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12 MONTH K9 Advantix II BLUE for Extra Large Dogs (over 55 lbs) Video

12 MONTH K9 Advantix II BLUE for Extra Large Dogs (over 55 lbs)

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Keep your dog safe from irritating and dangerous pests with K9 Advantix II for Extra Large Dogs weighing over 55 pounds. Formulated for dogs seven weeks of age and older and weighing over 55 pounds , K9 Advantix II outperforms its competitors not only by killing more varieties of pests, but also by repelling them to prevent future attacks.


K9 Advantix II is one of the top choices for eliminating the resident tick or flea population. It is manufactured by Bayer, one of the leading pet care companies in the world. This product promises to kill and repel ticks, fleas, and mosquitos. Its waterproof formulation remains effective even after the pet gets wet. The K9 Advantix II solution works by attacking all the life stages of the parasites killing adult bugs, larvae, and eggs. The K9 Advantix II Green is a specialized product for dogs weighing over 55 lbs.

  • For large dogs weighing over 55 lbs
  • Manufactured by Bayer
  • Waterproof formulation
  • Repels ticks, fleas and mosquitoes
  • Kill parasites of all life stages
  • For dogs only
  • Ingredients

    Imidacloprid is an ectoparasiticide, an antiparasitic agent that targets parasites living primarily on the surface of a host. Chemically classified as a chloronicotinyl nitroguanidine, imidacloprid inhibits neurotransmitter transmission in insects, resulting in paralysis and death.

    Imidacloprid exhibits both adulticide and larvicidal flea efficacy; it not only kills adult fleas and larvae on your pet, but it also kills larval stages in your pet's immediate surroundings.

    Main Purpose
    To kill fleas at all stages of their life cycles and stop them from being able to move or feed.

    Permethrin is the additional ingredient in Advantix. It belongs to the Type I class of pyrethroid acaricides and insecticides, and it also acts as a repellent. Pyrethroids affect muscle and nerve cells' sodium ion channels by increasing their mean open time, which leads to hyperexcitability and death of the parasite.

    Thanks to its repelling activity, permethrin reduces parasite bites and thus the risk of diseases and stress for your dog.

    Main Purpose
    To repel ticks, sand flies, and mosquitoes; to kill ticks and fleas.

    Two Proven Ingredients with Enhanced Activity
    Imidacloprid and permethrin work together to overwhelm the nervous system of the parasite, providing neurotoxic activity beyond that of each compound alone. This leads to more profound and quicker insect paralysis and death.

    Specifically, imidacloprid increases the efficacy of permethrin by activating insect nerve cells and increasing the frequency of neurotransmissions. As a result, more sodium channels are opened and the pyrethroid can interact much better with its target site.

    Pyriproxyfen is a pyridine-based pesticide. A juvenile hormone analog, it interferes with the hormone signaling of growing insects, so that insects in immature stages are unable to mature. Additionally, a female insect that touches the toxin will produce eggs that will not hatch.

    Pyriproxyfen provides an added layer of protection for pets and their surroundings. It interrupts the flea life cycle at multiple stages, halting the growth and development of insect eggs and larvae and preventing reinfestation.

    Main Purpose
    To prevent flea eggs from hatching and larvae from growing.

    Active Ingredients % by Weight
    Imidacloprid 8.80%
    Permethrin* 44.00%
    Pyriproxyfen 0.44%
    Other Ingredients 46.76%
    Total 100%

    Useful Information

    How to Apply

    Applying K9 Advantix II to your pet is a fast and easy process. First, remove the K9 Advantix II applicator tube from its packaging and use scissors to peel down the foil. Next, hold the applicator tube in an upright position and pull the cap off the tube. Use the upturned cap to break the protective seal, and you're ready for application.


    For easiest application, your dog should be standing upright. Evenly apply the entire contents of the K9 Advantix II tube to two or three spots from the back of the shoulder to the base of the tail. Part the hair at each spot until the skin is visible, then place the tip of the tube on the skin and gently squeeze out a portion of the solution. Be careful not to apply an excessive amount of the solution in any one spot, otherwise, some of the solutions might run off the side of your dog. Dispose of the container and do not reuse or refill. Do not empty unused product in any indoor or outdoor drain.


    For optimal control and prevention of parasites, use K9 Advantix II every month. K9 Advantix II is available in four- and six-month supplies. Do not use K9 Advantix II on cats or any animals other than dogs.

    Application Instructions

    Evenly apply the entire contents of the tube to four to six spots on the top of the back--from the shoulder to the base of the tail. Apply monthly.

