1. Home > 
  2. Dog Supplies > 
  3. Flea & Tick Supplies > 
  4. Topicals > 
  5. FRONTLINE® Plus for Dogs > 
  6. Frontline Plus for Dogs 89-132 lbs - RED, 6 MONTH

Frontline Plus for Dogs 89-132 lbs - RED, 6 MONTH Video
Frontline Plus for Dogs 89-132 lbs - RED, 6 MONTH Video

Frontline Plus for Dogs 89-132 lbs - RED, 6 MONTH

Item: FPLUS6RD132
1. Select dosage:
2. Select weight:


Temporary Price Reduction! Frontline PLUS Red for Dogs 89-132 lbs

Recommended by veterinarians, Frontline PLUS Red for Dogs 89-132 pounds is a powerful and easy-to-use formula designed to quickly and effectively kill fleas, ticks, and chewing lice. FRONTLINE Plus is specially formulated for dogs weighing 89-132 pounds. Available without a prescription, FRONTLINE Plus only needs to be applied once a month for thorough pest control.

life cycle of the commom flea
Flea life cycle.
View larger.
life cycle of ticks
Tick life cycle.
View larger.

Quickly Kills Fleas, Ticks, and Chewing Lice

This powerful formula kills up to 100 percent of existing fleas in the first 12 hours after application, and it continues to kill new fleas for at least one month afterward. FRONTLINE Plus prevents the development of new fleas by destroying flea eggs and larvae and by destroying adult fleas before they have a chance to lay eggs. FRONTLINE kills chewing lice and all four major ticks, including ticks that may carry Lyme disease, keeping both your pet and your family protected.

Waterproof Formula

Thanks to its waterproof formula, FRONTLINE Plus won't rinse off when you give your dog a bath or when your dog goes for a swim. The active ingredient in FRONTLINE, fipronil, is stored in the natural oils in your dog's coat, so your pet is sure to stay protected no matter how many puddles he or she tramps through.

EPA Registered Logo

This FRONTLINE Plus product is EPA approved and registered, so it's guaranteed to be the exact same product sold by your Veterinarian. Click here for more information on EPA-approved pet products.

Package Contents

Box includes three 4.02-milliliter tubes of FRONTLINE Plus for Dogs.

Frontline PLUS Red
for Dogs 89-132 lbs
  • Kills fleas, flea eggs, ticks, and
    chewing lice
  • Fast-acting formula
  • Includes 6 one-month
  • Waterproof formula
  • Easy-to-use applicator
  • For dogs weighing 89-132 pounds
  • Per Dose: $12.50
More Info
Got Fleas?

A product guide to flea
and tick products.

Flea Facts You Should Know

Interesting flea facts to help your
pets be pest free.

Fleas: Understanding the Enemy

All about fleas and prevention.


Helpful information on ticks and your

FAQs about Fleas and Ticks
Frontline Plus for Dogs Lifestyle shot
FRONTLINE Plus for Dogs is Available In:
(0 - 22 pounds)
(23 - 44 pounds)
(45 - 88 pounds)
(89 - 132 pounds)
3 month
6 month
12 month
3 month
6 month
12 month
3 month
6 month
12 month
3 month
6 month
12 month



Fipronil is a manufactured insecticide that works on a cellular level on adult fleas and ticks. It seeps into an insect's cells and blocks chlorine molecules from passing through. This stops the nervous system from working and paralyzes the insect.

Fipronil kills adult fleas and ticks on contact or when consumed, and it can be spread from one insect to another.


Because fipronil is so strong, it only needs to be applied once a month to continuously kill fleas and ticks. Once it is applied with an oily liquid to keep it on the skin of your dog, it slowly seeps into the hair follicles and oil glands where the fleas and ticks live.

Main Purpose

To kill adult fleas and ticks.


Methoprene is an insect growth regulator, which means it works by affecting the eggs and larvae of fleas. It interrupts normal levels of growth hormone, preventing a juvenile flea from growing and molting, leading to death.


Specifically designed to target developing larvae and eggs, methoprene prevents a flea population from increasing.

Main Purpose

To break the flea life cycle and stop further infestation.

