablets of 425 mg

The number of tablets can be gradually reduced or may be increased at any time depending on the pet's needs.

Storage: Store in a cool, dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.

What does the liver do? The liver participates in many activities within the body. It helps the digestion of food through production of bile and helps change digested foods into substances used by the body for energy and growth. The liver also helps process some medications into material(s) that can be used by the body; the liver may assist in eliminating medications from the body once they have had their effect. The liver stores vitamins and minerals and works with sugar (carbohydrates, glucose), fats and proteins. It also helps maintain proper blood clotting and removes many body toxins from the blood. Without proper liver function, the pet's health is compromised.

Because it does so much, the liver may be subject to many things: injury, both direct and indirect, infection, and toxicity. Some of the signs and symptoms of compromised liver function in pets may include: weakness, vomiting, poor appetite, and/or seizures. But if there is mild or early stage liver compromise, the pet can appear normal. If you notice any of these symptoms or your pet is just acting differently, you should contact your veterinarian. Many veterinarians run screening tests for middle aged and older patients during the annual examination to ensure that organ function is normal.

Customer Reviews

40 Reviews
75% (30)
23% (9)
3% (1)
0% (0)
0% (0)
98% Recommend this product (39 of 40 responses)
By Pointer M.
NE Ohio
March 4, 2016
Great value
My 13 yr old male GSP is on Denosyl for his liver, and so far he's doing great on it. I like that I can buy a value pack since he takes 2 tablets/day.
By Rivers R.
November 2, 2015
Excellent product!
Libby is an 11 yr old rescue.