    Length of Effectiveness

    Under normal conditions, the product is effective for one month. However, in cases of a severe flea infestation, retreatment may be necessary earlier than four weeks. Do not retreat more often than once every seven days. After flea control is attained, return to a monthly retreatment schedule.

    Hazards to Humans

    Causes eye irritation. Harmful if swallowed. Do not get in eyes or on clothing. Avoid contact with skin. Wash hands thoroughly with soap and warm water after handling.

    Hazards to Domestic Animals

    *For external use on dogs only.
    *Do NOT use on animals other than dogs.
    *Do NOT use on puppies under seven weeks of age.

    Do not get this product on dog's eyes or mouth. Consult your veterinarian before using this product on debilitated, aged, pregnant, or nursing animals. Individual sensitivities, while rare, may occur after using any pesticide product for pets. If signs persist, or become more severe, consult a veterinarian immediately. If your animal is on medication, consult your veterinarian before using this product.

    Do Not Use on Cats

    Due to their unique physiology and inability to metabolize certain compounds, cats must not use this product. If applied to a cat, or ingested by a cat that actively grooms a recently treated dog, this product may have serious harmful effects. If this occurs, contact your veterinarian immediately.

    Environmental Hazards

    This product is extremely toxic to fish. Do not add directly to water. Do not contaminate water when disposing of product or package.

    First Aid

    Have the product container or label with you when calling a poison control center or doctor, or when going for treatment.

    If in eyes: Hold eye open and rinse slowly and gently with water for 15 to 20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice.

    If swallowed: Call poison control center or doctor immediately for treatment advice. Have person sip a class of water if able to swallow. Do not induce vomiting unless told to do so by the poison control center or doctor. Do not give anything by mouth to an unconscious person.

    If on skin or clothing: Take off contaminated clothing. Rinse skin immediately with plenty of water for 15 to 20 minutes. Call a poison control center or doctor for treatment advice.

    To physician: Treat patient symptomatically.

    Keep out of reach of children.

    Customer Reviews

    100 Reviews
    89% (89)
    9% (9)
    0% (0)
    1% (1)
    1% (1)
    99% Recommend this product (99 of 100 responses)
    By Lablady
    Saluda, MC
    July 30, 2018
    Grew protector for my fogs
    I have used this product for many years,,, I fleas no or ticks....
    ProsEasy to use..works well
    By Abby
    July 25, 2017
    Works great for my dogs!
    This is my preferred flea/tick prevention for my 6 Labradors. Works great!
    By Dan
    July 16, 2017
    Review for 12 MONTH K9 Advantix II BLUE for Extra Large Dogs (over 55 lbs)
    Have used this on my dogs for years. Never had a problem.
    By Jessie M.
    Payson, AZ
    May 12, 2017
    Best flea and tick protection on earth
    I have been using K9 Advantix for at least 15 years. I have had numerous dogs during that time, and lived in the mountains, the valley, and the desert. I have NEVER seen a flea or tick on any of my dogs during any of that time. They go swimming in the creeks in the summer, running thru the tall grass, and still - no fleas or ticks. Vets often tell me there is a newer greater product on the market but I say No Thanks! This one works and I'm sticking with it.
    By JR
    Rural NE OK
    April 26, 2016
    Great Stuff
    I have been using K9 Advantix II for years now. I live in rural Ok and ticks are my dogs worst enemies, we tried many other products over the years and K9 Advantix II really does work the best, plus we live right next to a river and it seems to help with mosquitoes as well. I wouldn't use anything else !!!
    By Sue
    April 1, 2016
    Review for 12 MONTH K9 Advantix II BLUE for Extra Large Dogs (over 55 lbs)
    Best product never had any issues with this product. Have used it for many years
    By ycats
    Atlanta, GA
    March 15, 2016
    Best Ever
    Best Flea and Tick control ever. 2 large dogs in the woods all year and never have flea or tick problem.
    By smk
    September 26, 2015
    Wouldn't use anything else
    I used Advantix products on my Lab/Shepherd mix for almost 14 years. A few months ago, I had to put Sofia down. Two weeks ago, I got a puppy. I will use Advantix on Connery.
    By Pyrparent
    September 7, 2015
    No fleas or ticks
    This year has been bad for ticks and fleas. Lots of rain and tall grass, but my dogs are flea and tick free thanks to K9 Advantix II. The dogs have never had any skin irritation where the product is applied, and no other side effects either. Great product that really works. The X-L size works for all the dogs, ranging from 60 to 120 lbs.
    By Love D.
    July 8, 2015
    Great success
    I've had great success over the years keeping ticks and fleas away using Advantix.
    By Flea B.
    June 18, 2015
    Worst Ever
    We have been using the formula for 55+ for 2 months now. Both dogs continue to have fleas visibly running on them and hopping on us. Unfortunately, we bought 2 boxes of this and are stuck with it. It has been 3 weeks since the last dose and I am going to try dosing again and see if there is some kind of cumulative effect. We have sprayed the carpets and furniture with flea spray and still the fleas are crawling all over us. Proof that if you lie down with dogs, you get up with fleas. But it shouldn't be happening with this product on them. Not a happy shopper at all!
    By gmn
    May 5, 2015
    K9 Advantix II Blue x-lrg for dogs >55lbs
    This product seems to work. Very messy and a lot of liquid, tends to run. Will stain walls if dog leans against them.
    By EMMAZ
    April 29, 2015
    GOOD product
    I have continued to have good results using this product. It doesn't bother the skin or coat of my dogs, and has been very effective against fleas.
    By Shel D.
    Berkeley, CA
    February 14, 2015
    Flea Killer and Protector Against Fleas
    This is the best flea prevention ointment we have every used. We have been using it on our dogs for may years.
    By Leslie
    Bath County, VA
    January 21, 2015
    K-9 Advantix II
    Great product - we live in the country and it keeps the ticks off our puppies - we have 5. I watch for your specials and you have the best price I've found.
    By Jo
    September 10, 2014
    Good price
    We've shopped this price around a bit and this is a good one.
    By Smokey
    California, MD
    August 6, 2014
    Best Purchase Ever
    K9 Advantix II is amazing, never worry about fleas, ticks or mosquitoes. Great price and fast delivery. Very satisfied!
    By MC
    August 3, 2014
    The product works. No flea problems, and most definitely helps keep the mosquitoes away. Generally only have to use once every 2-3 months to keep the dogs from scratching from bites.