Active Ingredients % by Weight
Fipronil 9.8%
(S)-Methoprene 8.8%
Inert Ingredients 81.4%
Total 100%

Some animals are sensitive or allergic to the ingredients in FRONTLINE, so be sure to watch for any signs of allergic reaction. If your pet shows signs of itching, restlessness, nausea, lethargy, or breathing difficulty, seek veterinary attention immediately.

Net Contents

Six tubes, each 0.136 fluid ounces (4.02 milliliters)

Useful Information

How FRONTLINE Plus Works

Use FRONTLINE Plus for fast-acting, long-lasting flea and tick control. When you apply FRONTLINE, fipronil, the active ingredient, is stored in the oil glands under your pet's skin. It's then distributed continuously to the skin and hair of your pet through the hair follicles. This way, FRONTLINE provides waterproof, month-long protection against future pests while breaking down the flea and tick life cycles.

Simple Three-Step Application

Applying FRONTLINE Plus to your pet is an easy three-step process. First, remove the Frontline Plus applicator from the child-resistant package and cut or lift off the plastic tab to expose the foil and then peel the foil down. Next, hold the applicator upright and away from your face and body and snap off the tip. Finally, place the Frontline Plus applicator tip on the skin between your pet's shoulder blades and squeeze the applicator to apply the entire contents in a single spot onto your pet's skin.

To prevent harm to you and your pet, read the entire label and enclosed directions before each use. Follow all directions and precautionary statements carefully.


To prevent harm to you and your pet, read the entire label and enclosed directions before each use. Follow all directions and precautionary statements carefully. Always point the applicator away from your face, especially your eyes, and wash your hands thoroughly after application. USE ON DOGS ONLY. Do not use on rabbits or other animals.

Weight Dosage
Up to 22 pounds Apply contents of one applicator (0.67 milliliter) once per month
23 - 44 pounds Apply contents of one applicator (1.34 milliliters) once per month
45 - 88 pounds Apply contents of one applicator (2.68 milliliters) once per month
89 - 132 pounds Apply contents of one applicator (4.02 milliliters) once per month
All weights Apply contents of one applicator (0.5 milliliter) once per month