Thanks to Denosyl her liver values are up to where they should be and it gives us peace of mind that the supplementation is aiding her liver function!
By Winnie
March 24, 2015
Liver support
This supplement seems to have helped my 15 year old dog. Her numbers were improved at her last check up.
By pj
October 16, 2013
My vet recommended Denosyl
My dog has Cushings disease and this is supposed to help aid her liver function. I can't really tell how well it works. She's been on it for 5 years. I only buy it at Entirely Pets, though I search the web for deal every few months. Entirely Pets always has the best price to be found for Denosyl.
By Hope
September 17, 2013
Great product at an even better price! Thanks
By June
Upstate New York
August 27, 2013
Worked wonder
Denosyl, prescribed by my vet, is an excellent product. I buy fromEntirely Pets because of the low price offered and am very happy with their company.
By TerryL
North East Alabama
July 1, 2013
Better Buy
I was so relieved to find Denosyl at a better price. My Welsh Cardigan Corgi has liver disease and needs this product daily. I ordered the exact same product that I was getting at my vet's but at nearly a 50% savings. Since I recently lost my job, finding Denosyl at was a big relief.
By LikesArt
July 1, 2013
Seems to be helping
My rat terrier has been on this for several years (vet recommended) for liver support and it seems to be keeping her stable.
By TaraTriniti
Lafayette La
June 21, 2013
Saved my dogs life
I could not have asked for a better product!!!!!!
By malbee1023
Batavia, NY
May 13, 2013
Denosyl for dogs
I saved literally $20 per box by ordering here rather than getting it through the vet.
It arrived 2 days after I placed my order, pretty fast.
The blood work on my dog since taking it has improved.
By jamie
New Jersey
April 30, 2013
Does what's needed
I've used this product for several years since my dog was diagnosed with "some liver problems". Apparently, it's working because Jamie no longer is at risk for liver disease. It's a supplement and doesn't seem to have any adverse affect. Worth a try!
By Murph
April 5, 2013
Review for 3 PACK Denosyl for dogs over 25 lbs (90 tablets) 225 mg
The cost is lowest I have seen and I received the medication in a very timely manner.
By IfNotForSitsWhyWarm
Lexington, KY
April 1, 2013
Best price for these meds
This was prescribed by our vet for our older cocker spaniel. She takes it every day, so I have had to find the best price to make the cost hit lower. I assume it works as expected since our vet continues to prescribe it.
By Nan
March 24, 2013
Seems to help.
My Miniature Schnauzer was suffering from multiple seizures a day. Since starting her on Denosyl she has not experienced any seizures.It might be coincidence, but If its not the Densoyl "helping", it's not hurting either.
By Ro
March 7, 2013
Review for 3 PACK Denosyl for dogs over 25 lbs (90 tablets) 225 mg
This product is wonderful...I have used it for my pet Polo for nine years....sadly I just lost him at 14 to his liver issues...but this procuct did help over the years to rebuild his liver function
By Sandi R.
February 19, 2013
My sheltie went from complete liver failure to normal liver function in less than two weeks. She was on hepatic health dog food and took a denosyl every night. The vet said it was a miracle and couldn't believe her health change. She is back to normal food but still takes the denosyl. It's a small price to see her happy face when I get home!
By mrsclean
February 9, 2013
Great price...
I have not found a better price or better service. Very happy I found EntirelyPets.
By JoeB
Vancouver, WA
February 5, 2013
Excellent product!
This is a great product. Adds years to the life of your dog.
By nae
November 12, 2012
great deal
This product has worked great for our dog has proably saved her life.
By Rose
November 5, 2012
Great Purchase
I purchased this product at a great price & deliverly was awesome. Will definitely purchase again.
By sandy
Westchester NY
October 23, 2012
Product is fantastic. Has maintained my dog's liver in a reasonalbly healthy state. She is on Phenobarbital which can distroy the liver. Have used denosyl for 5 years. My dog is now 15 yrs. old and going strong.
By Fran
Brookfield, MA
August 21, 2012
Best Purchase Ever
This product is great. I find the ordering process the best and most efficient, reliable and dependable. That is what I needed and that is what I received. Customer Service is outstanding.
By Savanna
Waterford, Mi.
July 28, 2012
Excellent value
I love the option of buying a three pack. I have two dogs who take the same dose so one pack only lasts me fifteen days. With the three pack it's convenient and economical. I wish the product would be offered in chewables three pack as the dogs don't like the taste so I put them in Pill Pockets.
By Mel
June 19, 2012
Review for 3 PACK Denosyl for dogs over 25 lbs (90 tablets) 225 mg
Product is ok. But we were supposed to purchase the CHEWABLE form.
By KitS
Tucson, AZ
June 12, 2012
Helps protect liver
Our beagle has epilepsy and takes phenobarbital. The denosyl was recommended by our vet to protect his liver several years ago. He is now 17 and doing quite well.
By Soosie
June 9, 2012
Good price for a 3 pack
Good service and prices. My dog takes Denosyl all the time so it was important to find a reasonable source for me to purchase on a regular basis. Thanks for being there.
By frang
Virginia Beach,VA.
June 5, 2012
denosyl for dogs
great price, fast of both worlds.
By Roses1
May 30, 2012
For Health's Sake
My senior aged dog has had elevated liver enzymes for the past few years. With Denosyl the health of her liver has stabilized. Great product.
By Baldwin's M.
April 1, 2012
Great Value
My Boston Terrier must take Denosyl, probably for the rest of his life. Entirely Pets saves me a bundle. I love my vet, but medication prices are ridiculous. I like having this product shipped right to our home, at a fair price. Thanks.
By kit1308
Tucson, AZ
March 17, 2012
liver support
Our elderly dog is on phenobarbitol for seizures. These provide liver support for him and keep his numbers close to the normal zone.

Questions and Answers

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3 Pack Denosyl for small dogs and cats (90 tablets) 90 mg3 Pack Denosyl for small dogs and cats (90 tablets) 90 mgReg price: $81.99
Sale price: $62.97
Denosyl for dogs over 25 lbs (30 tablets) 225 mgDenosyl for dogs over 25 lbs (30 tablets) 225 mgReg price: $36.99
Sale price: $27.99
Denosyl for dogs over 35 lbs (30 tablets) 425 mgDenosyl for dogs over 35 lbs (30 tablets) 425 mgReg price: $63.99
Sale price: $48.99
3 Pack Denosyl for dogs over 35 lbs (90 tablets) 425 mg3 Pack Denosyl for dogs over 35 lbs (90 tablets) 425 mgReg price: $191.99
Sale price: $146.97
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