    It may be pricier than other products but you do get what you pay for.
    By DD
    Jacksonville, FL
    July 16, 2014
    Great price for a reliable product
    Have used this product regularly on all four of our large breed dogs and never worry about fleas, ticks or mosquitoes. Great price and fast delivery. Very satisfied!
    By daibro
    Evansville, In
    June 1, 2014
    can always count on
    I like the K9 Advantix II as my dogs are in the woods and tall grasses a lot an I don't have to worry as much about the ticks. They still get a few but most are dead when I find them. Also like Entirely pets prices on this product.
    By Bill
    Toronto, Canada
    May 26, 2014
    Good quality excellent prices super fast shipping.
    By gibson
    Geneva Ohio
    May 2, 2014
    Best out there...
    K9 Advantix ll is the ONLY flea and tick med that I will buy.. Unlike other flea and tick med. it DOES REALLY WORK....
    By Ruby T.
    Los Angeles, CA
    April 16, 2014
    Review for 12 MONTH K9 Advantix II BLUE for Extra Large Dogs (over 55 lbs)
    I have three large dogs and this product works well. I have tried other brands but this one works the best for me.
    By JerseyGirlMel
    March 28, 2014
    Best flea & tick product ever!
    This is the most effective flea & tick product ever! I have been using it for years and have never seen a flea or tick on my dogs or in my house!
    By Bill
    Pittsburgh, PA
    March 12, 2014
    Pleased with the PROTECTION
    I began using Advantix II more than a year ago and have found it to be quite effective. I tried other flea and tick medications, but none tried were as effective as Advantix II. I recommend it highly.
    By That B.
    Blue Ridge GA
    January 30, 2014
    Great Price !!!
    product has always worked to keep my dog Bug Free ! ! !

    Price Point was perfect !!
    By Marty
    October 30, 2013
    Used for years!
    We have used this forever and very, very seldom see or have fleas or ticks. It is used all year long!
    By DHS
    North East Louisiana
    September 27, 2013
    Works best at the best price
    We are an animal rescue in Northeast Louisiana. Fleas are a year round problem. We are constantly making price comparisons as we are funded only by donations. K9 Advantix II at Entirely Pets is the most effective OTC product we've found, for the best price. Free shipping is a plus too!!
    By Tongster
    August 1, 2013
    Great price
    I have two labs and Entirely Pets has the best price for this product. This product also kills ticks, which I have in my area. Great product and price and it comes so quickly in the mail.
    By Callmond
    Macon, GA
    July 29, 2013
    Great protection for my dogs!
    I switched to K9 Advantix a few years ago after Frontline Plus stopped working as well and I was impressed with how much protection this gave. My dogs are primarily outside and I've always had issues with flies and mosquitoes bothering them even with Frontline but that's no longer an issue with Advantix. My dogs are happy and so am I!

    Questions and Answers

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