Customer Reviews

34 Reviews
82% (28)
6% (2)
3% (1)
0% (0)
9% (3)
85% Recommend this product (29 of 34 responses)
By Linda G.
May 28, 2018
So easy!
Ordering Frontline on line saved me one more trip to the store, and money! And when you have a dog who wakes you up, you want to be sure he's not bringing fleas and ticks with him!
ProsThey're so entertaining!
Conslots of work
By Susan L.
Lake Forest, CA
June 21, 2017
Worry No More!
My three dogs, Sage, Minnie, and Chance all receive flea & tic protection via this product. We walk in wooded areas regularly. I'm glad they can leave the worrying about deadly diseases to me and Frontline Plus!
By Cindy
Eustis, Florida
May 16, 2017
Frontline Plus
Great product easy application. Works quickly
By kcc
June 24, 2016
It works!
It seems to work. No fleas, ticks, etc.!
By Paula
Southern California
August 22, 2015
Frontline didn't work
I have used Frontline in the past years but this year in SoCal it didn't work at all. I ended up getting Advantix II which worked like a charm.
By Akitagirl3
Gresham, OR
August 12, 2015
Excellent Product
The only product I trust for my Akita dogs!
By Connie
September 12, 2014
Frontline Plus does not work anymore
The fleas laugh at this stuff. Ended up going to the vet and getting comfortis.
By bikerdave
New Castle DE
July 21, 2014
This product is easy to apply and seems to work well on my 106 lb. German Shepherd
By Charley's M.
St Petersburg, Florida
March 7, 2014
Review for Frontline Plus for Dogs 89-132 lbs - RED, 6 MONTH
This is a safe and very effective product. I've been using it for years with much success. Entirely Pets always has the best price on this product.
By Patricia
January 11, 2014
Review for Frontline Plus for Dogs 89-132 lbs - RED, 6 MONTH
Still the best flea medicine I have used on my pets. The cat version was not as effective. Would love a bedding wash version...
By zzed28
December 22, 2013
not perfect
This product works for the most part, but tends to only last two or three weeks before re appearance of visible fleas.
By Lamblady
August 22, 2013
flea product
This product did not take care of the fleas, I want to know why. Alot of money for a product that does not work:(
By Higgins
July 30, 2013
Super Fast Delivery
Quality product at super price and super fast delivery!
By Amfbob
July 29, 2013
Frontline Plus- Large Dogs
Used this for several years with great success.
By ng
White Pine, TN
June 12, 2013
Dog and Horses
I recently ordered this product and I always get such excellent responses to my orders. They are taken care of in a couple of days and I receive them with no problems. I have a dog and I also have horses, with which I order cosequin, a joint product for the horses, this stuff is wonderful, would not be without it. Entirely Pets always emails me with specials on Dog products and horse products. I highly recommend these products and the savings are great.......ng
By skittles
June 10, 2013
best on fleas
Have been using this on my dog for years now. Easy and not messy to use. Best product for my big dog.
By larry
April 23, 2013
Great price
Just in time. A very good product @ a very good price.
By Lynn O.
The Villages FL
April 23, 2013
Started using this product close to a year ago and have had absolutely no problems with fleas or ticks on my yellow lab. As you can see, Rusty is very active!
April 15, 2013
Flea free
This size of Frontline Plus allows me to treat both our dogs with the one application. I have a 55 lb. and a 16 lb. It is a savings to do it this way. I use it along with a Preventic Tick Collar for the added tick prevention. Entirely Pets is a trusted business that I have ordered from many times.
By Michele
January 24, 2013
Great Products
Pleasure to do business with - fast and easy.....Same products at reduced orices.
By horse1
December 8, 2012
Purchase all the time
I have never had problems with EntirelyPets with any of my orders. I have checked other places and they seem to have the best deals.
By cc
November 25, 2012
Frontline Plus
This works great for my dogs. No fleas if i use it consistently. However, I tend to skip months. When I do notice a flea on anyone of my dogs, I use Frontline Plus immediately and the next day, no more fleas for a couple of months. I use it more often during summer time. This also helps with ticks!
By DonnaD
Pittsburgh, PA
November 6, 2012
Great transaction, would buy again
Got a great deal on Frontline. It's the only flea and tick suggested by vets and even considered by me. Works great. Fast delivery too!
By jpneenr1
Wilkes-Barre, PA
August 9, 2012
frontline plus for dogs
Frontline plus for dogs.....very good product....never have a problem and easy to apply.
Entirelypets.com provides a great service.
By Mt M.
July 26, 2012
Protects all 3 of my pets, 2 Bouvier & a Mini. Schnauzer.
By Rhonda
Visalia, CA
May 30, 2012
Excellent product, great price and customer service.
By Linn
May 30, 2012
Solves flea problems.
Have used Frontline for a long time, no flea problems, some tics make it into house but don't latch on to dogs.
By dave
jerusalem ohio
April 17, 2012
good value and fast delivery
good value and fast delivery best prices i have seen around
By big d.
Washington state
April 9, 2012
great products, great prices
Frontline works really well and very quickly. It is easy to administer and causes no trauma to my dog.
By The l.
March 15, 2012
Great product
Have used this product for years and have never had a flea problem since. I live in the south and fleas are an issue year round - this has really worked for me and my three dogs.

Questions and Answers

There are no questions or answers for this item.

Frontline Plus for Dogs 45-88 lbs - PURPLE, 12 MONTHFrontline Plus for Dogs 45-88 lbs - PURPLE, 12 MONTHReg price: $191.99
Sale price: $146.99
Frontline Plus for Dogs 89-132 lbs - RED, 3 MONTHFrontline Plus for Dogs 89-132 lbs - RED, 3 MONTHReg price: $43.99
Sale price: $33.79
Frontline Plus for Dogs 89-132 lbs - RED, 12 MONTHFrontline Plus for Dogs 89-132 lbs - RED, 12 MONTHReg price: $172.99
Sale price: $132.99
Frontline Plus for Dogs 0-22 lbs- ORANGE, 3 MONTHFrontline Plus for Dogs 0-22 lbs- ORANGE, 3 MONTHReg price: $46.99
Sale price: $35.99
CALL IN YOUR ORDER 800.889.8967

Stay in touch. Friends fur-ever!

Terms and Conditions

You have to agree on terms in order to proceed to the subscription.